Patents by Inventor Nuria Aguilar Izquierdo

Nuria Aguilar Izquierdo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted spiro[cycloalkyl-1,3?-indo]-2?(1?H)-one derivatives and their use as P38 mitogen-activated kinase inhibitors
    Patent number: 8772288
    Abstract: The present disclosure is directed to new inhibitors of the p38 mitogen-activated protein kinase having the general formula (I), processes for preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: April 3, 2009
    Date of Patent: July 8, 2014
    Assignee: Almirall, S.A.
    Inventors: Paul Robert Eastwood, Jacob Gonzalez Rodriguez, Bernet Vidal Juan, Nuria Aguilar Izquierdo
  • 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE
    Publication number: 20110311485
    Abstract: The present disclosure relates to 1, 2, 4 oxadiazole derivatives of formula (I) as well as pharmaceutical compositions comprising them, and their use in therapy as agonists of the S1P1 receptors.
    Type: Application
    Filed: December 15, 2009
    Publication date: December 22, 2011
    Applicant: ALMIRALL S.A.
    Inventors: Victor Giulio Matassa, Nuria Aguilar Izquierdo, Marta Mir Cepeda, Marta Carrascal Riera, Silvia Fonquerna Pou, Aranzazu Cardus Figueras, Julio Cesar Castro Palomino Laria, Montserrat Erra Sola
  • OXADIAZOLE DERIVATIVES AS S1P1 RECEPTOR ANTAGONISTS
    Publication number: 20110274657
    Abstract: The present disclosure relates to oxadiazole derivatives of formula (I) as well as pharmaceutical compositions comprising them, and their use in therapy as agonists of the S1P1 receptor.
    Type: Application
    Filed: January 14, 2010
    Publication date: November 10, 2011
    Inventors: Nuria Aguilar Izquierdo, Marta Carrascal Riera, Julio Cesar Castro Palomino Laria, Montserrat Erra Sola
  • NEW 2-AMIDOTHIADIAZOLE DERIVATIVES
    Publication number: 20110200557
    Abstract: The present disclosure relates to 2-amidothiadiazole derivatives of formula (I) as well as pharmaceutical compositions comprising them, and their use in therapy as agonists of the S1P1 receptors.
    Type: Application
    Filed: October 13, 2009
    Publication date: August 18, 2011
    Inventors: Pedro Manuel Grima Poveda, Nuria Aguilar Izquierdo, Marta Mir Cepeda, Manuel Lopez Martinez
  • SUBSTITUTED SPIRO[CYCLOALKYL-1,3'-INDOL]-2'(1'H)-ONE DERIVATIVES AND THEIR USE AS P38 MITOGEN-ACTIVATED KINASE INHIBITORS
    Publication number: 20110053936
    Abstract: The present disclosure is directed to new inhibitors of the p38 mitogen-activated protein kinase having the general formula (I), processes for preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: April 3, 2009
    Publication date: March 3, 2011
    Inventors: Paul Robert Eastwood, Jacob Gonzalez Rodriguez, Bernat Vidal Juan, Nuria Aguilar Izquierdo
  • NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES
    Publication number: 20100204241
    Abstract: Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4: wherein R1, R2 and R4 are organic radicals, R3 is a cyclic group, and R5 is an ester or an aryl or heteroaryl group.
    Type: Application
    Filed: October 8, 2008
    Publication date: August 12, 2010
    Inventors: Vittorio Dal Piaz, Nuria Aguilar Izquierdo, Maria Antonia Buil Albero, Marta Carrascal Riera, Jordi Gracia Ferrer, Maria Paola Giovannoni, Claudia Vergelli
  • NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES
    Publication number: 20090111819
    Abstract: Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4: wherein R1, R2 and R4 are organic radicals, R3 is a cyclic group, and R5 is an ester or an aryl or heteroaryl group.
    Type: Application
    Filed: October 8, 2008
    Publication date: April 30, 2009
    Inventors: Vittorio Dal Piaz, Nuria Aguilar Izquierdo, Maria Antonia Buil Albero, Marta Carrascal Riera, Jordi Gracia Ferrer, Maria Paola Giovannoni, Claudia Vergelli
  • Pyridazin-3(2H)-one derivatives and their use as PDE4 inhibitors
    Patent number: 7511038
    Abstract: New pyridazin-e-(2H)-one derivatives having the chemical structure of general formula (I) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of phosphodiesterase 4.
    Type: Grant
    Filed: November 8, 2004
    Date of Patent: March 31, 2009
    Assignee: Laboratorios Almirall S.A.
    Inventors: Vittorio Dal Piaz, Nuria Aguilar Izquierdo, Maria Antonia Buil Albero, Yolanda Garrido Rubio, Maria Paola Giovannoni, Jordi Gracia Ferrer, Wenceslao Lumeras Amador, Claudia Vergelli
  • Pyridazin-3(2H)-one derivatives
    Patent number: 7491722
    Abstract: Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4. R1, R2 and R4 are organic radicals, R3 is a cyclic group, and R5 is an ester or an aryl or heteroaryl group.
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: February 17, 2009
    Assignee: Laboratorios Almirall S.A.
    Inventors: Vittorio Dal Piaz, Nuria Aguilar Izquierdo, Maria Antonia Buil Albero, Marta Carrascal Riera, Jordi Gracia Ferrer, Maria Paola Giovannoni, Claudia Vergelli
  • Pyridazin-3(2H)-One Derivatives And Their Use As Pde4 Inhibitors
    Publication number: 20090029996
    Abstract: The invention relates to new therapeutically useful pyridazin-3(2H)-one derivatives, to processes for their preparation and to pharmaceutical compositions containing them. These compounds are potent and selective inhibitors of phosphodiesterase 4 (PDE4) and are thus useful in the treatment, prevention and suppression of related pathological conditions, diseases and disorders, in particular asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, topic dermatitis, psoriasis or irritable bowel disease.
    Type: Application
    Filed: June 21, 2005
    Publication date: January 29, 2009
    Inventors: Nuria Aguilar Izquierdo, Marta Carrascal Riera, Vittorio Dal Piaz, Jordi Gracia Ferrer, Wenceslao Lumeras Amador, Maria Del Carmen Masdeu Margalef, Graham Warrellow
  • Pyridazin-3(2)-one derivatives as PDE4 inhibitors
    Patent number: 7459453
    Abstract: New pyridazin-3(2H)-one derivatives having the chemical structure of general formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of phosphodiesterase 4.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: December 2, 2008
    Assignee: Laboratorios Almirall, S.A.
    Inventors: Vittorio Dal Piaz, Maria Paola Giovannoni, Claudia Vergelli, Nuria Aguilar Izquierdo
  • PYRIDAZIN-3 (2H) -ONE DERIVATIVES AS PDE4 INHIBITORS
    Publication number: 20080269235
    Abstract: New pyridazin-3(2H)-one derivatives having the chemical structure of general formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of phosphodiesterase 4.
    Type: Application
    Filed: June 18, 2008
    Publication date: October 30, 2008
    Inventors: Vittorio Dal Piaz, Maria Paola Giovannoni, Claudia Vergelli, Nuria Aguilar Izquierdo
  • Pyridazin-3(2)-one derivatives and their use as pde4 inhibitors
    Publication number: 20070197536
    Abstract: New pyridazin-e-(2H)-one derivatives having the chemical structure of general formula (I) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of phosphodiesterase 4.
    Type: Application
    Filed: November 8, 2004
    Publication date: August 23, 2007
    Inventors: Vittorio Dal Piaz, Nuria Aguilar Izquierdo, Maria Buil Albero, Yolanda Garrido Rubio, Maria Giovannoni, Jordi Gracia Ferrer, Wenceslao Lumeras Amador, Claudia Vergelli
  • New pyridazin-3(2h)-one derivatives
    Publication number: 20060173008
    Abstract: Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4. R1, R2 and R4 are organic radicals, R3 is a cyclic group, and R5 is an ester or an aryl or heteroaryl group.
    Type: Application
    Filed: December 22, 2003
    Publication date: August 3, 2006
    Inventors: Vittorio Dal Piaz, Nuria Aguilar Izquierdo, Maria Buil Albero, Marta Carrascal Riera, Jordi Gracia Ferrer, Maria Giovannoni, Claudia Vergelli
  • Pyridazin-3(2h)-one derivatives as pde4 inhibitors
    Publication number: 20060052379
    Abstract: New pyridazin-3(2H)-one derivatives having the chemical structure of general formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of phosphodiesterase 4.
    Type: Application
    Filed: May 14, 2003
    Publication date: March 9, 2006
    Inventors: Vittorio Dal Piaz, Maria Giovannoni, Claudia Vergelli, Nuria Aguilar Izquierdo