Abstract: A thermal management system is provided. The thermal management system includes a housing extending between a leading end and a trailing end. The housing includes a cooling structure defining at least one inlet, at least one outlet, and a duct coupled in flow communication between the at least one inlet and the at least one outlet. The cooling structure is configured to generate a fluid flow from the at least one inlet to the at least one outlet through the duct in response to the housing moving through a fluid. The thermal management system further includes an electronics assembly disposed in contact with the cooling structure. The cooling structure is configured to transfer heat generated by the electronics assembly to the fluid moving through the duct to cool the electronics assembly.

Abstract: Provided herein are methods for determining the serotype of a virus particle and/or or determining the heterogeneity of a virus particle (e.g., an AAV particle). In other embodiments, the invention provides methods to determine the heterogeneity of AAV particles. In some aspects, the invention provides viral particles (e.g., rAAV particles) with improved stability and/or improved transduction efficiency by increasing the acetylation and/or deamidation of capsid proteins.

Abstract: A robotic surgical tool that includes a plate inside of a drive housing. The drive housing is divided into an upper portion and lower portion by the plate. Extending from the drive housing is an elongate shaft. The robotic surgical tool also includes an injection port that passes a cleaning fluid into the drive housing. Inside the drive housing there is a diverter adjacent to the injection port. The diverter has a ramp which can direct fluid from the injection port to the upper portion of the drive housing.

Abstract: An improved tungsten carbide powder comprises (W,Cr) C solid solution phase for oxidation resistance at high temperatures. The improved tungsten carbide powders may be formed by carburizing a mixture of tungsten powder, carbon powder, and Cr2O3 powder. The tungsten carbide powder herein may be used to form ready-to-press (RTP) or grade powders. These RTP may be used to form articles, including articles that require excellent oxidation resistance at high temperature. One such component is a seal ring for a liquid battery.

Abstract: Apparatuses including spark gap structures for electrical overstress (EOS) monitoring or protection, and associated methods, are disclosed. In an aspect, a vertical spark gap device includes a substrate having a horizontal main surface and a plurality of pairs of conductive layers over the horizontal main surface. Different ones of the pairs are separated by different vertical distances such that each pair serves as an arcing electrode pair and different ones of the arcing electrode pairs are configured to arc discharge at different voltages.

Abstract: A system and method for providing zone-specific media to a user. As a non-limiting example, various aspects of this disclosure provide a system and method that flexibly selects and provides media content (e.g., audio content), where such content is selected based, at least in part, on a user location (e.g., location within a premises).

Abstract: Disclosed are techniques and a device operable to determine a total amount of insulin delivered to the user over a predetermined time period. The total amount of insulin includes a total basal dosage delivered in basal dosages and a total bolus dosage delivered in bolus dosages over the predetermined time period. A proportion of the total amount of insulin delivered to the user provided via the total basal dosage amount over the predetermined time period is calculated. In response determining the proportion of the total amount of insulin attributed to the total basal dosage amount of insulin exceeds a threshold, an average basal dosage to be delivered within a subsequent time period that is approximately equal to the threshold may be determined. An instruction may be generated and output to deliver a modified basal dosage that substantially maintains the average basal dosage over the subsequent time period.

Abstract: Disclosed herein, among other things, are systems and methods for cancelling interference from a telecoil signal for ear-wearable devices. A method includes receiving a signal from a telecoil of a hearing device, and using a trigger signal to initiate recordings of segments of the telecoil signal. An interference component is isolated from the telecoil signal using the recorded segments. The interference component is inverted and added to the telecoil signal to cancel the interference component from the telecoil signal, and audio from the telecoil signal is provided to a wearer of the hearing device.

Abstract: Aspects of the disclosure include using piezoelectric devices to break laminated glass assemblies on demand (e.g., a windshield of a vehicle). An exemplary vehicle includes a laminated glass panel having an outer glass layer, an inner glass layer, and a bonding layer between the outer glass layer and the inner glass layer. The vehicle further includes a piezoelectric device including an actuator and a displaceable element coupled to the actuator. The actuator is made of a piezoelectric material that, responsive to receiving an activation voltage, induces a mechanical displacement in the displaceable element against at least one of the outer glass layer and the inner glass layer. The vehicle includes a controller electrically coupled to the actuator. The controller is configured to deliver the activation voltage to the actuator.

Abstract: Some embodiments described in this disclosure are directed to electronic devices that present indications of changes to a shared document and/or to the users in a messaging conversation while displaying the messaging conversation. Some embodiments described in this disclosure are directed to electronic devices that present options to update the users with access to shared documents and/or messaging conversations. Some embodiments described in this disclosure are directed to electronic devices that participate in communication sessions associated with a shared document.

Abstract: The present invention relates to antibodies directed against HLA-G and formulations comprising the same. The invention further relates to the use of the HLA-G antibodies and formulations in therapy, notably in the treatment of solid tumors.

Abstract: The disclosed system provides a neuro-physiological assessment and rehabilitation system. The system selects, based on an injury type, one or more target regions of the patient's brain for assessment of a neurological metric associated with a neurological network of the patient's brain and a first predetermined visual stimulation is provided to the patient while first neurological data pertaining to the athletic performance of the patient reacting to the visual stimulation is received, including measurements pertaining to the neurological metric. The obtained first neurological data is compared to the baseline data threshold and a second visual stimulation configured to prompt the neurological metric toward the baseline data threshold is selected. Second neurological data pertaining to the athletic performance of the patient reacting to the second visual stimulation is received and a state of the neurological metric indicating whether the neurological metric adjusted toward the baseline threshold is provided.

Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.

Abstract: The present invention relates to compositions comprising one or more probiotic bacterial strains and one or more lipid modifing active ingredients. The compositions can be used in the management of cholesterol and/or hypertension.

Abstract: An example methodology includes, by a computing device, determining a recurring time period during which performance data breaches a performance data threshold and applying a data exclusion window on the recurring time period, wherein performance data within the data exclusion window are excluded from system performance calculations. The method also includes, by the computing device, retrieving historical performance data associated with the data exclusion window and determining a percentage of the historical performance data that breach the performance data threshold. The method further includes, responsive to a determination that the percentage of the historical performance data that breach the performance data threshold is within an acceptable breach threshold, removing, by the computing device, the data exclusion window on the recurring time period.

Abstract: A shaped abrasive particle including a body comprising a first major surface, a second major surface, and a side surface extending between the first major surface and the second major surface, the body comprising a sharpness-shape-strength factor (3SF) within a range between about 0.7 and about 1.7 and a Shape Index within a range between at least about 0.01 and not greater than about 0.49.

Abstract: A policy level controller coordinates a scheduling and policy engine using a data change metric to dynamically schedule or re-define policies in response to data change rates in data assets in a current backup session. A supervised learning process trains a model using historical data of backup operations of the system to establish past data change metrics for corresponding backups processing the saveset, and modifies policies dictating the backup schedule by determining a data change rate of received data, as expressed as a number of bytes changed per unit of time. In response to input from backup targets regarding present usage, it then modifies the backup schedule to minimize the impact on backup targets that may be at or close to overload conditions.

Abstract: A surgical tool includes a drive housing, an indicator assembly arranged within the drive housing and actuatable to provide visual indication that the surgical tool has exhausted its useful life. The indicator assembly includes a drive input rotatably coupled to the bottom of the drive housing. The drive input further including a riser and a rim where the riser contains a passage therethrough. The indicator assembly further includes an indicator shaft extending through the passage along a longitudinal axis coaxially aligned with the drive input. The drive input is rotated to actuate the indicator assembly between a non-activated state, where the indicator shaft is recessed into the drive housing, and an activated state, where the indicator shaft extends out of the drive housing to provide the visual indication.

Abstract: An electronic device with a touch-sensitive display displays, on a touch-sensitive display, a first view of a first application. While displaying the first view, the electronic device detects a swipe input from an edge of the touch-sensitive display. In response to detecting at least a first portion of the swipe input from the edge of the touch-sensitive display, the electronic device concurrently displays, on the touch-sensitive display, at least a first application view corresponding to a first application, a second application view corresponding to a second application, and a representation of a home screen user interface that includes representations of a plurality of application launch icons.

Abstract: A method and apparatus for processing documents is provided. The documents may be conveyed to a feeder for feeding documents to a scanner. The scanner scans each document to obtain image data and then discharges the document to one or more output or sort locations. The system may include a skew reduction assembly for reducing skew in the documents as the documents are fed to the scanner. The system may also include elements for improving image quality and reducing document damage while the document is scanned. The system may further include features for improving the stacking of the discharged documents.