Patents by Inventor O. M. Zack Howard

O. M. Zack Howard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cosalane compounds and methods for their use
    Patent number: 7122533
    Abstract: The present invention relates to methods, compounds and compositions for inhibiting effective binding of a chemokine to its cellular receptor. In one form of the invention, a method includes contacting a cellular population with an effective amount of cosalane or an analog thereof. The invention further relates to methods, compounds and compositions for treating inflammatory diseases. In one form, a method includes administering to a patient a therapeutically effective amount of cosalane or an analog thereof.
    Type: Grant
    Filed: May 13, 2003
    Date of Patent: October 17, 2006
    Assignees: The United States of America as represented by the Department of Health and Human Services, Purdue Research Foundation
    Inventors: Mark S. Cushman, O. M. Zack Howard
  • Cosalane compounds and methods for their use
    Publication number: 20030212045
    Abstract: The present invention relates to methods, compounds and compositions for inhibiting effective binding of a chemokine to its cellular receptor. In one form of the invention, a method includes contacting a cellular population with an effective amount of cosalane or an analog thereof. The invention further relates to methods, compounds and compositions for treating inflammatory diseases. In one form, a method includes administering to a patient a therapeutically effective amount of cosalane or an analog thereof.
    Type: Application
    Filed: May 13, 2003
    Publication date: November 13, 2003
    Inventors: Mark S. Cushman, O. M. Zack Howard
  • Ureido derivatives of poly-4-amino-2-carboxy-1-methyl pyrrole compounds for inhibition of inflammation
    Patent number: 6562859
    Abstract: A method of using a ureido derivative of a poly-4-amino-2-carboxy-1-methyl pyrrole or a pharmaceutically acceptable salt thereof to inhibit inflammation, particularly non-TNF-&agr; dependent inflammation, in a mammal.
    Type: Grant
    Filed: August 4, 2000
    Date of Patent: May 13, 2003
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: O. M. Zack Howard, Joost J. Oppenheim, William J. Murphy, Edward A. Sausville
  • Cosalane compounds and methods for their use
    Patent number: 6562805
    Abstract: The present invention relates to methods, compounds and compositions for inhibiting effective binding of a chemokine to its cellular receptor. In one form of the invention, a method includes contacting a cellular population with an effective amount of cosalane or an analog thereof. The invention further relates to methods, compounds and compositions for treating inflammatory diseases. In one form, a method includes administering to a patient a therapeutically effective amount of cosalane or an analog thereof.
    Type: Grant
    Filed: January 29, 2001
    Date of Patent: May 13, 2003
    Assignees: Purdue Research Foundation, The United States of America as represented by the Department of Health and Human Services
    Inventors: Mark S. Cushman, O. M. Zack Howard