Patents by Inventor O. Manuel Uy
O. Manuel Uy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120164027Abstract: A device for measuring and detecting the organophosphorus compounds, such as a pesticides or a nerve agents is provided. The devices function by selectively binding an organophosphorous compound to a luminescent functionality-imprinted copolymer. The copolymers possess a securely bound luminescent lanthanide ion, such as Eu3+, in a coordination complex that has been templated for the chemical functionality.Type: ApplicationFiled: August 26, 2008Publication date: June 28, 2012Inventors: George M. Murray, O. Manuel Uy, Amanda L. Jenkins
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Patent number: 7416703Abstract: A device for measuring and detecting the organophosphonis compounds, such as a pesticides or a nerve agents is provided. The devices function by selectively binding an organophosphorous compound to a luminescent functionality-imprinted copolymer. The copolymers possess a securely bound luminescent lanthamide ion, such as Eu3+, in a coordination complex that has been templated for the chemical functionality.Type: GrantFiled: August 16, 2004Date of Patent: August 26, 2008Assignee: The Johns Hopkins UniversityInventors: George M. Murray, O. Manuel Uy, Amanda L. Jenkins
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Patent number: 6967103Abstract: An explosive detector that utilizes an array of molecularly imprinted polymer (MIP) coated, bifurcated fiber optic cables to form an image of a target molecule source. Individual sensor fiber assemblies, each with a calibrated airflow, are used to expose the fibers to the target molecule. The detector energizes a dedicated excitation light source for each fiber, while simultaneously reading and processing the intensity of the resulting fluorescence that is indicative of the concentration of the target molecule. Processing electronics precisely controls the excitation current, and measures the detected signal from each narrow band pass filter and photodiode. A computer with display processes the data to form an image of the target molecule source that can be used to identify the source even when low level contamination of the same molecule is present. The detector can be used to detect multiple and/or non-explosive targets by varying the MIP coating.Type: GrantFiled: May 3, 2001Date of Patent: November 22, 2005Assignee: The Johns Hopkins UniversityInventors: Paul D. Schwartz, George M. Murray, O. Manuel Uy, Binh Q. Le, David D. Scott, Ark L. Lew, Sharon X. Ling, Joseph J. Suter
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Patent number: 6924147Abstract: A polymeric food spoilage sensor comprises a polymer containing a polyazamacrocyclic transition metal complex. The complex selectively binds biogenic amines, such as cadaverine, putrescine and histamine, which are released by food spoilage microorganisms. The polymer undergoes a detectable color change upon exposure to biogenic amine, thus indicating that food spoilage has probably occurred. In one embodiment, the polymer is molecularly imprinted with the biogenic amine to impart selective binding affinity. The polymer is easily incorporated in common food containers and can be employed in fiber optic detection devices.Type: GrantFiled: July 15, 2003Date of Patent: August 2, 2005Assignee: The Johns Hopkins UniversityInventors: Craig A. Kelly, George M. Murray, O. Manuel Uy
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Patent number: 6852891Abstract: A method of inhibiting or preventing the use of anhydrous ammonia as a solvent in a dissolving metal reduction process comprises adding to anhydrous ammonia a chemical reagent which is capable of scavenging solvated electrons generated when alkali or alkaline earth metal is dissolved in the anhydrous ammonia, the chemical reagent being added to the anhydrous ammonia such that when alkali metal is dissolved in the anhydrous ammonia containing the chemical reagent and thereafter ephedrine, pseudoephedrine or combination thereof is introduced to the anhydrous ammonia to produce a reaction product, the methamphetamine yield in the reaction product is below 50%, preferably below 10%, and more preferably below 1%. Preferred chemical reagents include Fe(III)citrate, ferrocene, 2-chloro-6-(trichloromethyl)pyridine and 1,1,1,2-tetrafluoroethane.Type: GrantFiled: June 21, 2001Date of Patent: February 8, 2005Assignee: The Johns Hopkins UniversityInventors: George M. Murray, Craig A. Kelly, O. Manuel Uy, Lawrence W. Hunter, David S. Lawrence
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Patent number: 6706977Abstract: A controller for a quartz crystal microbalance (QCM) sensor system and method for detecting mass deposition on a QCM sensor. The controller controls a QCM using temperature-, voltage- and current-regulating circuits, a microcontroller, an oscillator, heating and cooling devices and circuits, high voltage grids, digital-to-analog and analog-to-digital converters, data telemetry and uplink circuits, and a remote user. The remote user may be a person, computer, network or data logger. The remote user allows the controller to be reconfigurable during operation. The controller samples and reports data faster and is more reliable over extended periods of operation. Further, the controller is assembled using innovative techniques making it smaller and thus more transportable, easier to incorporate into existing facilities and less expensive to construct and operate. The apparatus may also be assembled in a modular fashion that allows for customization.Type: GrantFiled: August 26, 2002Date of Patent: March 16, 2004Assignee: The Johns Hopkins UniversityInventors: Russell P. Cain, Bliss G. Carkhuff, O. Manuel Uy
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Publication number: 20040049079Abstract: A method of inhibiting or preventing the use of anhydrous ammonia as a solvent in a dissolving metal reduction process comprises adding to anhydrous ammonia a chemical reagent which is capable of scavenging solvated electrons generated when alkali or alkaline earth metal is dissolved in the anhydrous ammonia, the chemical reagent being added to the anhydrous ammonia such that when alkali metal is dissolved in the anhydrous ammonia containing the chemical reagent and thereafter ephedrine, pseudoephedrine or combination thereof is introduced to the anhydrous ammonia to produce a reaction product, the methamphetamine yield in the reaction product is below 50%, preferably below 10%. and more preferably below 1%. Preferred chemical reagents include Fe(III)citrate, ferrocene, 2-chloro-6-(trichloromethyl)pyridine and 1,1,1,2-tetrafluoroethane.Type: ApplicationFiled: December 9, 2002Publication date: March 11, 2004Inventors: George M. Murray, Craig A. Kelly, O. Manuel Uy, Lawrence W. Hunter, David S. Lawrence
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Publication number: 20040014235Abstract: A polymeric food spoilage sensor comprises a polymer containing a polyazamacrocyclic transition metal complex. The complex selectively binds biogenic amines, such as cadaverine, putrescine and histamine, which are released by food spoilage microorganisms. The polymer undergoes a detectable color change upon exposure to biogenic amine, thus indicating that food spoilage has probably occurred. In one embodiment, the polymer is molecularly imprinted with the biogenic amine to impart selective binding affinity. The polymer is easily incorporated in common food containers and can be employed in fiber optic detection devices.Type: ApplicationFiled: July 15, 2003Publication date: January 22, 2004Inventors: Craig A. Kelly, George M. Murray, O. Manuel Uy
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Publication number: 20030143119Abstract: An explosive detector that utilizes an array of molecularly imprinted polymer (MIP) coated, bifurcated fiber optic cables to form an image of a target molecule source. Individual sensor fiber assemblies, each with a calibrated airflow, are used to expose the fibers to the target molecule. The detector energizes a dedicated excitation light source for each fiber, while simultaneously reading and processing the intensity of the resulting fluorescence that is indicative of the concentration of the target molecule. Processing electronics precisely controls the excitation current, and measures the detected signal from each narrow band pass filter and photodiode. A computer with display processes the data to form an image of the target molecule source that can be used to identify the source even when low level contamination of the same molecule is present. The detector can be used to detect multiple and/or non-explosive targets by varying the MIP coating.Type: ApplicationFiled: January 21, 2003Publication date: July 31, 2003Inventors: Paul D. Schwartz, George M. Murray, O. Manuel Uy, Binh Q. Le, David D. Stott, Ark L. Lew, Sharon X. Ling, Joseph J. Suter
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Patent number: 6593142Abstract: A polymeric food spoilage sensor comprises a polymer containing a polyazamacrocyclic transition metal complex. The complex selectively binds biogenic amines, such as cadaverine, putrescine and histamine, which are released by food spoilage microorganisms. The polymer undergoes a detectable color change upon exposure to biogenic amine, thus indicating that food spoilage has probably occurred. In one embodiment, the polymer is molecularly imprinted with the biogenic amine to impart selective binding affinity. The polymer is easily incorporated in common food containers and can be employed in fiber optic detection devices.Type: GrantFiled: October 26, 2001Date of Patent: July 15, 2003Assignee: The Johns Hopkins UniversityInventors: Craig A. Kelly, George M. Murray, O. Manuel Uy
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Publication number: 20030100118Abstract: A polymeric food spoilage sensor comprises a polymer containing a polyazamacrocyclic transition metal complex. The complex selectively binds biogenic amines, such as cadaverine, putrescine and histamine, which are released by food spoilage microorganisms. The polymer undergoes a detectable color change upon exposure to biogenic amine, thus indicating that food spoilage has probably occurred. In one embodiment, the polymer is molecularly imprinted with the biogenic amine to impart selective binding affinity. The polymer is easily incorporated in common food containers and can be employed in fiber optic detection devices.Type: ApplicationFiled: October 26, 2001Publication date: May 29, 2003Inventors: Craig A. Kelly, George M. Murray, O. Manuel Uy
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Publication number: 20020189868Abstract: A controller for a quartz crystal microbalance (QCM) sensor system and method for detecting mass deposition on a QCM sensor. The controller controls a QCM using temperature-, voltage- and current-regulating circuits, a microcontroller, an oscillator, heating and cooling devices and circuits, high voltage grids, digital-to-analog and analog-to-digital converters, data telemetry and uplink circuits, and a remote user. The remote user may be a person, computer, network or data logger. The remote user allows the controller to be reconfigurable during operation. The controller samples and reports data faster and is more reliable over extended periods of operation. Further, the controller is assembled using innovative techniques making it smaller and thus more transportable, easier to incorporate into existing facilities and less expensive to construct and operate. The apparatus may also be assembled in a modular fashion that allows for customization.Type: ApplicationFiled: August 26, 2002Publication date: December 19, 2002Inventors: Russell P. Cain, Bliss G. Carkhuff, O. Manuel Uy
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Patent number: 6492601Abstract: A controller for a quartz crystal microbalance (QCM) sensor system and method for detecting mass deposition on a QCM sensor. The controller controls a QCM using temperature-, voltage- and current-regulating circuits, a microcontroller, an oscillator, heating and cooling devices and circuits, high voltage grids, digital-to-analog and analog-to-digital converters, data telemetry and uplink circuits, and a remote user. The remote user may be a person, computer, network or data logger. The remote user allows the controller to be reconfigurable during operation. The controller samples and reports data faster and is more reliable over extended periods of operation. Further, the controller is assembled using innovative techniques making it smaller and thus more transportable, easier to incorporate into existing facilities and less expensive to construct and operate. The apparatus may also be assembled in a modular fashion that allows for customization.Type: GrantFiled: November 1, 2000Date of Patent: December 10, 2002Assignee: The Johns Hopkins UniversityInventors: Russell P. Cain, Bliss G. Carkhuff, O. Manuel Uy
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Patent number: 4012655Abstract: The adherence of an optically reflective coating of refractory metal oxide particles such as ZrO.sub.2 or Al.sub.2 O.sub.3 on a fused silica discharge tube surface is improved severalfold by an adhesion layer consisting of colloidal aluminum oxide and boric oxide powders. The adhesion layer may be first applied and dried, the refractory metal oxide coating then applied, and the quartz tube then heated to a temperature greater than 460.degree. C., the melting point of boric oxide. The refractory metal oxide particles may also be applied admixed with the colloidal aluminum oxide and the boric oxide. The improved coating strength permits the use of a thicker layer of refractory metal oxide for higher optical and thermal reflection.Type: GrantFiled: August 4, 1975Date of Patent: March 15, 1977Assignee: General Electric CompanyInventors: Charles I. McVey, O. Manuel Uy