Patents by Inventor Oberdan Leo

Oberdan Leo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROPHYLACTIC AND THERAPEUTIC USE OF SIRTUIN INHIBITORS IN TNF-ALPHA MEDIATED PATHOLOGIES
    Publication number: 20100137345
    Abstract: The invention relates to the use of sirtuin inhibitors for reducing TNF-alpha production by cells and organisms. The invention also concerns prophylactic and therapeutic applications of sirtuin inhibitors in TNF-alpha mediated pathologies, such as various inflammatory and autoimmune disorders.
    Type: Application
    Filed: May 14, 2008
    Publication date: June 3, 2010
    Applicant: Universite Libre de Bruxelles
    Inventors: Oberdan Leo, Mara Galli, Frédéric Van Gool
  • NEW METHOD FOR THE TREATMENT OF INFLAMMATORY DISEASES
    Publication number: 20090325923
    Abstract: The present invention relates to the use of an inhibitor of the formation of nicotinamide adenyl dinucleotide for the preparation of a medicament used in the treatment of inflammatory diseases such as rheumatoid arthritis and endotoxemia.
    Type: Application
    Filed: September 3, 2007
    Publication date: December 31, 2009
    Applicant: TOPOTARGET SWITZERLAND SA
    Inventors: Oberdan Leo, Thibaut De Smedt, Frederic Van Gool, Mara Galli
  • Amp-kinase agonists or adenosine pro-drugs as immuno-stimulating agents
    Publication number: 20050002943
    Abstract: The present invention relates to the use of AMP-activated protein kinase (AMP-kinase) agonists or adenosine pro-drugs as immune enhancing compounds, as adjuvants in a vaccine or as anti-inflammatory compounds. The invention further relates to a compositions, vaccines and products comprising an immune response eliciting molecule and an immune response enhancing compound, wherein said immune enhancing compound is chosen from the group of AMP-activated protein kinase (AMP-kinase) agonists or adenosine pro-drugs.
    Type: Application
    Filed: October 30, 2002
    Publication date: January 6, 2005
    Inventors: Oberdan Leo, Erika Baus
  • Dendritic-like cell/tumor cell hybrids and hybridomas for inducing an anti-tumor response
    Publication number: 20010012632
    Abstract: A method produces an anti-tumor response in a mammalian subject in need of anti-tumor treatment. Hybrids of tumor cells with dendritic cells or dendritic-like cells can be administered to the subject. The tumor cell of the hybrid corresponds to the tumor of the subject. Alternatively, autologous immune cells of the subject can be administered in which the immune cells are activated in vitro by co-cultivation with these hybrids.
    Type: Application
    Filed: March 9, 2001
    Publication date: August 9, 2001
    Inventors: Muriel Moser, Oberdan Leo, Laurence Lespagnard, Jacques Urbain, Catherine Bruyns, Catherine Gerard, Michel Goldman, Thierry Velu, Fabienne Willems, Nicole Tasiaux, Jason Perret, AnneMarie Verheyden