Patents by Inventor Octavio Franco

Octavio Franco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptides having anti-senescent effects and uses thereof
    Patent number: 12268746
    Abstract: Polypeptides which can provide a senotherapeutic effect are provided herein. The polypeptides can be formulated for topical application and can be applied topically to a subject to provide a senotherapeutic effect in the subject or in the cells of the subject.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: April 8, 2025
    Assignees: OneSkin, Inc., Universidade Catolica de Brasilia, Uniao Brasileira de Educacao Catolica, Brasilia
    Inventors: Alessandra Zonari, Carolina Reis de Oliveira, Edgar Andres Ochoa, Juliana Lott de Carvalho, Lear Brace, Mariana Boroni, Mylieneth Guiang, Octávio Franco, William Farias Porto, Thuany de Alencar e Silva
  • Polypeptides having anti-senescent effects and uses thereof
    Patent number: 12268747
    Abstract: Polypeptides which can provide a senotherapeutic effect are provided herein. The polypeptides can be formulated for topical application and can be applied topically to a subject to provide a senotherapeutic effect in the subject or in the cells of the subject.
    Type: Grant
    Filed: May 24, 2024
    Date of Patent: April 8, 2025
    Assignees: OneSkin, Inc., Universidade Catolica de Brasilia, Uniao Brasileira de Educacao Catolica, Brasilia
    Inventors: Alessandra Zonari, Carolina Reis de Oliveira, Edgar Andres Ochoa, Juliana Lott de Carvalho, Lear Brace, Mariana Boroni, Mylieneth Guiang, Octávio Franco, William Farias Porto, Thuany de Alencar e Silva
  • POLYPEPTIDES HAVING ANTI-SENESCENT EFFECTS AND USES THEREOF
    Publication number: 20240342290
    Abstract: Polypeptides which can provide a senotherapeutic effect are provided herein. The polypeptides can be formulated for topical application and can be applied topically to a subject to provide a senotherapeutic effect in the subject or in the cells of the subject.
    Type: Application
    Filed: May 24, 2024
    Publication date: October 17, 2024
    Inventors: Alessandra ZONARI, Carolina Reis de OLIVEIRA, Edgar Andres OCHOA, Juliana Lott de CARVALHO, Lear BRACE, Mariana BORONI, Mylieneth GUIANG, Octávio FRANCO, William Farias PORTO, Thuany de Alencar e SILVA
  • COMPUTATIONAL PLATFORM FOR IN SILICO COMBINATORIAL SEQUENCE SPACE EXPLORATION AND ARTIFICIAL EVOLUTION OF PEPTIDES
    Publication number: 20210183469
    Abstract: Disclosed herein are methods of designing peptides having at least one property of interest, such as ?-helical propensity, higher net charge, hydrophobicity, and/or hydrophobic moment. Also disclosed herein are novel artificially evolved peptides (e.g., antimicrobial peptides), which may be designed according to the methods described herein, and methods of use thereof.
    Type: Application
    Filed: March 12, 2019
    Publication date: June 17, 2021
    Applicants: Massachusetts Institute of Technology, Universidade Católica de Brasília
    Inventors: Timothy Kuan-Ta Lu, Cesar De la Fuente Nunez, William Porto, Octavio Franco
  • POLYPEPTIDES HAVING ANTI-SENESCENT EFFECTS AND USES THEREOF
    Publication number: 20210038729
    Abstract: Polypeptides which can provide a senotherapeutic effect are provided herein. The polypeptides can be formulated for topical application and can be applied topically to a subject to provide a senotherapeutic effect in the subject or in the cells of the subject.
    Type: Application
    Filed: July 22, 2020
    Publication date: February 11, 2021
    Inventors: Alessandra ZONARI, Carolina Reis de OLIVEIRA, Edgar Andres OCHOA, Juliana Lott de CARVALHO, Lear BRACE, Mariana BORONI, Mylieneth GUIANG, Octávio FRANCO, William Farias PORTO, Thuany de Alencar e SILVA
  • COMPUTATIONAL PLATFORM FOR IN SILICO COMBINATORIAL SEQUENCE SPACE EXPLORATION AND ARTIFICIAL EVOLUTION OF PEPTIDES
    Publication number: 20190279741
    Abstract: Disclosed herein are methods of designing peptides having at least one property of interest, such as ?-helical propensity, higher net charge, hydrophobicity, and/or hydrophobic moment. Also disclosed herein are novel artificially evolved peptides (e.g., antimicrobial peptides), which may be designed according to the methods described herein, and methods of use thereof.
    Type: Application
    Filed: March 12, 2019
    Publication date: September 12, 2019
    Applicants: Massachusetts Institute of Technology, Universidade Católica de Brasília
    Inventors: Timothy Kuan-Ta Lu, Cesar De la Fuente Nunez, William Porto, Octavio Franco
  • Plant derived antibiotic peptide rich in glycine
    Patent number: 8445428
    Abstract: The present invention relates to a novel peptide extracted from guava (Psidium guajava) seeds, that provides bactericide activity, Preferentially against Gram-negative bacteria which are known to cause urinary, hospital, and intestinal tract infections (Proteus sp. And Klebsiella sp.). The peptide, that has the amino acid sequence RESPSSRMEC YEQAERYGYG GYGGGRYGGG YGSGRGQPVG QGVERSHDDN RNQPR, belongs to the class of glycine rich proteins and has approximately 5 kDa of molecular weight. The invention also relates to antibiotic compositions for human, veterinary and plant treatments. Alternatively, the peptide, or a functionally similar derivative, subjects of the present invention, can be used for transforming organisms aiming pathogen resistance, other adaptive advantages, as well as various properties, specially for plants and animals.
    Type: Grant
    Filed: January 2, 2008
    Date of Patent: May 21, 2013
    Assignees: Uniao Brasiliense de Educacao e Cultura—UBEC, Empresa Brasileira de Pesquisa Agropercuaria—EMBRAPA
    Inventors: Octavio Franco, Patricia Barbosa Pelegrini, Carlos Bloch Junior, Luciano Paulino Silva