Abstract: A closure device for deploying sutures includes a suture, an elongate support, and a suture-positioning support coupled to a distal end portion of the elongate support. The closure device is configured to transition the suture-positioning support from a delivery position to a first deployed position, in which the suture-positioning support laterally extends in a first direction; couple the suture to the suture-positioning support; thereafter, transition the suture-positioning support from the first deployed position back to the delivery position; thereafter, rotate the suture-positioning support, while in the delivery position, about an axis of the elongate support; thereafter, transition the suture-positioning support from the delivery position to a second deployed position, in which the suture-positioning support laterally extends in a second direction; and proximally withdraw the suture from the suture-positioning support while the suture-positioning support is in the second deployed position.

Abstract: A closure device (320) is provided for suturing a puncture. The closure device (320) includes a suture (322, 822), an elongate support (328), a suture-positioning support (330), and an elongate dilator (344). The suture-positioning support (330) is coupled to a distal end portion (332) of the elongate support (328), laterally extendable with respect to the distal end portion (332) of the elongate support (328), and configured to removably receive the suture (322, 822). The dilator (344) is configured to be inserted through the puncture, and has a proximal end (348) that is coupled to the distal end portion (332) of the elongate support (328). The closure device (320) is configured to allow movement of the distal end portion (332) of the elongate support (328) with respect to the proximal end (348) of the dilator (344) with at least two degrees of freedom. Other embodiments are also described.

Abstract: A closure device (320) is provided for suturing a puncture. The closure device (320) includes a suture (322, 822), an elongate support (328), a suture-positioning support (330), and an elongate dilator (344). The suture-positioning support (330) is coupled to a distal end portion (332) of the elongate support (328), laterally extendable with respect to the distal end portion (332) of the elongate support (328), and configured to removably receive the suture (322, 822). The dilator (344) is configured to be inserted through the puncture, and has a proximal end (348) that is coupled to the distal end portion (332) of the elongate support (328). The closure device (320) is configured to allow movement of the distal end portion (332) of the elongate support (328) with respect to the proximal end (348) of the dilator (344) with at least two degrees of freedom. Other embodiments are also described.

Abstract: A device for implanting radiotherapy seeds in a tumor. The device includes a delivery tube having a distal end designed to enter the tumor, and defining an internal channel and an elongate applicator carrying one or more radiotherapy seeds each having a length of at least 1 millimeter, the applicator passing through the internal channel of the delivery tube. When a distal end of the elongate applicator is near a distal end of the delivery tube, it assumes an angle relative to an axis of the delivery tube, such that seeds ejected from the elongate applicator enter the tumor at an angle relative to the axis of the delivery tube.

Abstract: A closure device (320) is provided for suturing a puncture. The closure device (320) includes a suture (322, 822), an elongate support (328), a suture-positioning support (330), and an elongate dilator (344). The suture-positioning support (330) is coupled to a distal end portion (332) of the elongate support (328), laterally extendable with respect to the distal end portion (332) of the elongate support (328), and configured to removably receive the suture (322, 822). The dilator (344) is configured to be inserted through the puncture, and has a proximal end (348) that is coupled to the distal end portion (332) of the elongate support (328). The closure device (320) is configured to allow movement of the distal end portion (332) of the elongate support (328) with respect to the proximal end (348) of the dilator (344) with at least two degrees of freedom. Other embodiments are also described.

Abstract: A device for implanting radiotherapy seeds in a tumor. The device includes a delivery tube having a distal end designed to enter the tumor, and defining an internal channel and an elongate applicator carrying one or more radiotherapy seeds each having a length of at least 1 millimeter, the applicator passing through the internal channel of the delivery tube. When a distal end of the elongate applicator is near a distal end of the delivery tube, it assumes an angle relative to an axis of the delivery tube, such that seeds ejected from the elongate applicator enter the tumor at an angle relative to the axis of the delivery tube.