Patents by Inventor Odile Leclerc

Odile Leclerc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azabicycloalkane derivatives, preparation thereof and use thereof in therapy
    Patent number: 8759343
    Abstract: The invention relates to compounds of the general formula (I): wherein R, m, n and o are as defined herein. The invention also relates to a method for preparing the same and to the application in therapy.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: June 24, 2014
    Assignee: Sanofi
    Inventors: Omar Ben Ayad, Odile LeClerc, Alistair Lochead, Mourad Saady, Franck Slowinski, Julien Vache
  • Derivatives of 5-pyridazinyl-1-azabicyclo[3.2.1]octane, preparation method thereof and use of same in therapeutics
    Patent number: 8557819
    Abstract: The invention relates to compounds having general formula (I), wherein R is as defined herein. The invention also relates to acid addition salt, a hydrate or a solvate of compounds of formula (I). The invention further relates to the method of preparing said compounds and to the use of same in therapeutics.
    Type: Grant
    Filed: November 1, 2011
    Date of Patent: October 15, 2013
    Assignee: Sanofi
    Inventors: Frederic Galli, Odile Leclerc, Alistair Lochead, Julien Vache
  • Derivatives of 5-pyridinyl-1-azabicyclo[3.2.1]octane, preparation method thereof and use of same in therapeutics
    Patent number: 8541440
    Abstract: The invention relates to compounds having general formula (I), wherein R is as defined herein. The invention also relates to acid addition salt, a hydrate or a solvate of compounds of formula (I). The invention further relates to the method of preparing said compounds and to the use of same in therapeutics.
    Type: Grant
    Filed: November 29, 2010
    Date of Patent: September 24, 2013
    Assignee: Sanofi
    Inventors: Frederic Galli, Odile Leclerc, Alistair Lochead, Julien Vache
  • 1,4-diazabicyclo[3.2.2]nonanecarboxamide derivatives, preparation and therapeutic use thereof
    Patent number: 8524706
    Abstract: The present invention discloses and claims compounds of general formula in which X, R1, P, Q, R and W are as described herein. The compounds of the invention are useful in a variety of therapeutic applications.
    Type: Grant
    Filed: October 27, 2008
    Date of Patent: September 3, 2013
    Assignee: Sanofi
    Inventors: Frederic Galli, Patrick Lardenois, Odile Leclerc, Alistair Lochead
  • N-azabicyclic carboxamide derivatives, preparation thereof and therapeutic use thereof
    Patent number: 8394820
    Abstract: This disclosure relates to compounds of formula (I): wherein X1, X2, X3, X4, n, Y, W, and A are as defined in the disclosure, or a salt thereof, or a hydrate or solvate thereof, and to processes for the preparation of these compounds and the therapeutic use thereof.
    Type: Grant
    Filed: July 21, 2010
    Date of Patent: March 12, 2013
    Assignee: Sanofi
    Inventors: Laurent Dubois, Yannick Evanno, André Malanda, Odile LeClerc
  • AZABICYCLOALKANE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN THERAPY
    Publication number: 20120202807
    Abstract: The invention relates to compounds of the general formula (I): wherein R, m, n and o are as defined herein. The invention also relates to a method for preparing the same and to the application in therapy.
    Type: Application
    Filed: March 16, 2012
    Publication date: August 9, 2012
    Applicant: SANOFI
    Inventors: Omar Ben AYAD, Odile LECLERC, Alistair LOCHEAD, Mourad SAADY, Franck SLOWINSKI, Julien VACHE
  • Azabicycloalkane derivatives, preparation thereof and use thereof in therapy
    Patent number: 8173669
    Abstract: The invention relates to compounds of the general formula (I): Wherein R, m, n and o are as defined herein. The invention also relates to a method for preparing the same and to the application in therapy.
    Type: Grant
    Filed: August 4, 2009
    Date of Patent: May 8, 2012
    Assignee: Sanofi-Aventis
    Inventors: Omar Ben Ayad, Odile Leclerc, Alistair Lochead, Mourad Saady, Franck Slowinski, Julien Vache
  • DERIVATIVES OF 5-PYRIDAZINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS
    Publication number: 20120046298
    Abstract: The invention relates to compounds having general formula (I), wherein R is as defined herein. The invention also relates to acid addition salt, a hydrate or a solvate of compounds of formula (I). The invention further relates to the method of preparing said compounds and to the use of same in therapeutics.
    Type: Application
    Filed: November 1, 2011
    Publication date: February 23, 2012
    Applicant: SANOFI-AVENTIS
    Inventors: Frederic GALLI, Odile LECLERC, Alistair LOCHEAD, Julien VACHE
  • Derivatives of 5-pyridazinyl-1-azabicyclo[3.2.1]octane, preparation method thereof and use of same in therapeutics
    Patent number: 8076340
    Abstract: The invention relates to compounds having general formula (I), wherein R is as defined herein. The invention also relates to acid addition salt, a hydrate or a solvate of compounds of formula (I). The invention further relates to the method of preparing said compounds and to the use of same in therapeutics.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: December 13, 2011
    Assignee: Sanofi-Aventis
    Inventors: Frederic Galli, Odile Leclerc, Alistair Lochead, Julien Vache
  • DERIVATIVES OF 5-PYRIDINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS
    Publication number: 20110077264
    Abstract: The invention relates to compounds having general formula (I), wherein R is as defined herein. The invention also relates to acid addition salt, a hydrate or a solvate of compounds of formula (I). The invention further relates to the method of preparing said compounds and to the use of same in therapeutics.
    Type: Application
    Filed: November 29, 2010
    Publication date: March 31, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Frederic GALLI, Odile LECLERC, Alistair LOCHEAD, Julien VACHE
  • N-AZABICYCLIC CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
    Publication number: 20110009444
    Abstract: This disclosure relates to compounds of formula (I): wherein X1, X2, X3, X4, n, Y, W, and A are as defined in the disclosure, or a salt thereof, or a hydrate or solvate thereof, and to processes for the preparation of these compounds and the therapeutic use thereof.
    Type: Application
    Filed: July 21, 2010
    Publication date: January 13, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, André MALANDA, Odile LECLERC
  • Derivatives of 5-pyridinyl-1-azabicyclo[3.2.1]octane, preparation method thereof and use of same in therapeutics
    Patent number: 7863290
    Abstract: The invention relates to compounds having general formula (I), wherein R is as defined herein. The invention also relates to acid addition salt, a hydrate or a solvate of compounds of formula (I). The invention further relates to the method of preparing said compounds and to the use of same in therapeutics.
    Type: Grant
    Filed: February 11, 2008
    Date of Patent: January 4, 2011
    Assignee: sanofi-aventis
    Inventors: Frederic Galli, Odile LeClerc, Alistair Lochead, Julien Vache
  • AZABICYCLOALKANE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN THERAPY
    Publication number: 20100035916
    Abstract: The invention relates to compounds of the general formula (I): Wherein R, m, n and o are as defined herein. The invention also relates to a method for preparing the same and to the application in therapy.
    Type: Application
    Filed: August 4, 2009
    Publication date: February 11, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Omar BEN AYAD, Odile LECLERC, Alistair LOCHEAD, Mourad SAADY, Franck SLOWINSKI, Julien VACHE
  • Derivatives of 1,4-diazabicyclo[3.2.1]octanecarboxamide, preparation method thereof and use of same in therapeutics
    Patent number: 7589201
    Abstract: The invention relates to a compound of formula (I): Wherein R1, X, P, Q, R and W are as defined herein. The invention also relates to the use of same in therapeutics.
    Type: Grant
    Filed: July 10, 2006
    Date of Patent: September 15, 2009
    Assignee: Sanofi-Aventis
    Inventors: Frederic Galli, Odile LeClerc, Alistair Lochead
  • Derivatives of 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, their preparation and their therapeutic application
    Patent number: 7585974
    Abstract: Compounds complying with the general formula in which R either represents a halogen atom or a phenyl group substituted by one or more groups chosen from halogen atoms and (C1-C6)alkyl, (C1-C6)alkoxy, nitro, amino, trifluoromethyl, cyano, hydroxy, acetyl or methylenedioxy groups, or represents a pyridinyl group, a thienyl group, an indolyl group, or a pyrimidinyl group optionally substituted by one or more (C1-C6)alkoxy groups, where, of the two carbon-carbon bonds represented by , one is single and the other may be single or double. The compounds of this invention are useful as therapeutic agents.
    Type: Grant
    Filed: April 5, 2007
    Date of Patent: September 8, 2009
    Assignee: Sanofi-Aventis
    Inventors: Frederic Galli, Odile LeClerc, Alistair Lochead, Alain Nedelec
  • DERIVATIVES OF 5-PYRIDAZINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS
    Publication number: 20090088440
    Abstract: The invention relates to compounds having general formula (I), wherein R is as defined herein. The invention also relates to acid addition salt, a hydrate or a solvate of compounds of formula (I). The invention further relates to the method of preparing said compounds and to the use of same in therapeutics.
    Type: Application
    Filed: December 5, 2008
    Publication date: April 2, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Frederic Galli, Odile Leclerc, Alistair Lochead, Julien Vache
  • 1,4-Diazabicyclo[3.2.2]nonanecarboxamide Derivatives, Preparation and Therapeutic Use Thereof
    Publication number: 20090054416
    Abstract: The present invention discloses and claims compounds of general formula in which X, R1, P, Q, R and W are as described herein. The compounds of the invention are useful in a variety of therapeutic applications.
    Type: Application
    Filed: October 27, 2008
    Publication date: February 26, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Frederic GALLI, Patrick LARDENOIS, Odile LECLERC, Alistair LOCHEAD
  • Derivatives of 5-pyridazinyl-1-azabicyclo[3.2.1]octane, preparation method thereof and use of same in therapeutics
    Patent number: 7476674
    Abstract: The invention relates to compounds having general formula (I), wherein R is as defined herein. The invention also relates to acid addition salt, a hydrate or a solvate of compounds of formula (I). The invention further relates to the method of preparing said compounds and to the use of same in therapeutics.
    Type: Grant
    Filed: February 11, 2008
    Date of Patent: January 13, 2009
    Assignee: Sanofi-Aventis
    Inventors: Frederic Galli, Odile Leclerc, Alistair Lochead, Julien Vache
  • 1,4-Diazabicyclo[3.2.2]nonanecarboxamide derivatives, preparation and therapeutic use thereof
    Patent number: 7456171
    Abstract: The present invention discloses and claims compounds of general formula in which X represents a nitrogen atom or a group of formula C—R2, P represents a group of formula C—R3, Q represents a group of formula C—R4, R represents a group of formula C—R5, W represents a group of formula C—R6, or one of the symbols P, Q, R and W represents a nitrogen atom, R1 represents a hydrogen atom or an alkyl group, R2 represents a hydrogen atom or an alkyl group, R3, R4, R5 and R6 each represent a hydrogen or halogen atom, or an alkyl, alkoxy, nitro, amino, trifluoromethyl, cyano or amino group or other functional groups. The compounds of the invention are useful in a variety of therapeutic applications.
    Type: Grant
    Filed: April 4, 2005
    Date of Patent: November 25, 2008
    Assignee: Sanofi-Aventis
    Inventors: Frederic Galli, Patrick Lardenois, Odile Leclerc, Alistair Lochead
  • DERIVATIVES OF 5-PYRIDAZINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS
    Publication number: 20080176855
    Abstract: The invention relates to compounds having general formula (I), wherein R is as defined herein. The invention also relates to acid addition salt, a hydrate or a solvate of compounds of formula (I). The invention further relates to the method of preparing said compounds and to the use of same in therapeutics.
    Type: Application
    Filed: February 11, 2008
    Publication date: July 24, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Frederic GALLI, Odile LECLERC, Alistair LOCHEAD, Julien VACHE