Patents by Inventor Odile Siffert

Odile Siffert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4898815
    Abstract: The invention provides a synthetic peptide which reproduces at least 5 of the 11 amino acids common to the .gamma. chain of sub-unit A of cholera toxin and the .gamma. chain of LT toxin of Escherichia coli. It is preferably constituted by a pentadecapeptide which corresponds to the following formula (I): ##STR1## The process of synthesis is by the step by step construction of the peptide chain starting from the C terminal end of said chain, by the successive fixing of the amino acids which constitute the latter. A novel medicament for the treatment of cholera and infectious gastro-enterites comprises said synthetic peptide as active constituent. A diagnosis agent for cholera and/or infectious gastro-enterites comprises a sequence of nucleotides corresponding to the 5 minimum amino acids of the synthetic peptide.
    Type: Grant
    Filed: January 20, 1987
    Date of Patent: February 6, 1990
    Assignee: Institut Pasteur
    Inventors: Andre Dodin, Odile Siffert, Georgette Le Thuillier, Patrice Allard
  • Patent number: 4686281
    Abstract: The invention provides a synthetic peptide comprising at least 5 of the 11 amino acids common to the .gamma.chain of sub-unit A of the cholera toxin and the .gamma.chain of the LT toxin of Escherichia coli. The peptide is preferably constituted by a pentadecapeptide which corresponds to the following formula (I): ##STR1## The process of synthesis is by the step by step construction of the peptide chain starting form the C terminal end of said chain, by the successive fixing of the amino acids which constitute the peptide. A novel medicament for the treatment of cholera and infectious gastro-enterites is also disclosed which comprises said synthetic peptide as an active constituent. A diagnosis agent for cholera and/or infectious gastroenterites comprises a sequence of at least the 5 amino acids of the synthetic peptide.
    Type: Grant
    Filed: August 24, 1984
    Date of Patent: August 11, 1987
    Assignee: Institut Pasteur
    Inventors: Andre Dodin, Odile Siffert, Georgette Le Thuillier, Patrice Allard