Patents by Inventor Odunayo Omolola Boluwarin MUGISHO

Odunayo Omolola Boluwarin MUGISHO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYTOKINE MODULATION
    Publication number: 20220288163
    Abstract: The inventions relate to the use of hemichannel blockers to modulate cytokine levels in a subject, including the angiogenic cytokine, VEGF, and their production, secretion and/or release, and to the use of hemichannel blockers to reduce or level cytokine activity, including in conditions characterized in whole or in part by angiogenesis and/or vessel leak.
    Type: Application
    Filed: May 27, 2022
    Publication date: September 15, 2022
    Inventors: Colin Richard GREEN, Odunayo Omolola Boluwarin MUGISHO, Bradford James DUFT
  • COMPOSITIONS AND METHODS FOR MODULATING EPITHELIAL-MESENCHYMAL TRANSITION
    Publication number: 20220280473
    Abstract: The inventions relate to the use of anti-hemichannel compounds, including anti-connexin 43 hemichannel opening compounds, inhibitors and blockers, to modulate, suppress and stabilize epithelial-mesenchymal and/or endothelial-mesenchymal transition in diseases, disorders and conditions, including fibrotic diseases, disorders and conditions and other conditions associated with fibrosis.
    Type: Application
    Filed: March 2, 2022
    Publication date: September 8, 2022
    Inventors: Colin Richard GREEN, Odunayo Omolola Boluwarin MUGISHO, Brian LEVY
  • Cytokine modulation
    Patent number: 11344603
    Abstract: The inventions relate to the use of hemichannel blockers to modulate cytokine levels in a subject, including the angiogenic cytokine, VEGF, and their production, secretion and/or release, and to the use of hemichannel blockers to reduce or level cytokine activity, including in conditions characterized in whole or in part by angiogenesis and/or vessel leak.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: May 31, 2022
    Assignees: AUCKLAND UNISERVICES LIMITED, OCUNEXUS THERAPEUTICS, INC.
    Inventors: Colin Richard Green, Odunayo Omolola Boluwarin Mugisho, Bradford James Duft
  • COMPOSITIONS AND METHODS FOR PROTECTING EPITHELIAL AND BARRIER INTEGRITY
    Publication number: 20210000911
    Abstract: The inventions relate to the use of hemichannel blockers to modulate BRB integrity and function, RPE integrity and function, tight junction integrity and function, ZO-1 internalization, gap junction internalization, and/or type IV collagen levels in a subject.
    Type: Application
    Filed: April 23, 2020
    Publication date: January 7, 2021
    Inventors: Odunayo Omolola Boluwarin MUGISHO, Colin Richard GREEN, Bradford James DUFT
  • CYTOKINE MODULATION
    Publication number: 20190030122
    Abstract: The inventions relate to the use of hemichannel blockers to modulate cytokine levels in a subject, including the angiogenic cytokine, VEGF, and their production, secretion and/or release, and to the use of hemichannel blockers to reduce or level cytokine activity, including in conditions characterized in whole or in part by angiogenesis and/or vessel leak.
    Type: Application
    Filed: July 19, 2018
    Publication date: January 31, 2019
    Inventors: Colin Richard GREEN, Odunayo Omolola Boluwarin MUGISHO, Bradford James DUFT