Patents by Inventor Ofer Reany

Ofer Reany has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing and isolating -bicalutamide and its intermediates
    Patent number: 7102026
    Abstract: The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio) propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof. The present invention further discloses a new process for the isolation and purification of racemic and optically active bicalutamide.
    Type: Grant
    Filed: June 25, 2003
    Date of Patent: September 5, 2006
    Assignee: TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság
    Inventors: Ben-Zion Dolitzky, Ofer Reany, Jenny Shammai
  • Novel process for preparing rac-bicalutamide and its intermediates
    Publication number: 20050090682
    Abstract: The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting-from-ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio) propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof.
    Type: Application
    Filed: November 23, 2004
    Publication date: April 28, 2005
    Inventors: Ben-Zion Dolitzky, Ofer Reany, Jenny Shammai
  • Process for preparing rac-bicalutamide and its intermediates
    Patent number: 6861557
    Abstract: The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio) propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: March 1, 2005
    Assignee: Biogal Gyógyszergyár Rt.
    Inventors: Ben-Zion Dolitzky, Ofer Reany, Jenny Shammai
  • Process for preparing rac-bicalutamide and its intermediates
    Patent number: 6849763
    Abstract: The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone)]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio) propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: February 1, 2005
    Assignee: Biogal Gyógyszergyár Rt.
    Inventors: Ben-Zion Dolitzky, Ofer Reany, Jenny Shammai
  • Process for preparing rac-bicalutamide and its intermediates
    Patent number: 6797843
    Abstract: The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio) propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof.
    Type: Grant
    Filed: September 22, 2003
    Date of Patent: September 28, 2004
    Assignee: Biogal Gyógyszergyár Rt.
    Inventors: Ben-Zion Dolitzky, Ofer Reany, Jenny Shammai
  • Novel process for preparing rac-bicalutamide and its intermediates
    Publication number: 20040176638
    Abstract: The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio)propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof.
    Type: Application
    Filed: March 8, 2004
    Publication date: September 9, 2004
    Inventors: Ben-Zion Dolitzky, Ofer Reany, Jenny Shammai
  • Novel process for preparing rac-bicalutamide and its intermediates
    Publication number: 20040176633
    Abstract: The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio) propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof.
    Type: Application
    Filed: March 8, 2004
    Publication date: September 9, 2004
    Inventors: Ben-Zion Dolitzky, Ofer Reany, Jenny Shammai
  • Novel process for preparing rac-bicalutamide and its intermediates
    Publication number: 20040167349
    Abstract: The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio) propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof.
    Type: Application
    Filed: March 1, 2004
    Publication date: August 26, 2004
    Inventors: Ben-Zion Dolitzky, Ofer Reany, Jenny Shammai
  • Crystalline solid famciclovir forms I, II, III and preparation thereof
    Publication number: 20040097528
    Abstract: The present invention provides novel crystalline solid anhydrous forms of famciclovir, denominated form I, II and III, as well as their preparations thereof.
    Type: Application
    Filed: August 26, 2003
    Publication date: May 20, 2004
    Inventors: Ben-Zion Dolitzky, Shlomit Wizel, Ofer Reany, Jenny Shammai
  • Process for preparing rac-bicalutamide and its intermediates
    Patent number: 6737550
    Abstract: The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio) propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof.
    Type: Grant
    Filed: June 13, 2002
    Date of Patent: May 18, 2004
    Assignee: Biogal Gryogyszergyar Rt.
    Inventors: Ben-Zion Dolitzky, Ofer Reany, Jenny Shammai
  • Novel process for preparing rac-bicalutamide and its intermediates
    Publication number: 20040059147
    Abstract: The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio) propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof.
    Type: Application
    Filed: September 22, 2003
    Publication date: March 25, 2004
    Inventors: Ben-Zion Dolitzky, Ofer Reany, Jenny Shammai
  • Novel process for preparing and isolating rac-bicalutamide and its intermediates
    Publication number: 20040044249
    Abstract: The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio) propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof. The present invention further discloses a new process for the isolation and purification of racemic and optically active bicalutamide.
    Type: Application
    Filed: June 25, 2003
    Publication date: March 4, 2004
    Inventors: Ben-Zion Dolitzky, Ofer Reany, Jenny Shammai
  • Novel process for preparing rac-bicalutamide and its intermediates
    Publication number: 20030045741
    Abstract: The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio)propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof.
    Type: Application
    Filed: June 13, 2002
    Publication date: March 6, 2003
    Inventors: Ben-Zion Dolitzky, Ofer Reany, Jenny Shammai