Patents by Inventor Ofer Sadan

Ofer Sadan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mesenchymal stem cells for the treatment of CNS diseases
    Patent number: 11185572
    Abstract: An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: November 30, 2021
    Assignees: Ramot at Tel-Aviv University Ltd., BrainStorm Ceil Therapeutics Ltd.
    Inventors: Avinoam Kadouri, Avihay Bar-Ilan, Eldad Melamed, Daniel Offen, Ofer Sadan, Merav Bahat-Stromza
  • MESENCHYMAL STEM CELLS FOR THE TREATMENT OF CNS DISEASES
    Publication number: 20180333458
    Abstract: An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
    Type: Application
    Filed: July 27, 2018
    Publication date: November 22, 2018
    Applicants: Ramot at Tel-Aviv University Ltd., BrainStorm Cell Therapeutics Ltd.
    Inventors: Avinoam KADOURI, Avihay BAR-ILAN, Eldad MELAMED, Daniel OFFEN, Ofer SADAN, Merav BAHAT-STROMZA
  • Mesenchymal stem cells for the treatment of CNS diseases
    Patent number: 10052363
    Abstract: An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
    Type: Grant
    Filed: September 11, 2016
    Date of Patent: August 21, 2018
    Assignees: Ramot at Tel-Aviv University Ltd., Brainstorm Cell Therapeutics Ltd.
    Inventors: Avinoam Kadouri, Avihay Bar-Ilan, Eldad Melamed, Daniel Offen, Ofer Sadan, Merav Bahat-Stromza
  • MESENCHYMAL STEM CELLS FOR THE TREATMENT OF CNS DISEASES
    Publication number: 20160375098
    Abstract: An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
    Type: Application
    Filed: September 11, 2016
    Publication date: December 29, 2016
    Applicants: Ramot at Tel-Aviv University Ltd., BrainStorm Cell Therapeutics Ltd.
    Inventors: Avinoam KADOURI, Avihay BAR-ILAN, Eldad MELAMED, Daniel OFFEN, Ofer SADAN, Merav BAHAT-STROMZA
  • Mesenchymal stem cells for the treatment of CNS diseases
    Patent number: 9474787
    Abstract: An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: October 25, 2016
    Assignees: Ramot at Tel-Aviv University Ltd., BrainStorm Cell Therapeutics Ltd.
    Inventors: Avinoam Kadouri, Avihay Bar-Ilan, Eldad Melamed, Daniel Offen, Ofer Sadan, Merav Bahat-Stromza
  • MESENCHYMAL STEM CELLS FOR THE TREATMENT OF CNS DISEASES
    Publication number: 20150086517
    Abstract: An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
    Type: Application
    Filed: December 1, 2014
    Publication date: March 26, 2015
    Inventors: Avinoam Kadouri, Avihay Bar-Ilan, Eldad Melamed, Daniel Offen, Ofer Sadan, Merav Bahat-Stromza
  • Mesenchymal stem cells for the treatment of CNS diseases
    Patent number: 8900574
    Abstract: An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: December 2, 2014
    Assignees: Ramot at Tel-Aviv University Ltd., BrainStorm Cell Therapeutics Ltd.
    Inventors: Avinoam Kadouri, Avihay Bar-Ilan, Eldad Melamed, Daniel Offen, Ofer Sadan, Merav Bahat-Stromza
  • MESENCHYMAL STEM CELLS FOR THE TREATMENT OF CNS DISEASES
    Publication number: 20140140968
    Abstract: An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
    Type: Application
    Filed: January 27, 2014
    Publication date: May 22, 2014
    Applicants: BrainStorm Cell Therapeutics Ltd., Ramot at Tel-Aviv University Ltd.
    Inventors: Avinoam KADOURI, Avihay BAR-ILAN, Eldad MELAMED, Daniel OFFEN, Ofer SADAN, Merav BAHAT-STROMZA
  • Mesenchymal stem cells for the treatment of CNS diseases
    Patent number: 8663987
    Abstract: An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
    Type: Grant
    Filed: May 26, 2009
    Date of Patent: March 4, 2014
    Assignees: Ramot at Tel-Aviv University Ltd., BrainStorm Cell Therapeutics Ltd.
    Inventors: Avinoam Kadouri, Avihay Bar-Ilan, Eldad Melamed, Daniel Offen, Ofer Sadan, Merav Bahat-Stromza
  • MESENCHYMAL STEM CELLS FOR THE TREATMENT OF CNS DISEASES
    Publication number: 20120009673
    Abstract: An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
    Type: Application
    Filed: May 26, 2009
    Publication date: January 12, 2012
    Applicants: BrainStorm Cell Therapeutics Inc., RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Avinoam Kadouri, Avihay Bar-llan, Eidad Melamed, Daniel Offen, Ofer Sadan, Merav Bahat-Stromza