Abstract: A system is provided for use with a subject suffering from cancer that includes one or more primary or metastatic solid tumors. The system includes nanoparticles including a magnetic metallic core and a phase-change material (PCM) that surrounds the magnetic metallic core and is configured to absorb latent heat of fusion by undergoing a phase change that occurs at a phase-change temperature of 42-80 degrees C. A radiofrequency (RF) transmitter is configured to transmit energy, in a pulse train alternating between high power and low power at a pulse frequency of 1 Hz-5 Hz, to at least a portion of the subject's body, such so that the nanoparticles are heated to the phase-change temperature of the PCM, and store energy from the pulse train in the PCM as latent heat of fusion. Other embodiments are also described.

Abstract: A system is provided for use with a subject suffering from cancer that includes one or more primary or metastatic solid tumors. The system includes nanoparticles including a magnetic metallic core and a phase-change material (PCM) that surrounds the magnetic metallic core and is configured to absorb latent heat of fusion by undergoing a phase change that occurs at a phase-change temperature of 42-80 degrees C. A radiofrequency (RF) transmitter is configured to transmit energy, in a pulse train alternating between high power and low power at a pulse frequency of 1 Hz-5 Hz, to at least a portion of the subject's body, such so that the nanoparticles are heated to the phase-change temperature of the PCM, and store energy from the pulse train in the PCM as latent heat of fusion. Other embodiments are also described.

Abstract: A method for circuit design includes providing one or more wrapper cells for use with a library of standard cells in design of an IC. Each wrapper cell has geometrical dimensions matching a corresponding group of one or more of the standard cells and defines an electrical path, including at least one via, from a location of a terminal in a lower metal layer in the standard cells in the corresponding group to a location in an upper metal layer. A computerized place-and-route tool receives a layout of the IC including a wrapper cell superimposed over one of the standard cells in the corresponding group. The place-and-route tool automatically routes a signal connection through the upper metal layer and the at least one via defined by the superimposed wrapper cell to the predefined signal terminal in the lower metal layer in the one of the standard cells.

Abstract: A method for circuit design includes providing one or more wrapper cells for use with a library of standard cells in design of an IC. Each wrapper cell has geometrical dimensions matching a corresponding group of one or more of the standard cells and defines an electrical path, including at least one via, from a location of a terminal in a lower metal layer in the standard cells in the corresponding group to a location in an upper metal layer. A computerized place-and-route tool receives a layout of the IC including a wrapper cell superimposed over one of the standard cells in the corresponding group. The place-and-route tool automatically routes a signal connection through the upper metal layer and the at least one via defined by the superimposed wrapper cell to the predefined signal terminal in the lower metal layer in the one of the standard cells.