Abstract: The present invention relates to long-acting insulin analogues having an increased in vivo half-life in which the amino acid at position 22 of the B-chain of native insulin is substituted and one or more amino acids of the A-chain or B-chain of native insulin are additionally substituted, and to long-acting insulin analogue derivatives having a further increased in vivo half-life in which an albumin-binding domain is additionally fused to the long-acting insulin analogues. The insulin analogues or insulin analogue derivatives according to the present invention have a significantly increased in vivo half-life, and thus can provide convenience to diabetic patients who self-administer insulin by injection.

Abstract: The present invention relates to long-acting insulin analogues having an increased in vivo half-life in which the amino acid at position 22 of the B-chain of native insulin is substituted and one or more amino acids of the A-chain or B-chain of native insulin are additionally substituted, and to long-acting insulin analogue derivatives having a further increased in vivo half-life in which an albumin-binding domain is additionally fused to the long-acting insulin analogues. The insulin analogues or insulin analogue derivatives according to the present invention have a significantly increased in vivo half-life, and thus can provide convenience to diabetic patients who self-administer insulin by injection.

Abstract: Provided is a space implementation method and, more particularly, a space implementation method which identically implements, in a user's space, acoustic contents such as music and sound, visual contents such as photos, drama and movies, and other contents such as scent and feel which are being implemented in the space of another user such as a family member, a lover, a friend or an entertainer, thereby forming connectedness between family members or lovers who are in different places, or enabling the user to share event contents enjoyed by entertainers who the user likes.

Abstract: The present invention relates to a space implementation method and, more particularly, to a space implementation method which identically implements, in a user's space, acoustic contents such as music and sound, visual contents such as photos, drama and movies, and other contents such as scent and feel which are being implemented in the space of another user such as a family member, a lover, a friend or an entertainer, thereby forming connectedness between family members or lovers who are in different places, or enabling the user to share event contents enjoyed by entertainers who the user likes.

Abstract: The present invention relates to a method for recognizing multiple user actions and, more particularly, provided is a method capable of recognizing multiple user actions from a collected sound source when multiple actions are performed in a specific space, and accurately determining a user situation from the recognized multiple user actions.

Abstract: The present invention relates to a health care method using a light therapy device and an auxiliary therapy device, the health care method can relax the mind and body of a user by controlling the light therapy device and the auxiliary therapy device on the basis of a user's condition or changes in the user's condition, and accessorily, the mental state of the user.

Abstract: The present invention relates to a system for determining a user psychology index based on user situation information and user profile information and recommending an advice needed for a user according to the determined psychology index. The advice recommendation system according to the present invention determines a user psychology index based on user situation information and user profile information, and the advice recommendation system may correctly diagnose a psychological state of a user and recommend suitable advice for overcoming the diagnosed psychological state. In addition, the advice recommendation system according to the present invention periodically collects user situation information and determines personalized tendency of a user toward the collected user situation information, and thus the advice recommendation system may correctly recommend personalized advice to the user.

Abstract: The present invention relates to a method for recommending a service in a ubiquitous environment in which various services are provided, and more particularly, to a method and system for determining a service required for a user based on situation information of a target user, and recommending, to the target user, an individual service satisfying a service index of the target user with respect to the determined service, or a combined and highly complementary service.

Abstract: Disclosed are a method of producing a target protein in a biologically-active, soluble form in prokaryotic cells and polycistronic vectors therefor.