Patents by Inventor Ok-Hee Chai

Ok-Hee Chai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10016475
    Abstract: The present invention provides a composition for preventing, improving, or treating Th1-mediated immune diseases or Th2-mediated immune diseases, an antihistamine composition, and an anti-inflammatory composition. The present invention provides a method for preventing, improving, or treating Th1-mediated immune diseases or Th2-mediated immune diseases, a method for inhibiting the release of histamine, and a method for preventing, improving, or treating inflammatory disorders. The composition according to the present invention has excellent inhibitory activities for IL-4 generation, the degranulation of mast cells, COX-2, 15-NOX, and the passing of allergens from through an intestinal epithelial cell layer, or an excellent Treg cell inducing activity.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: July 10, 2018
    Assignee: KOREA FOOD RESEARCH INSTITUTE
    Inventors: Dong-Hwa Shon, Hee-Soon Shin, Min-Jung Bae, Ok-Hee Chai, Chang-Yuil Kang, Dae-Woon Choi, Gye-Young Choi, Jeong-Hae Rho, Jeong-Ryong Do
  • Publication number: 20150118266
    Abstract: The present invention provides a composition for preventing, improving, or treating Th1-mediated immune diseases or Th2-mediated immune diseases, an antihistamine composition, and an anti-inflammatory composition. The present invention provides a method for preventing, improving, or treating Th1-mediated immune diseases or Th2-mediated immune diseases, a method for inhibiting the release of histamine, and a method for preventing, improving, or treating inflammatory disorders. The composition according to the present invention has excellent inhibitory activities for IL-4 generation, the degranulation of mast cells, COX-2, 15-NOX, and the passing of allergens from through an intestinal epithelial cell layer, or an excellent Treg cell inducing activity.
    Type: Application
    Filed: May 29, 2013
    Publication date: April 30, 2015
    Applicant: KOREA FOOD RESEARCH INSTITUTE
    Inventors: Dong-Hwa Shon, Hee-Soon Shin, Min-Jung Bae, Ok-Hee Chai, Chang-Yuil Kang, Dae-Woon Choi, Gye-Young Choi, Jeong-Hae Rho, Jeong-Ryong Do
  • Publication number: 20070166405
    Abstract: The present invention relates to an extract of Houttuynia cordata and Rubus coreanus, and a composition for the prevention and treatment of allergic diseases, comprising the same. The inventive extract and the composition comprising the same have the effect of preventing and treating allergic diseases by inhibiting the degranulation and histamine release of mast cells. Also, they show no cytotoxicity and thus can be safely use in vivo.
    Type: Application
    Filed: February 4, 2005
    Publication date: July 19, 2007
    Applicants: REGEN BIOTECH INC.
    Inventors: Chang-Ho Song, Ok-Hee Chai, Yong-In Park, Dong-Sin Lee