Abstract: The invention relates to a method for preparing primed seed, a method for improving the germination rate of seed, and a use of a gaseous composition. The method for preparing primed seed comprises successively: providing seed that is capable of germinating, exposing said seed to a treatment atmosphere for an exposure time of at least 1 second, wherein the treatment atmosphere has a relative humidity of 50% or more and a temperature of 50-100° C., and wherein the exposure time has a duration of 30 minutes or less, and cooling and optionally drying said seed.

Abstract: The invention relates to a method for preparing primed seed, a method for improving the germination rate of seed, and a use of a gaseous composition. The method for preparing primed seed comprises successively: providing seed that is capable of germinating, exposing said seed to a treatment atmosphere for an exposure time of at least 1 second, wherein the treatment atmosphere has a relative humidity of 50% or more and a temperature of 50-100° C., and wherein the exposure time has a duration of 30 minutes or less, and cooling and optionally drying said seed.

Abstract: The present invention relates to formulations of ingenol mebutate and methods of preparation and use thereof. More specifically, the invention relates to formulations of ingenol-3-mebutate applied to the skin with occlusion, and methods for treating or preventing diseases or conditions.

Abstract: A connection pin for mounting in a through-hole of a component carrier, comprising an anchoring part adapted for insertion into said through-hole with a non press fit, a contact part adapted to extend outside said through-hole, and a flange part adapted to abut against said component carrier and located between said anchoring part and said contact part. The anchoring part is provided an internal cavity and the anchoring part comprises a wall surrounding the internal cavity, which wall has at least two wall portions forming deformation zones and adapted to be located in the through-hole when the anchoring part is inserted in the through-hole, such that, upon exertion of a force on a free end of the anchoring part of the pin when the anchoring part is inserted in the through-hole, the deformation zones are deformed within the through-hole to press fit the connection pin in the through-hole.

Abstract: Substantially anhydrous topical gel compositions comprising ingenol-3-angelate as a suspension in non-aqueous carriers.

Abstract: Aqueous topical liposome gel compositions comprising ingenol-3-angelate.

Abstract: Novel aqueous topical gel compositions comprising ingenol-3-angelate.

Abstract: The invention provides a topical composition for cutaneous application which is an oil-in-water emulsion comprising (a) an oily phase, (b) an ingenol derivative in dissolved form; (c) an aqueous phase buffered to a p H of below 4.5, (d) at least one surfactant.

Abstract: A method for mounting connection pins in respective through-holes. Each pin having an anchoring part for insertion into said through-hole, a contact part to extend outside said through-hole and having a contact end for contact with the surface of another module of the electronic assembly, and a flange part to abut against said component carrier and located between said anchoring part and said contact part. A die tool has several similar recesses all adapted to receive a contact end of the contact part of a connection pin. The anchoring part of the pin is inserted in a through-hole of the component carrier, and the pin is anchored in the component carrier by exerting a force on a free end of the anchoring part of the pin while an end surface of the contact end abuts the bottom surface of similar recesses in the die tool.

Abstract: Substantially anhydrous topical gel compositions comprising ingenol-3-angelate as a suspension in non-aqueous carriers.

Abstract: Aqueous topical liposome gel compositions comprising ingenol-3-angelate.

Abstract: Topical gel composition comprising ingenol-3-angelate and a silicone.

Abstract: Novel aqueous topical gel compositions comprising ingenol-3-angelate.

Abstract: A connection pin for mounting in a through-hole provided in a component carrier of an electronic assembly, the connection pin comprising an anchoring part adapted for insertion into said through-hole, a contact part adapted to extend outside said through-hole, and a flange part adapted to abut against said component carrier and located between said anchoring part and said contact part. The connection pin is provided with an internal cavity, which is provided with an outer opening at a free end of the anchoring part. The contact part is provided with a protruding elongated interconnection member at a free end thereof, and the respective shapes of the interconnection member and the internal cavity are such that the interconnection member is adapted for insertion into a corresponding internal cavity of another similar connection pin. A method for producing an electronic assembly with stackable modules is also disclosed.

Abstract: A substantially anhydrous pharmaceutical gel composition for cutaneous application comprising an ingenol derivative in dissolved or solubilized form, a solvent mixture of (a) a hydrophilic non-ionic surfactant; (b) a lipophilic non-ionic co-surfactant; (c) an oil; the composition further comprising an acidic compound, a co-solvent, a viscosity-increasing agent and a pharmaceutically acceptable, substantially anhydrous, non-solvent lipid carrier.

Abstract: The present invention relates to a topical gel composition comprising ingenol-3-angelate, wherein the composition provides greater flux, according to the in vitro diffusion test, of ingenol-3-angelate into the stratum corneum, epidermis and dermis after application of the gel composition to skin than does a reference gel of ingenol-3-angelate, namely the PICATO® product.

Abstract: Substantially anhydrous topical gel compositions comprising a homogeneous mixture of: (a) ingenol-3-angelate in dissolved form; and (b) anon-aqueous carrier.

Abstract: A substantially anhydrous topical composition comprises a homogenous mixture of (a) a therapeutically effective amount of an ingenol derivative in dissolved form; (b) an oily solvent for the ingenol derivative, (c) an acidic compound, and (d) optionally a pharmaceutically acceptable non-solvent lipid carrier.

Abstract: A topical composition for cutaneous application which is a water-in-oil emulsion comprises an oily phase comprising (a) an ingenol derivative in dissolved form; (b) at least one non-ionic surfactant selected from the group consisting of polyoxyl glycerides, polyoxyethylene castor oil derivatives, polyoxyethylene alkyl ethers, polysorbates, or a mixture of acrylamide acryloyldimethyl taurate copolymer, isohexadecane and polysorbate 80, sterols, fatty alcohols, fatty acid phosphonates, mono- or diglycol esters, mono- di- or polyglyceryl esters, mono-, di- or plyglucose esters, sucrose esters or sorbitan esters, the non-ionic surfactant being present in an amount of from about 0.5% by weight to about 10% by weight of the composition; (c) a solvent for the ingenol derivative; and an aqueous phase buffered to a pH of 2.6-3.7.

Abstract: Topical gel compositions comprising ingenol-3-angelate, wherein less than 10% of the ingenol-3-angelate degrades when the gel is stored for 2 years at 25° C.