Patents by Inventor Olaf Zoellner

Olaf Zoellner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240102996
    Abstract: Aspects of the present disclosure include systems for use in preparing a labelled biomolecule reagent. Systems according to certain embodiments include an input manager for receiving a request for a labelled biomolecule reagent, a memory for storing a dataset having a plurality of labelled biomolecule reagent storage identifiers, a processing module communicatively coupled to the memory and configured to identify one or more labelled biomolecule reagent storage identifiers from the dataset that corresponds to the labelled biomolecule reagent request and an output manager for providing the one or more identified labelled biomolecule reagent storage identifiers. A reagent preparatory apparatus for preparing the labelled biomolecule reagent from an activated biomolecule and activated label is also described. Methods for communicating and receiving a labelled biomolecule reagent request and preparing the subject labelled biomolecule reagents are also provided.
    Type: Application
    Filed: November 21, 2023
    Publication date: March 28, 2024
    Inventors: Olaf Zoellner, Eric Jensen, John Archdeacon, Brent S. Gaylord
  • Publication number: 20240069019
    Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.
    Type: Application
    Filed: September 1, 2023
    Publication date: February 29, 2024
    Inventors: Christina Fan, Olaf Zoellner
  • Publication number: 20240019434
    Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.
    Type: Application
    Filed: August 29, 2022
    Publication date: January 18, 2024
    Inventors: Christina Fan, Olaf Zoellner
  • Patent number: 11860159
    Abstract: Aspects of the present disclosure include systems for use in preparing a labelled biomolecule reagent. Systems according to certain embodiments include an input manager for receiving a request for a labelled biomolecule reagent, a memory for storing a dataset having a plurality of labelled biomolecule reagent storage identifiers, a processing module communicatively coupled to the memory and configured to identify one or more labelled biomolecule reagent storage identifiers from the dataset that corresponds to the labelled biomolecule reagent request and an output manager for providing the one or more identified labelled biomolecule reagent storage identifiers. A reagent preparatory apparatus for preparing the labelled biomolecule reagent from an activated biomolecule and activated label is also described. Methods for communicating and receiving a labelled biomolecule reagent request and preparing the subject labelled biomolecule reagents are also provided.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: January 2, 2024
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Olaf Zoellner, Eric Jensen, John Archdeacon, Brent S. Gaylord
  • Patent number: 11782059
    Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: October 10, 2023
    Assignee: Becton, Dickinson and Company
    Inventors: Christina Fan, Olaf Zoellner
  • Publication number: 20230125113
    Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.
    Type: Application
    Filed: August 22, 2022
    Publication date: April 27, 2023
    Inventors: Christina Fan, Christina Chang, Eleen Shum, Olaf Zoellner, Nidhanjali Bansal, James Ghadiali, Gretchen Yinbon Lam, Eric Jensen, Jurg Rohrer, Brent Gaylord, Jody Martin, Jason G. Vidal
  • Publication number: 20220324150
    Abstract: The invention relates to a method for improving an injection molding process, wherein a product is produced by an injection molding apparatus through an injection molding process from a precursor charge of precursor material based on process settings applied to the injection molding apparatus, wherein the injection molding process comprises injecting the precursor charge into a mold of the injection molding apparatus, wherein the precursor charge is produced through a precursor production process described by precursor production parameters, wherein the applied process settings are determined prior to the injection molding process by a computer simulation of the injection molding process executed by a computing apparatus, which computer simulation is based on a simulation model, on the precursor production parameters and on given process conditions of the injection molding process, which given process conditions comprise a shape of the mold. The invention also relates to a corresponding system.
    Type: Application
    Filed: November 18, 2020
    Publication date: October 13, 2022
    Inventors: Olaf Zoellner, Sebastian Zoppe, Christoph Bontenackels, Sairam Potaraju
  • Patent number: 11467157
    Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.
    Type: Grant
    Filed: February 12, 2020
    Date of Patent: October 11, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Christina Fan, Olaf Zoellner
  • Patent number: 11460468
    Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: October 4, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Christina Fan, Christina Chang, Eleen Shum, Olaf Zoellner, Nidhanjali Bansal, James Ghadiali, Gretchen Yinbon Lam, Eric Jensen, Jurg Rohrer, Brent Gaylord, Jody Martin, Jason G. Vidal
  • Publication number: 20220050097
    Abstract: Aspects of the present disclosure include systems for use in preparing a labelled biomolecule reagent. Systems according to certain embodiments include an input manager for receiving a request for a labelled biomolecule reagent, a memory for storing a dataset having a plurality of labelled biomolecule reagent storage identifiers, a processing module communicatively coupled to the memory and configured to identify one or more labelled biomolecule reagent storage identifiers from the dataset that corresponds to the labelled biomolecule reagent request and an output manager for providing the one or more identified labelled biomolecule reagent storage identifiers. A reagent preparatory apparatus for preparing the labelled biomolecule reagent from an activated biomolecule and activated label is also described. Methods for communicating and receiving a labelled biomolecule reagent request and preparing the subject labelled biomolecule reagents are also provided.
    Type: Application
    Filed: October 26, 2021
    Publication date: February 17, 2022
    Inventors: Olaf Zoellner, Eric Jensen, John Archdeacon, Brent S. Gaylord
  • Publication number: 20220001586
    Abstract: The invention relates to a method and system wherein an analysis system (6) measures derivative process parameters (7) from the derivative physical production process, wherein the precursor charge (3) is produced at a precursor production facility (8) at least 50 km distant from the physical production facility (2) through a precursor production process based on applied precursor production settings (9), wherein the precursor charge (3) is transported to the physical production facility (2), wherein the analysis system (6) measures precursor process parameters (11) from the precursor production process and precursor product parameters (12) from the precursor charge (3), wherein the analysis system (6) enters the applied derivative process settings (4), the measured derivative process parameters (7), the applied precursor production settings (9), the measured precursor process parameters (11), the measured precursor product parameters (12) as input to a process model (13), which process model (13) describes a
    Type: Application
    Filed: November 14, 2019
    Publication date: January 6, 2022
    Inventors: Olaf ZÖLLNER, Sebastian ZOPPE, Sairam POTARAJU, Rainer PROTTE, Christoph BONTENACKELS
  • Patent number: 11187699
    Abstract: Aspects of the present disclosure include systems for use in preparing a labelled biomolecule reagent. Systems according to certain embodiments include an input manager for receiving a request for a labelled biomolecule reagent, a memory for storing a dataset having a plurality of labelled biomolecule reagent storage identifiers, a processing module communicatively coupled to the memory and configured to identify one or more labelled biomolecule reagent storage identifiers from the dataset that corresponds to the labelled biomolecule reagent request and an output manager for providing the one or more identified labelled biomolecule reagent storage identifiers. A reagent preparatory apparatus for preparing the labelled biomolecule reagent from an activated biomolecule and activated label is also described. Methods for communicating and receiving a labelled biomolecule reagent request and preparing the subject labelled biomolecule reagents are also provided.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: November 30, 2021
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Olaf Zoellner, Eric Jensen, John Archdeacon, Brent S. Gaylord
  • Publication number: 20200215731
    Abstract: Process for producing a molded article, comprising a long fiber thermoplastic composite sheet (1) and a short fiber filled thermoplastic (2,3) component, preferably injected over the surface of the composite sheet, that are thermoformed.
    Type: Application
    Filed: December 19, 2017
    Publication date: July 9, 2020
    Inventors: Yilan LI, Eric QI, Jack CHANG, Sean GAO, Olaf ZÖLLNER, Thomas GRIMM
  • Publication number: 20200173992
    Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.
    Type: Application
    Filed: February 12, 2020
    Publication date: June 4, 2020
    Inventors: Christina Fan, Olaf Zoellner
  • Publication number: 20200124601
    Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.
    Type: Application
    Filed: July 1, 2019
    Publication date: April 23, 2020
    Inventors: Christina Fan, Olaf Zoellner
  • Patent number: 10338066
    Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: July 2, 2019
    Assignee: Cellular Research, Inc.
    Inventors: Christina Fan, Olaf Zoellner
  • Publication number: 20180267036
    Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.
    Type: Application
    Filed: May 30, 2018
    Publication date: September 20, 2018
    Inventors: Christina Fan, Olaf Zoellner
  • Publication number: 20180231530
    Abstract: Aspects of the present disclosure include systems for use in preparing a labelled biomolecule reagent. Systems according to certain embodiments include an input manager for receiving a request for a labelled biomolecule reagent, a memory for storing a dataset having a plurality of labelled biomolecule reagent storage identifiers, a processing module communicatively coupled to the memory and configured to identify one or more labelled biomolecule reagent storage identifiers from the dataset that corresponds to the labelled biomolecule reagent request and an output manager for providing the one or more identified labelled biomolecule reagent storage identifiers. A reagent preparatory apparatus for preparing the labelled biomolecule reagent from an activated biomolecule and activated label is also described. Methods for communicating and receiving a labelled biomolecule reagent request and preparing the subject labelled biomolecule reagents are also provided.
    Type: Application
    Filed: September 2, 2016
    Publication date: August 16, 2018
    Inventors: Olaf Zoellner, Eric Jensen, John Archdeacon, Brent S. Gaylord
  • Publication number: 20180088112
    Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.
    Type: Application
    Filed: September 25, 2017
    Publication date: March 29, 2018
    Inventors: Christina Fan, Christina Chang, Eleen Shum, Olaf Zoellner, Nidhanjali Bansal, James Ghadiali, Gretchen Yinbon Lam, Eric Jensen, Jurg Rohrer, Brent Gaylord, Jody Martin, Jason G. Vidal
  • Patent number: 8983878
    Abstract: A computer-implemented method for optimising an injection moulding process for producing thick-walled components based on a model parameterised on the basis of parameters to be predetermined is provided, wherein a component to be produced is represented in the model with a component geometry, and the method comprises at least the following steps: e) defining a group of parameters as primary characteristics on the basis of a relative influence of the parameters on a predetermined model response, and f) defining parameter values for the primary characteristics as starting values for a subsequent optimisation of the model and of respective tolerance ranges for the primary characteristics, c) optimising the parameter values of the individual primary characteristics with respect to a desired value of the model response in the respective tolerance ranges, proceeding from the starting values from step a), and d) setting the optimised parameter values from step c) as the corresponding starting parameter values on an
    Type: Grant
    Filed: October 12, 2010
    Date of Patent: March 17, 2015
    Assignee: Bayer MaterialScience AG
    Inventors: Florian Dorin, Christoph Klinkenberg, Olaf Zoellner