Patents by Inventor Olaf Zoellner
Olaf Zoellner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240102996Abstract: Aspects of the present disclosure include systems for use in preparing a labelled biomolecule reagent. Systems according to certain embodiments include an input manager for receiving a request for a labelled biomolecule reagent, a memory for storing a dataset having a plurality of labelled biomolecule reagent storage identifiers, a processing module communicatively coupled to the memory and configured to identify one or more labelled biomolecule reagent storage identifiers from the dataset that corresponds to the labelled biomolecule reagent request and an output manager for providing the one or more identified labelled biomolecule reagent storage identifiers. A reagent preparatory apparatus for preparing the labelled biomolecule reagent from an activated biomolecule and activated label is also described. Methods for communicating and receiving a labelled biomolecule reagent request and preparing the subject labelled biomolecule reagents are also provided.Type: ApplicationFiled: November 21, 2023Publication date: March 28, 2024Inventors: Olaf Zoellner, Eric Jensen, John Archdeacon, Brent S. Gaylord
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Publication number: 20240069019Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.Type: ApplicationFiled: September 1, 2023Publication date: February 29, 2024Inventors: Christina Fan, Olaf Zoellner
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Publication number: 20240019434Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.Type: ApplicationFiled: August 29, 2022Publication date: January 18, 2024Inventors: Christina Fan, Olaf Zoellner
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Patent number: 11860159Abstract: Aspects of the present disclosure include systems for use in preparing a labelled biomolecule reagent. Systems according to certain embodiments include an input manager for receiving a request for a labelled biomolecule reagent, a memory for storing a dataset having a plurality of labelled biomolecule reagent storage identifiers, a processing module communicatively coupled to the memory and configured to identify one or more labelled biomolecule reagent storage identifiers from the dataset that corresponds to the labelled biomolecule reagent request and an output manager for providing the one or more identified labelled biomolecule reagent storage identifiers. A reagent preparatory apparatus for preparing the labelled biomolecule reagent from an activated biomolecule and activated label is also described. Methods for communicating and receiving a labelled biomolecule reagent request and preparing the subject labelled biomolecule reagents are also provided.Type: GrantFiled: October 26, 2021Date of Patent: January 2, 2024Assignee: BECTON, DICKINSON AND COMPANYInventors: Olaf Zoellner, Eric Jensen, John Archdeacon, Brent S. Gaylord
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Patent number: 11782059Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.Type: GrantFiled: July 1, 2019Date of Patent: October 10, 2023Assignee: Becton, Dickinson and CompanyInventors: Christina Fan, Olaf Zoellner
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Publication number: 20230125113Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.Type: ApplicationFiled: August 22, 2022Publication date: April 27, 2023Inventors: Christina Fan, Christina Chang, Eleen Shum, Olaf Zoellner, Nidhanjali Bansal, James Ghadiali, Gretchen Yinbon Lam, Eric Jensen, Jurg Rohrer, Brent Gaylord, Jody Martin, Jason G. Vidal
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Publication number: 20220324150Abstract: The invention relates to a method for improving an injection molding process, wherein a product is produced by an injection molding apparatus through an injection molding process from a precursor charge of precursor material based on process settings applied to the injection molding apparatus, wherein the injection molding process comprises injecting the precursor charge into a mold of the injection molding apparatus, wherein the precursor charge is produced through a precursor production process described by precursor production parameters, wherein the applied process settings are determined prior to the injection molding process by a computer simulation of the injection molding process executed by a computing apparatus, which computer simulation is based on a simulation model, on the precursor production parameters and on given process conditions of the injection molding process, which given process conditions comprise a shape of the mold. The invention also relates to a corresponding system.Type: ApplicationFiled: November 18, 2020Publication date: October 13, 2022Inventors: Olaf Zoellner, Sebastian Zoppe, Christoph Bontenackels, Sairam Potaraju
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Patent number: 11467157Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.Type: GrantFiled: February 12, 2020Date of Patent: October 11, 2022Assignee: Becton, Dickinson and CompanyInventors: Christina Fan, Olaf Zoellner
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Patent number: 11460468Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.Type: GrantFiled: September 25, 2017Date of Patent: October 4, 2022Assignee: Becton, Dickinson and CompanyInventors: Christina Fan, Christina Chang, Eleen Shum, Olaf Zoellner, Nidhanjali Bansal, James Ghadiali, Gretchen Yinbon Lam, Eric Jensen, Jurg Rohrer, Brent Gaylord, Jody Martin, Jason G. Vidal
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Publication number: 20220050097Abstract: Aspects of the present disclosure include systems for use in preparing a labelled biomolecule reagent. Systems according to certain embodiments include an input manager for receiving a request for a labelled biomolecule reagent, a memory for storing a dataset having a plurality of labelled biomolecule reagent storage identifiers, a processing module communicatively coupled to the memory and configured to identify one or more labelled biomolecule reagent storage identifiers from the dataset that corresponds to the labelled biomolecule reagent request and an output manager for providing the one or more identified labelled biomolecule reagent storage identifiers. A reagent preparatory apparatus for preparing the labelled biomolecule reagent from an activated biomolecule and activated label is also described. Methods for communicating and receiving a labelled biomolecule reagent request and preparing the subject labelled biomolecule reagents are also provided.Type: ApplicationFiled: October 26, 2021Publication date: February 17, 2022Inventors: Olaf Zoellner, Eric Jensen, John Archdeacon, Brent S. Gaylord
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Publication number: 20220001586Abstract: The invention relates to a method and system wherein an analysis system (6) measures derivative process parameters (7) from the derivative physical production process, wherein the precursor charge (3) is produced at a precursor production facility (8) at least 50 km distant from the physical production facility (2) through a precursor production process based on applied precursor production settings (9), wherein the precursor charge (3) is transported to the physical production facility (2), wherein the analysis system (6) measures precursor process parameters (11) from the precursor production process and precursor product parameters (12) from the precursor charge (3), wherein the analysis system (6) enters the applied derivative process settings (4), the measured derivative process parameters (7), the applied precursor production settings (9), the measured precursor process parameters (11), the measured precursor product parameters (12) as input to a process model (13), which process model (13) describes aType: ApplicationFiled: November 14, 2019Publication date: January 6, 2022Inventors: Olaf ZÖLLNER, Sebastian ZOPPE, Sairam POTARAJU, Rainer PROTTE, Christoph BONTENACKELS
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Patent number: 11187699Abstract: Aspects of the present disclosure include systems for use in preparing a labelled biomolecule reagent. Systems according to certain embodiments include an input manager for receiving a request for a labelled biomolecule reagent, a memory for storing a dataset having a plurality of labelled biomolecule reagent storage identifiers, a processing module communicatively coupled to the memory and configured to identify one or more labelled biomolecule reagent storage identifiers from the dataset that corresponds to the labelled biomolecule reagent request and an output manager for providing the one or more identified labelled biomolecule reagent storage identifiers. A reagent preparatory apparatus for preparing the labelled biomolecule reagent from an activated biomolecule and activated label is also described. Methods for communicating and receiving a labelled biomolecule reagent request and preparing the subject labelled biomolecule reagents are also provided.Type: GrantFiled: September 2, 2016Date of Patent: November 30, 2021Assignee: BECTON, DICKINSON AND COMPANYInventors: Olaf Zoellner, Eric Jensen, John Archdeacon, Brent S. Gaylord
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Publication number: 20200215731Abstract: Process for producing a molded article, comprising a long fiber thermoplastic composite sheet (1) and a short fiber filled thermoplastic (2,3) component, preferably injected over the surface of the composite sheet, that are thermoformed.Type: ApplicationFiled: December 19, 2017Publication date: July 9, 2020Inventors: Yilan LI, Eric QI, Jack CHANG, Sean GAO, Olaf ZÖLLNER, Thomas GRIMM
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Publication number: 20200173992Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.Type: ApplicationFiled: February 12, 2020Publication date: June 4, 2020Inventors: Christina Fan, Olaf Zoellner
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Publication number: 20200124601Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.Type: ApplicationFiled: July 1, 2019Publication date: April 23, 2020Inventors: Christina Fan, Olaf Zoellner
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Patent number: 10338066Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.Type: GrantFiled: May 30, 2018Date of Patent: July 2, 2019Assignee: Cellular Research, Inc.Inventors: Christina Fan, Olaf Zoellner
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Publication number: 20180267036Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.Type: ApplicationFiled: May 30, 2018Publication date: September 20, 2018Inventors: Christina Fan, Olaf Zoellner
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Publication number: 20180231530Abstract: Aspects of the present disclosure include systems for use in preparing a labelled biomolecule reagent. Systems according to certain embodiments include an input manager for receiving a request for a labelled biomolecule reagent, a memory for storing a dataset having a plurality of labelled biomolecule reagent storage identifiers, a processing module communicatively coupled to the memory and configured to identify one or more labelled biomolecule reagent storage identifiers from the dataset that corresponds to the labelled biomolecule reagent request and an output manager for providing the one or more identified labelled biomolecule reagent storage identifiers. A reagent preparatory apparatus for preparing the labelled biomolecule reagent from an activated biomolecule and activated label is also described. Methods for communicating and receiving a labelled biomolecule reagent request and preparing the subject labelled biomolecule reagents are also provided.Type: ApplicationFiled: September 2, 2016Publication date: August 16, 2018Inventors: Olaf Zoellner, Eric Jensen, John Archdeacon, Brent S. Gaylord
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Publication number: 20180088112Abstract: Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.Type: ApplicationFiled: September 25, 2017Publication date: March 29, 2018Inventors: Christina Fan, Christina Chang, Eleen Shum, Olaf Zoellner, Nidhanjali Bansal, James Ghadiali, Gretchen Yinbon Lam, Eric Jensen, Jurg Rohrer, Brent Gaylord, Jody Martin, Jason G. Vidal
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Patent number: 8983878Abstract: A computer-implemented method for optimising an injection moulding process for producing thick-walled components based on a model parameterised on the basis of parameters to be predetermined is provided, wherein a component to be produced is represented in the model with a component geometry, and the method comprises at least the following steps: e) defining a group of parameters as primary characteristics on the basis of a relative influence of the parameters on a predetermined model response, and f) defining parameter values for the primary characteristics as starting values for a subsequent optimisation of the model and of respective tolerance ranges for the primary characteristics, c) optimising the parameter values of the individual primary characteristics with respect to a desired value of the model response in the respective tolerance ranges, proceeding from the starting values from step a), and d) setting the optimised parameter values from step c) as the corresponding starting parameter values on anType: GrantFiled: October 12, 2010Date of Patent: March 17, 2015Assignee: Bayer MaterialScience AGInventors: Florian Dorin, Christoph Klinkenberg, Olaf Zoellner