Abstract: A method for assessing nerve fiber excitability is disclosed. The method comprises: arranging an electrode in contact with skin of a person; determining a first and a second threshold value based on a stimulation current pulse of a first and a second waveform, respectively; wherein said determining of the first threshold value and said determining of the second threshold value each comprises: repeatedly providing a stimulation current pulse of the first or second waveform, respectively, through the electrode, wherein a stimulation current strength is altered between repetitions; and receiving signals from an interaction element with which the person interacts, said signals from the interaction element providing an indication of the first threshold value or the second threshold value, respectively, corresponding to a stimulation current strength necessary to be perceived by the person; and determining at least one measure of psychophysical perception based on the determined first and second threshold values.

Abstract: A method for assessing nerve fiber excitability is disclosed. The method comprises: arranging an electrode in contact with skin of a person; determining a first and a second threshold value based on a stimulation current pulse of a first and a second waveform, respectively; wherein said determining of the first threshold value and said determining of the second threshold value each comprises: repeatedly providing a stimulation current pulse of the first or second waveform, respectively, through the electrode, wherein a stimulation current strength is altered between repetitions; and receiving signals from an interaction element with which the person interacts, said signals from the interaction element providing an indication of the first threshold value or the second threshold value, respectively, corresponding to a stimulation current strength necessary to be perceived by the person; and determining at least one measure of psychophysical perception based on the determined first and second threshold values.

Abstract: According to an aspect of the present inventive concept there is provided a method for determining a nociceptive withdrawal reflex threshold of a person, the method comprising: applying a plurality of stimulations to a person with different stimulation intensity levels in accordance with a stimulation intensity algorithm, wherein the plurality of stimulations comprises at least one stimulation having an intensity level provoking a spinal cord withdrawal reflex in the person, recording electromyographic data representative of muscle activity of the person in response to each stimulation of the plurality of stimulations, and processing the stimulation intensity levels and the electromyographic data according to a threshold calculation algorithm to calculate a measure of the nociceptive withdrawal reflex threshold of the person. There is also provided a corresponding system.

Abstract: A product, e.g. an insole for a shoe, fitting onto a person's foot sole based on a platform (SM) of a flexible and electrically isolating material. Multiple stimulation electrodes (S1, S2, S3) with adhesive stimulation areas of at least 1 cm2 are spatially distributed on the platform (SM). A conducting and adhesive ground plane electrode (G) with at least an area of 10 times a stimulation electrode area is arranged for contacting the person's foot. An electric interface (I) comprising a plug or socket with externally accessible electrical connectors to allow external individual electrical access to the plurality of stimulation electrode areas (S1, S2, S3) and to the ground plane electrode (G). The electric interface is capable of handling at least a voltage of 200 V, preferably 400 V. Such product is suited for reflex-based gait therapy, where the person's withdrawal reflex is triggered by a painful stimulation of the person's foot sole.

Abstract: A device and method for gait training, such as for rehabilitation of a person after a stroke is provided. In some embodiments, the device comprises a stimulator, preferably electric stimulator, for provoking a spinal cord withdrawal reflex in the person by stimulation on the person's foot in response to a control signal. Hereby, the person's leg will move and initiate a gait swing. A sensor is placed to sense movement of the leg and provide a feedback signal accordingly. A processor unit with a processor runs a control algorithm which calculates the control signal in response to the feedback signal. Thus, the method is based on a closed-loop design, and the control signal is preferably calculated for each walking step, and it is preferably based on the feedback signal obtained from the preceding walking step. Hereby reflex habituation can be accounted for.

Abstract: Aspects of the invention relate to a device for predicting cutaneous afferent nerve fiber excitation from an electrical potential applied to a cutaneous tissue by an electrode and methods of using the same. In some embodiments, such devices and methods concern the electrical stimulation of nerves in the skin so as to ameliorate pain in a subject. Accordingly, methods making and using cutaneous electrodes are provided.

Abstract: A device and method for gait training, such as for rehabilitation of a person after a stroke is provided. In some embodiments, the device comprises a stimulator, preferably electric stimulator, for provoking a spinal cord withdrawal reflex in the person by stimulation on the person's foot in response to a control signal. Hereby, the person's leg will move and initiate a gait swing. A sensor is placed to sense movement of the leg and provide a feedback signal accordingly. A processor unit with a processor runs a control algorithm which calculates the control signal in response to the feedback signal. Thus, the method is based on a closed-loop design, and the control signal is preferably calculated for each walking step, and it is preferably based on the feedback signal obtained from the preceding walking step. Hereby reflex habituation can be accounted for.