Patents by Inventor Oleg Fedorkin

Oleg Fedorkin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9765349
    Abstract: The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: September 19, 2017
    Assignee: iBio, Inc.
    Inventors: Oleg Fedorkin, Shailaja Rabindran, Vidadi Yusibov
  • Publication number: 20170121721
    Abstract: The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
    Type: Application
    Filed: January 4, 2017
    Publication date: May 4, 2017
    Inventors: Oleg Fedorkin, Shailaja Rabindran, Vidadi Yusibov
  • Patent number: 9551001
    Abstract: The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: January 24, 2017
    Assignee: iBio, Inc.
    Inventors: Oleg Fedorkin, Shailaja Rabindran, Vidadi Yusibov
  • Publication number: 20160060644
    Abstract: The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
    Type: Application
    Filed: January 22, 2015
    Publication date: March 3, 2016
    Inventors: Oleg Fedorkin, Shailaja Rabindran, Vidadi Yusibov
  • Patent number: 8951791
    Abstract: The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: February 10, 2015
    Assignee: iBio, Inc.
    Inventors: Oleg Fedorkin, Shailaja Rabindran, Vidadi Yusibov
  • Publication number: 20140220674
    Abstract: The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
    Type: Application
    Filed: December 2, 2013
    Publication date: August 7, 2014
    Applicant: iBio, Inc.
    Inventors: Oleg Fedorkin, Shailaja Rabindran, Vidadi Yusibov
  • Patent number: 8597942
    Abstract: The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: December 3, 2013
    Assignee: iBio, Inc.
    Inventors: Oleg Fedorkin, Shailaja Rabindran, Vidadi Yusibov
  • Publication number: 20120096585
    Abstract: The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
    Type: Application
    Filed: September 23, 2011
    Publication date: April 19, 2012
    Inventors: Oleg Fedorkin, Shailaja Rabindran, Vidadi Yusibov
  • Patent number: 8058511
    Abstract: The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: November 15, 2011
    Assignee: Fraunhofer USA, Inc.
    Inventors: Oleg Fedorkin, Shailaja Rabindran, Vidadi Yusibov
  • Patent number: 7491509
    Abstract: The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
    Type: Grant
    Filed: February 3, 2004
    Date of Patent: February 17, 2009
    Assignee: Fraunhofer USA, Inc.
    Inventors: Oleg Fedorkin, Shailaja Rabindran, Vidadi Yusibov
  • Publication number: 20080241931
    Abstract: The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
    Type: Application
    Filed: February 21, 2008
    Publication date: October 2, 2008
    Inventors: Oleg Fedorkin, Shailaja Rabindran, Vidadi Yusibov
  • Publication number: 20070178148
    Abstract: The present invention relates to compositions and systems for expressing pharmaceutically active gene products in plants. In particular, the invention provides compositions, systems and methods for the production of human growth hormone in plants. Provided are nucleic acid and protein sequences, expression and vector constructs, host cells and plants capable of expressing human growth hormone, and compositions and kits comprising produced human growth hormone. Additionally provided are methods for production and use of the compositions of the invention.
    Type: Application
    Filed: February 5, 2006
    Publication date: August 2, 2007
    Inventors: Vidadi Yusibov, Shailaja Rabindran, Marina Skarjinskaia, Oleg Fedorkin, Burt Ensley
  • Publication number: 20050026291
    Abstract: The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
    Type: Application
    Filed: February 3, 2004
    Publication date: February 3, 2005
    Inventors: Oleg Fedorkin, Shailaja Rabindran, Vidadi Yusibov