Patents by Inventor Oleg Nikolaevich Chupakhin

Oleg Nikolaevich Chupakhin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9790227
    Abstract: The claimed invention relates to the field of biologically active compounds and concerns 2-methylsulphanyl-6-nitro-7-oxo-1,2,4-triazolo[5,1-c][1,2,4]triazinide L-arginine dihydrate, which exhibits an antiviral effect and is intended for the treatment and prophylaxis of human and animal viral diseases, primarily West Nile Virus, and can be used in the chemical and pharmaceutical industry, in scientific research laboratories and medical facilities, and also in veterinary science. The claimed invention is directed toward achieving the technical result of creating a novel effective drug of the azoloazine variety which exhibits antiviral activity toward a group of RNA-containing viruses, and reducing the dependence of the active compound on cell metabolism. This technical result is achieved in the creation of the novel drug 2-methylsulphanyl-6-nitro-7-oxo-1,2,4-triazolo[5,1-c][1,2,4]triazinide L-arginine dihydrate, which exhibits an aniviral effect and has the formula (I).
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: October 17, 2017
    Assignee: LIMITED LIABILITY COMPANY “URAL CENTER OF BIOPHARMACEUTICAL TECHNOLOGY”
    Inventors: Oleg Nikolaevich Chupakhin, Vladimir Leonidovich Rusinov, Evgeny Narcissovich Ulomsky, Konstantin Valerievich Savateev, Stepan Sergeevich Borisov, Natalia Alexandrovna Novikova, Svetlana Yakovlevna Loginova, Sergey Vladimirovich Borisevich, Pavel Vladimirovich Sorokin
  • Publication number: 20160318934
    Abstract: The claimed invention relates to the field of biologically active compounds and concerns 2-methylsulphanyl-6-nitro-7-oxo-1,2,4-triazolo[5,1-c][1,2,4]triazinide L-arginine dihydrate, which exhibits an antiviral effect and is intended for the treatment and prophylaxis of human and animal viral diseases, primarily West Nile Virus, and can be used in the chemical and pharmaceutical industry, in scientific research laboratories and medical facilities, and also in veterinary science. The claimed invention is directed toward achieving the technical result of creating a novel effective drug of the azoloazine variety which exhibits antiviral activity toward a group of RNA-containing viruses, and reducing the dependence of the active compound on cell metabolism. This technical result is achieved in the creation of the novel drug 2-methylsulphanyl-6-nitro-7-oxo-1,2,4-triazolo[5,1-c][1,2,4]triazinide L-arginine dihydrate, which exhibits an aniviral effect and has the formula (I).
    Type: Application
    Filed: October 21, 2014
    Publication date: November 3, 2016
    Inventors: Oleg Nikolaevich CHUPAKHIN, Vladimir Leonidovich RUSINOV, Evgeny Narcissovich ULOMSKY, Konstantin Valerievich SAVATEEV, Stepan Sergeevich BORISOV, Natalia Alexandrovna NOVIKOVA, Svetlana Yakovlevna LOGINOVA, Sergey Vladimirovich BORISEVICH, Pavel Vladimirovich SOROKIN
  • Patent number: 6313111
    Abstract: Substitued 6H-1,3,4-thiadiazin-2-amines of the following general formula: wherein Ar is phenyl optionally substituted with one or more chloro, bromo atoms, C1-C4 alkoxy, or C1-C4 alkyl groups; and represents a morpholino, thimomorpholino, piperidino, pyrrolidino, or hexamethylenimino moieties, the pharmaceutically acceptable salts thereof and the use of them anasethetic, cardiovascular and hypometabolic agents and pharmaceutical compositions containing them.
    Type: Grant
    Filed: December 8, 1998
    Date of Patent: November 6, 2001
    Assignees: The Procter & Gamble Company, Nauchno-Tekhnologicheskoe Predpriyatie “Ligand” (Tovarischestvo S Ogranichennoi Otvetstvennostiju)
    Inventors: Oleg Nikolaevich Chupakhin, Larisa Petrovna Sidorova, Emma Afanasievna Tarakhty, Antonina Petrovna Novikova, Natalya Mikhailovna Perova, Valentin Antonovich Vinogradov, Michiel Franciscus van Ginkel
  • Patent number: 6117867
    Abstract: Substituted 6-R-1,3,4-thiadiazin-2-amines of the following general formula: ##STR1## wherein Ar is phenyl or phenyl optionally substituted with one or more chloro, bromo atoms, C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 alkyl groups; R.sup.1 and R.sup.2 are each independently hydrogen atom or C.sub.1 -C.sub.4 alkyl moiety; and R.sup.3 and R.sup.4 are independently selected from C.sub.1 -C.sub.4 alkyl groups and pharmaceutically acceptable salts thereof, the use of them as anaesthetics, cardiovascular and hypometabolic agents and pharmaceutical compositions containing them.
    Type: Grant
    Filed: August 18, 1998
    Date of Patent: September 12, 2000
    Assignees: Procter & Gamble Company, Nauchno-Tekhnologicheskoepredpriyatie "Ligand"(Tovarischestvo S Organichennol Otvetstvennostju)
    Inventors: Oleg Nikolaevich Chupakhin, Larisa Petrovna Sidorova, Emma Afanasievna Tarakhty, Antonina Petrovna Novikova, Natalya Mikhailovna Perova, Valentin Antonovich Vinogradov, Michiel Franciscus van Ginkel
  • Patent number: 6028068
    Abstract: Substituted 6H-1,3,4-thiadiazin-2-amines of the following general formula: ##STR1## wherein ##STR2## represents a morpholino, thiomorpholino, piperidino, pyrrolidino, or hexamethyienimino moiety, and pharmaceutically acceptable salts thereof which are used as anaesthetics, cardiovascular and hypometabolic agents, and the pharmaceutical compositions containing them.
    Type: Grant
    Filed: January 21, 1999
    Date of Patent: February 22, 2000
    Assignees: The Procter & Gamble Company, Nauchno-Tekhnologicheskoe Predpriyatie "Ligand"(Tovarischestvo S Ogranichennoi Otvetstvennostju)
    Inventors: Oleg Nikolaevich Chupakhin, Larisa Petrovna Sidorova, Emma Afanasievna Tarakhty, Antonina Petrovna Novikova, Natalya Mikhailovna Perova, Valentin Antonovich Vinogradov