Abstract: The invention relates to devices, a systems, and associated methods for use, delivery, and manufacture for changing the blood flow into an aneurysm designed to induce aneurysm thrombosis and/or the exclusion from blood flow and pressure of the aneurysm in order to prevent further growth and eventual rupture. In some embodiments, the various aspects of the invention are directed to treating a cerebral aneurysm.

Abstract: An apparatus, system and method for re-canalization or opening a passage through an occlusion in a blood vessel is disclosed. The apparatus and method, which are appropriate for both cardiovascular as well as peripheral vessels, use hydraulic pressure to drive a vibratable member, and the system includes a control unit to permit the frequency or amplitude of oscillation of the vibratable member to be adjusted to suit the morphology or hardness of the target occlusion. Also disclosed is a method for adjusting the force of vibration.

Abstract: The device and method of the invention generally relate to a system and method for percutaneous delivery, implantation and securement of an anchor at a target site. The system comprises an anchor having a bridge, a first stabilizer having a crimped state and a deployed state, a second stabilizer having a crimped state and a deployed state, and a positioning arm. The system may further comprise a cannula, pushrod, and sheath. The system permits the deposit of an anchor at a target location in the body by utilizing a controlled amount of force. The anchors and methods are particularly well-suited to implantation within the body of a living animal or human to monitor various physiological conditions.

Abstract: A method and system for generating stabilized intravascular ultrasonic images are provided. The system includes a probe instrument, having an ultrasonic signal transmitter and a reflected ultrasonic signal receiver, the reflected signals containing information about a tubular environment, and a processor and post-processor, capable of converting inputted signals into one or more, preferably a series of, images. The method for stabilizing images involves the processor and post-processor input and output. The post-processor determines the environment center at each reflection position, detects the tubular environment edges, and aligns the image center with the environment center thereby limiting image drift and stabilizing the images. The processor may also filter images to improve image stabilization and remove motion interference and/or extract the environment's 3D shape. The method and device are of particular use in a vascular lumen, where image drift may occur due to heart beat or blood flow.

Abstract: A method and system for generating stabilized intravascular ultrasonic images are provided. The system may include a probe instrument, such as a catheter, connected to a processor and a post-processor. The method of using the system to stabilize images and the method for stabilizing images involve the process by which the processor and post-processor stabilize the image. A computer readable medium containing executable instructions for controlling a computer containing the processor and post-processor to perform the method of stabilizing images is also provided. The probe instrument, which has a transmitter for transmitting ultrasonic signals and a receiver for receiving reflected ultrasonic signals that contain information about a tubular environment, such as a body lumen, preferably is a catheter.

Abstract: An apparatus, system and method for re-canalization or opening a passage through an occlusion in a blood vessel is disclosed. The apparatus and method, which are appropriate for both cardiovascular as well as peripheral vessels, use hydraulic pressure to drive a vibratable member, and the system includes a control unit to permit the frequency or amplitude of oscillation of the vibratable member to be adjusted to suit the morphology or hardness of the target occlusion. Also disclosed is a method for adjusting the force of vibration.