Abstract: Performing an enhanced oil recovery (EOR) injection operation in an oilfield having a reservoir may include obtaining a EOR scenarios that each include a chemical agent, obtaining a three-dimensional (3D) porous solid image of a core sample, and generating a 3D pore scale model from the 3D porous solid image. The core sample is a 3D porous medium representing a portion of the oilfield. The 3D pore scale model describes a physical pore structure in the 3D porous medium. Simulations are performed using the EOR scenarios to obtain simulation results by, for each EOR scenario, simulating, on the first 3D pore scale model, the EOR injection operation using the chemical agent specified by the EOR scenario to generate a simulation result. A comparative analysis of the simulation results is performed to obtain a selected chemical agent. Further, an operation is performed using the selected chemical agent.