Patents by Inventor Oleksandr GRYTSAI

Oleksandr GRYTSAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11440906
    Abstract: The present disclosure relates to biguanide derivatives of formula (I) and their rearrangement products. The present disclosure also relates to the use of these compounds in a method for treating cancer, in particular melanoma.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: September 13, 2022
    Assignees: Centre National de la Recherche Scientifique, INSERM (Institut National de la Santé et de la Recherche Médicale), Université Côte d'Azur
    Inventors: Rachid Benhida, Stephane Rocchi, Cyril Ronco, Emile Jaune, Oleksandr Grytsai, Nedra Tekaya
  • Publication number: 20210380547
    Abstract: The present invention relates to a compound or a pharmaceutically acceptable salt thereof of formulae (I) and (II), and a pharmaceutical composition comprising such compound for use for treating a cancer, particularly a cancer overexpressing CXCR1 and CXCR2 receptors, such as medulloblastoma, head and neck and kidney cancer. The invention further relates to such compounds for use for treating macular degeneration.
    Type: Application
    Filed: October 17, 2019
    Publication date: December 9, 2021
    Inventors: RACHID BENHIDA, GILLES PAGES, MAEVA DUFIES, LUC DEMANGE, CYRIL RONCO, OLEKSANDR GRYTSAI
  • Publication number: 20200308156
    Abstract: The present disclosure relates to biguanide derivatives of formula (I) and their rearrangement products. The present disclosure also relates to the use of these compounds in a method for treating cancer, in particular melanoma.
    Type: Application
    Filed: December 21, 2018
    Publication date: October 1, 2020
    Inventors: Rachid BENHIDA, Stephane ROCCHI, Cyril RONCO, Emile JAUNE, Oleksandr GRYTSAI, Nedra TEKAYA