Patents by Inventor Oleksandr Zabudkin

Oleksandr Zabudkin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LENALIDOMIDE IMMEDIATE RELEASE FORMULATIONS
    Publication number: 20200323838
    Abstract: The present invention provides for a pharmaceutical composition comprising lenalidomide form A, a filler and a disintegrant and a superdisintegrant. The present invention further relates to a process for the preparation of said composition. The composition according to the invention may be used as medicament, particularly for the treatment of multiple myeloma and myeolodisplastic syndromes.
    Type: Application
    Filed: October 26, 2018
    Publication date: October 15, 2020
    Inventors: Oleksandr Zabudkin, Vladimir Matha, Iaroslav Matviienko
  • Method for the synthesis of rapamycin derivatives
    Patent number: 10308665
    Abstract: The present invention relates to a method for the production of a rapamycin derivative of formula (I), the method comprising the preparation of a 2-(tri-substituted silyl)oxyethyl triflate by reacting ethylene oxide and a tri-substituted silyl triflate, reaction of the resulting 2-(tri-substituted silyl)oxyethyl triflate with rapamycin in the presence of a molar excess of organic base, and deprotection to obtain the rapamycin derivative of compound (I).
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: June 4, 2019
    Assignee: Synbias Pharma AG
    Inventors: Oleksandr Zabudkin, Christian Schickaneder, Iaroslav Matviienko, Volodymyr Sypchenko
  • VINORELBINE MONOTARTRATE AND ITS PHARMACEUTICAL USE
    Publication number: 20190092792
    Abstract: The present invention is directed to crystalline vinorelbine monotartrate and its use for the prevention and treatment of cancer, particularly non-small cell lung cancer or breast cancer. The present invention also relates to a corresponding method for the manufacture of crystalline vinorelbine monotartrate.
    Type: Application
    Filed: March 9, 2016
    Publication date: March 28, 2019
    Applicant: SYNBIAS PHARMA AG
    Inventors: Oleksandr Zabudkin, Viktor Matviyenko, Vladimir Matha, Christian Schickaneder, Iaroslav Matviienko, Volodymyr Sypchenko
  • METHOD FOR THE SYNTHESIS OF RAPAMYCIN DERIVATIVES
    Publication number: 20190010168
    Abstract: The present invention relates to a method for the production of a rapamycin derivative of formula (I), the method comprising the preparation of a 2-(tri-substituted silyl)oxyethyl triflate by reacting ethylene oxide and a tri-substituted silyl triflate, reaction of the resulting 2-(tri-substituted silyl)oxyethyl triflate with rapamycin in the presence of a molar excess of organic base, and deprotection to obtain the rapamycin derivative of compound (I).
    Type: Application
    Filed: June 22, 2016
    Publication date: January 10, 2019
    Inventors: Oleksandr Zabudkin, Christian Schickaneder, Iaroslav Matviienko, Volodymyr Sypchenko
  • METHOD FOR THE SYNTHESIS OF PENTOSTATIN
    Publication number: 20180201966
    Abstract: The present invention relates to a method for the stereo-selective production of pentostatin comprising an enzymatic transglycosylation reaction between 6,7-dihydroimidazo-[4,5-d]-[1,3]diazepin-8(3H)-one and a 2?-deoxyribonucleoside, followed by an ruthenium-catalyzed asymmetric transfer hydrogenation.
    Type: Application
    Filed: July 6, 2016
    Publication date: July 19, 2018
    Inventors: Oleksandr Zabudkin, Christian Schickaneder, Iaroslav Matviienko, Volodymyr Sypchenko