Patents by Inventor Oleksii Dubrovskyi

Oleksii Dubrovskyi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for measuring cell permeability
    Patent number: 9588106
    Abstract: Embodiments of the present invention provide an in vitro assay that measures cell monolayer permeability. The assay utilizes detection of a binding pair initially separated by the cell monolayer as a qualitative and quantitative measure of the permeability of the monolayer. In certain embodiments, the assay is performed in the presence of a test substance that may or may not affect cell permeability. In particular aspects, the assay is performed on a substrate that is elastic. One can also assay spatial resolution of local changes by visualizing regional variations of the cell monolayers.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: March 7, 2017
    Assignee: The University of Chicago
    Inventors: Oleksii Dubrovskyi, Konstantin Birukov
  • Methods and Compositions for Measuring Cell Permeability
    Publication number: 20140065638
    Abstract: Embodiments of the present invention provide an in vitro assay that measures cell monolayer permeability. The assay utilizes detection of a binding pair initially separated by the cell monolayer as a qualitative and quantitative measure of the permeability of the monolayer. In certain embodiments, the assay is performed in the presence of a test substance that may or may not affect cell permeability. In particular aspects, the assay is performed on a substrate that is elastic. One can also assay spatial resolution of local changes by visualizing regional variations of the cell monolayers.
    Type: Application
    Filed: September 5, 2013
    Publication date: March 6, 2014
    Applicant: The University of Chicago
    Inventors: Oleksii Dubrovskyi, Konstantin Birukov