Patents by Inventor Olga Fedorova

Olga Fedorova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA
    Publication number: 20240018169
    Abstract: The present invention provides compositions and methods for inhibiting group II intron splicing for treating or preventing a disease or disorder associated with an organism harboring an active group II intron. The present invention also provides compositions and methods for inhibiting group II intron splicing for inhibiting, preventing or reducing growth of an organism harboring an active group II intron.
    Type: Application
    Filed: August 28, 2023
    Publication date: January 18, 2024
    Inventors: Anna Marie Pyle, Olga Fedorova, Erik Jagdmann, Michael Van Zandt, Lin Yuan, Albert DeBerardinis
  • Compositions and methods for inhibiting group II intron RNA
    Patent number: 11739104
    Abstract: The present invention provides compositions and methods for inhibiting group II intron splicing for treating or preventing a disease or disorder associated with an organism harboring an active group II intron. The present invention also provides compositions and methods for inhibiting group II intron splicing for inhibiting, preventing or reducing growth of an organism harboring an active group II intron.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: August 29, 2023
    Assignee: YALE UNIVERSITY
    Inventors: Anna Pyle, Olga Fedorova, Erik Gunnar Jagdmann, Michael Van Zandt, Lin Yuan, Albert DeBerardinis
  • RIG-I AGONISTS AND METHODS USING SAME
    Publication number: 20230201242
    Abstract: The present invention provides combination therapies that are useful for treating and/or preventing certain cancers. In certain embodiments, the therapy comprises an immune-checkpoint inhibitor and a RIG-I agonist. In other embodiments, the therapy comprises a RIG-I agonist.
    Type: Application
    Filed: July 13, 2022
    Publication date: June 29, 2023
    Inventors: Akiko Iwasaki, Anna Marie Pyle, Xiaodong Jiang, Olga Fedorova
  • RIG-I Agonists and Methods of Using Same
    Publication number: 20230159923
    Abstract: The present invention provides RIG-I agonists. In certain embodiments, the agonists of the invention can be used to induce a type I interferon response in a cell.
    Type: Application
    Filed: August 29, 2022
    Publication date: May 25, 2023
    Inventors: Anna Marie Pyle, Olga Fedorova
  • RIG-I Agonists and Treatments Using Same
    Publication number: 20210260093
    Abstract: The present invention provides combination therapies that are useful for treating and/or preventing certain cancers. In certain embodiments, the therapy comprises an immune-checkpoint inhibitor and a RIG-I agonist. In other embodiments, the therapy comprises a RIG-I agonist.
    Type: Application
    Filed: June 20, 2019
    Publication date: August 26, 2021
    Inventors: Akiko Iwasaki, Anna Marie Pyle, Xiaodong Jiang, Olga Fedorova
  • RIG-I Agonists and Methods of Using Same
    Publication number: 20210230596
    Abstract: The present invention provides RIG-I agonists. In certain embodiments, the agonists of the invention can be used to induce a type I interferon response in a cell.
    Type: Application
    Filed: April 8, 2021
    Publication date: July 29, 2021
    Inventors: Anna Marie Pyle, Olga Fedorova
  • COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA
    Publication number: 20210139512
    Abstract: The present invention provides compositions and methods for inhibiting group II intron splicing for treating or preventing a disease or disorder associated with an organism harboring an active group II intron. The present invention also provides compositions and methods for inhibiting group II intron splicing for inhibiting, preventing or reducing growth of an organism harboring an active group II intron.
    Type: Application
    Filed: January 25, 2019
    Publication date: May 13, 2021
    Inventors: Anna Pyle, Olga Fedorova, Erik Gunnar Jagdmann, Michael Van Zandt, Lin Yuan, Albert DeBerardinis
  • RIG-I AGONISTS AND METHODS USING SAME
    Publication number: 20200061097
    Abstract: The present invention provides combination therapies that are useful for treating and/or preventing certain cancers. In certain embodiments, the therapy comprises an immune-checkpoint inhibitor and a RIG-I agonist. In other embodiments, the therapy comprises a RIG-I agonist.
    Type: Application
    Filed: September 3, 2019
    Publication date: February 27, 2020
    Inventors: Akiko Iwasaki, Anna Marie Pyle, Xiaodong Jiang, Olga Fedorova