Patents by Inventor Olga Genbacev-Krtolica

Olga Genbacev-Krtolica has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7175990
    Abstract: The present invention provides a method of predicting the probability of a successful pregnancy, either a naturally achieved pregnancy or a pregnancy resulting from an assisted reproductive technology, based on the level of L-selectin ligand expressed by uterine epithelial cells and/or the level of L-selectin expressed by an embryo in vitro. The invention further provides methods of inhibiting cell adhesion between a trophoblast and a uterine epithelial cell. Methods of inhibiting cell adhesion between a trophoblast and a uterine epithelial cell are useful to inhibit pregnancy. The invention further provides methods of assessing in vitro embryo quality. The invention further provides methods of predicting the probability of continued success of a pregnancy during the first 16 weeks of gestation.
    Type: Grant
    Filed: February 25, 2003
    Date of Patent: February 13, 2007
    Assignee: The Regents of the University of California
    Inventors: Susan J. Fisher, Olga Genbacev-Krtolica, Akraporn Prakobphol, Michael T. McMaster
  • Publication number: 20030219836
    Abstract: The present invention provides a method of predicting the probability of a successful pregnancy, either a naturally achieved pregnancy or a pregnancy resulting from an assisted reproductive technology, based on the level of L-selectin ligand expressed by uterine epithelial cells and/or the level of L-selectin expressed by an embryo in vitro. The invention further provides methods of inhibiting cell adhesion between a trophoblast and a uterine epithelial cell. Methods of inhibiting cell adhesion between a trophoblast and a uterine epithelial cell are useful to inhibit pregnancy. The invention further provides methods of assessing in vitro embryo quality. The invention further provides methods of predicting the probability of continued success of a pregnancy during the first 16 weeks of gestation.
    Type: Application
    Filed: February 25, 2003
    Publication date: November 27, 2003
    Inventors: Susan J. Fisher, Olga Genbacev-Krtolica, Akraporn Prakobphol, Michael T. McMaster