Patents by Inventor Olga K. Kosheleva

Olga K. Kosheleva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF ENHANCING THE ACCURACY AND/OR SENSITIVITY OF ULTRASOUND IMAGING IN DIAGNOSING TUMORS
    Publication number: 20210113179
    Abstract: Disclosed herein is a method of enhancing the accuracy and/or sensitivity of ultrasound imaging in detecting a tumor in a subject. The method comprises administering to the subject an effective amount of a nanoparticle prior to the application of ultrasound to the subject. According to certain embodiments of the present disclosure, the nanoparticle is a magnetic nanoparticle, for example, a gold, silver, or iron oxide nanoparticle. Also disclosed herein are methods of treating a tumor in a subject by detecting the tumor via ultrasound with the aid of a nanoparticle, and then administering to the subject an anti-cancer treatment based on the location of the tumor revealed by the ultrasound image.
    Type: Application
    Filed: October 19, 2020
    Publication date: April 22, 2021
    Applicants: Academia Sinica, National Chiao Tung University
    Inventors: Chung-Hsuan CHEN, Shok-Li NG, Yung-Chieh CHAN, Peter LAI, Michael HSIAO, Olga K KOSHELEVA, Nelson G. CHEN
  • Nanoparticle-assisted ultrasound for breast cancer therapy
    Patent number: 9427466
    Abstract: Methods for reducing the growth of breast cancer cells in a subject by exposing the cells to nanoparticles, and irradiating with a focused, low to medium power ultrasound. The nanoparticles can be gold or magnetic nanoparticles. The nanoparticles can have a cancer drug attached, such as an antibody-based cancer drug.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: August 30, 2016
    Assignee: Academia Sinica
    Inventors: Olga K. Kosheleva, Peter Lai, Nelson G. Chen, Michael Hsiao, Chung-Hsuan Chen
  • NANOPARTICLE-ASSISTED ULTRASOUND FOR BREAST CANCER THERAPY
    Publication number: 20150328485
    Abstract: Methods for reducing the growth of breast cancer cells in a subject by exposing the cells to nanoparticles, and irradiating with a focused, low to medium power ultrasound. The nanoparticles can be gold or magnetic nanoparticles. The nanoparticles can have a cancer drug attached, such as an antibody-based cancer drug.
    Type: Application
    Filed: July 24, 2015
    Publication date: November 19, 2015
    Inventors: Olga K. Kosheleva, Peter Lai, Nelson G. Chen, Michael Hsiao, Chung-Hsuan Chen
  • Nanoparticle-assisted ultrasound for cancer therapy
    Patent number: 9138476
    Abstract: Methods for killing cancer cells and treating cancer in a subject by exposing the cells to nanoparticles, and irradiating with a focused, low to medium power ultrasound. The nanoparticles can be gold, iron oxide, copper, silver, polystyrene, PEG, or liposome nanoparticles. The nanoparticles can have a cancer drug attached, such as an antibody-based cancer drug.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: September 22, 2015
    Assignee: Academia Sinica
    Inventors: Olga K. Kosheleva, Peter Lai, Nelson G. Chen, Michael Hsiao, Chung-Hsuan Chen
  • NANOPARTICLE-ASSISTED ULTRASOUND FOR CANCER THERAPY
    Publication number: 20140335156
    Abstract: Methods for killing cancer cells and treating cancer in a subject by exposing the cells to nanoparticles, and irradiating with a focused, low to medium power ultrasound. The nanoparticles can be gold, iron oxide, copper, silver, polystyrene, PEG, or liposome nanoparticles. The nanoparticles can have a cancer drug attached, such as an antibody-based cancer drug.
    Type: Application
    Filed: April 16, 2014
    Publication date: November 13, 2014
    Applicant: Academia Sinica
    Inventors: Olga K. Kosheleva, Peter Lai, Nelson G. Chen, Michael Hsiao, Chung-Hsuan Chen