Patents by Inventor Olga Minenkova

Olga Minenkova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FIMH VACCINE AGAINST URINARY TRACT INFECTIONS (UTI)
    Publication number: 20130122033
    Abstract: A engineered bacteriophage is herein described, displaying at its surface multiple copies of a polypeptide, which comprises a domain of the bacterial adhesion protein FimH fused with the coat protein pVIII. The domain is preferably the region 45-159aa of the mature protein FimH. The polypeptide beingantigenic, raises a desired immunological response, in particular against urinary tract infections (UTI) in a human or animal. The engineered bacteriophage is therefore suitable for the preparation of vaccinesfor therapy, diagnosis and/or prevention of urinary tract infections (UTI) in a human or animal.
    Type: Application
    Filed: June 28, 2011
    Publication date: May 16, 2013
    Inventors: Rita De Santis, Olga Minenkova
  • Vector for efficient selection and/or maturation of an antibody and uses thereof
    Patent number: 8003383
    Abstract: It is described a vector suitable for efficient selection and/or maturation of a recombinant antibody characterized in that it contains at least one element able to reduce the expression level and/or has an improved efficiency of display of said recombinant antibody.
    Type: Grant
    Filed: December 27, 2006
    Date of Patent: August 23, 2011
    Assignees: Sigma Tau Industrie Farmaceutiche Riunite S.pA., Tecnogen S.p.A.
    Inventors: Olga Minenkova, Emiliano Pavoni
  • Vector for Efficient Selection and/or Maturation of an Antibody and Uses Thereof
    Publication number: 20080286274
    Abstract: It is described a vector suitable for efficient selection and/or maturation of a recombinant antibody characterized in that it contains at least one element able to reduce the expression level and/or has an improved efficiency of display of said recombinant antibody.
    Type: Application
    Filed: December 27, 2006
    Publication date: November 20, 2008
    Inventors: Olga Minenkova, Emiliano Pavoni
  • Identification of specific tumour antigens by means of the selection of cdna libraries with sera and the use of said antigens in diagnostic imaging techniques
    Publication number: 20050084857
    Abstract: A method is described for the identification of specific tumor antigens by means of the selection of cDNA display libraries by using sera, characterised in that said selection is accomplished with the phage display technique, and in particular said selection is accomplished by means of the SEREX technique (serological analysis of autologous tumor antigens through the expression of recombinant cDNA). The method according to the invention described herein advantageously combines the SEREX approach with the potency of the phage display technique defined above, at the same time avoiding the drawbacks characteristic of the SEREX technique. The so identified antigens are useful for the preparation of medicaments for the treatment of tumors.
    Type: Application
    Filed: July 25, 2002
    Publication date: April 21, 2005
    Applicant: Kenton S.R.L.
    Inventors: Franco Felici, Olga Minenkova
  • Identification of specific tumor antigens by means of the selection of cdna libraries with sera and the use of said antigena in the treatment of tumors
    Publication number: 20050069556
    Abstract: A method is described for the identification of specific tumour antigens by means of the selection of CND display libraries by using sera, characterised in that said selection is accomplished with the phage display technique, and in particular said selection is accomplished by means of the SEREX technique (serological analysis of autologous tumor antigens through the expression of recombinant cDNA). The method according to the invention described herein advantageously combines the SEREX approach with the potency of the phage display technique defined above, at the same time avoiding the drawbacks characteristic of the SEREX technique. The so identified antigens are useful for the preparation of medicaments for the treatment of tumors.
    Type: Application
    Filed: July 25, 2002
    Publication date: March 31, 2005
    Inventors: Franco Felici, Olga Minenkova
  • Vector for efficient selection and/or maturation of an antibody and uses thereof
    Patent number: RE45968
    Abstract: It is described a vector suitable for efficient selection and/or maturation of a recombinant antibody characterized in that it contains at least one element able to reduce the expression level and/or has an improved efficiency of display of said recombinant antibody.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: April 12, 2016
    Assignee: SIGMA TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
    Inventors: Olga Minenkova, Emiliano Pavoni