Patents by Inventor Olga Pakhomova

Olga Pakhomova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Electroporation-induced electrosensitization
    Patent number: 11820976
    Abstract: Systems and methods of enhancing membrane permeabilization in a cell are provided. An example method includes disposing the cell between a first electrode and a second electrode and applying a plurality of electrical pulses between the first electrode and the second electrode. In the systems and methods, the plurality of electrical pulses include at least two trains of pulses separated by an interval greater than about 10 s. Further, the amplitude of the electrical pulses is selected to be greater than about 0.2 kV/cm.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: November 21, 2023
    Assignee: Old Dominion University Research Foundation
    Inventors: Olga Pakhomova, Andrei G. Pakhomov
  • ELECTROPORATION-INDUCED ELECTROSENSITIZATION
    Publication number: 20210214712
    Abstract: Systems and methods of enhancing membrane permeabilization in a cell are provided. An example method includes disposing the cell between a first electrode and a second electrode and applying a plurality of electrical pulses between the first electrode and the second electrode. In the systems and methods, the plurality of electrical pulses include at least two trains of pulses separated by an interval greater than about 10 s. Further, the amplitude of the electrical pulses is selected to be greater than about 0.2 kV/cm.
    Type: Application
    Filed: March 29, 2021
    Publication date: July 15, 2021
    Inventors: Olga Pakhomova, Andrei G. Pakhomov
  • Electroporation-induced electrosensitization
    Patent number: 10982206
    Abstract: Methods of enhancing membrane permeabilization in a cell are provided. A method includes disposing the cell between a first electrode and a second electrode and applying a plurality of electrical pulses between the first electrode and the second electrode. In the method, the plurality of electrical pulses include at least two trains of pulses separated by an interval greater than about 10 s. Further, the amplitude of the electrical pulses is selected to be greater than about 0.2 kV/cm.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: April 20, 2021
    Assignee: Old Dominion University Research Foundation
    Inventors: Olga Pakhomova, Andrei G. Pakhomov
  • Electroporation-induced electrosensitization
    Patent number: 10131900
    Abstract: Methods of enhancing membrane permeabilization in a cell are provided. A method includes disposing the cell between a first electrode and a second electrode and applying a plurality of electrical pulses between the first electrode and the second electrode. In the method, the plurality of electrical pulses include at least two trains of pulses separated by an interval greater than about 10 s. Further, the amplitude of the electrical pulses is selected to be greater than about 0.2 kV/cm.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: November 20, 2018
    Assignee: OLD DOMINION UNIVERSITY RESEARCH FOUNDATION
    Inventors: Olga Pakhomova, Andrei G. Pakhomov
  • ELECTROPORATION-INDUCED ELECTROSENSITIZATION
    Publication number: 20180251753
    Abstract: Methods of enhancing membrane permeabilization in a cell are provided. A method includes disposing the cell between a first electrode and a second electrode and applying a plurality of electrical pulses between the first electrode and the second electrode. In the method, the plurality of electrical pulses include at least two trains of pulses separated by an interval greater than about 10 s. Further, the amplitude of the electrical pulses is selected to be greater than about 0.2 kV/cm.
    Type: Application
    Filed: May 7, 2018
    Publication date: September 6, 2018
    Inventors: Olga PAKHOMOVA, Andrei G. PAKHOMOV
  • ELECTROPORATION-INDUCED ELECTROSENSITIZATION
    Publication number: 20130260435
    Abstract: Methods of enhancing membrane permeabilization in a cell are provided. A method includes disposing the cell between a first electrode and a second electrode and applying a plurality of electrical pulses between the first electrode and the second electrode. In the method, the plurality of electrical pulses include at least two trains of pulses separated by an interval greater than about 10 s. Further, the amplitude of the electrical pulses is selected to be greater than about 0.2 kV/cm.
    Type: Application
    Filed: December 13, 2011
    Publication date: October 3, 2013
    Applicant: OLD DOMINION UNIVERSITY RESEARCH FOUNDATION
    Inventors: Olga Pakhomova, Andrei G. Pakhomov