Patents by Inventor Olga Schöne

Olga Schöne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of carbamoylamino pyrazole derivatives
    Patent number: 10351533
    Abstract: The present invention relates to a process for the preparation of carbamoylamino pyrazole derivatives using diacetoxyiodobenzene (PhI(OAc)2) in combination with a non-nucleophilic base.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: July 16, 2019
    Assignee: Sandoz AG
    Inventors: Olga Schöne, Hans-Peter Spitzenstätter, Marius Kaufmann
  • Sofosbuvir Derivatives for the Treatment of Hepatitis C
    Publication number: 20190185507
    Abstract: The present invention relates to novel compounds for the treatment of Hepatitis C.
    Type: Application
    Filed: August 17, 2017
    Publication date: June 20, 2019
    Applicant: Sandoz AG
    Inventors: George Moore, Desiree Strych, Michael Papp, Olga Schoene, Thorsten Wilhelm, Hannes Lengauer
  • Synthesis of phosphoramidates
    Patent number: 10160779
    Abstract: A process for preparing a compound of formula (I) or a salt thereof, the process comprising providing a compound of formula (III) wherein PG is an inert electron withdrawing hydroxyl protecting group, reacting the compound of formula (III) with a fluorinating agent, obtaining a compound of formula (II) and deprotecting the compound of formula (II).
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: December 25, 2018
    Assignee: Sandoz AG
    Inventors: Olga Schöne, Thorsten Wilhelm
  • Process for the Preparation of Carbamoylamino Pyrazole Derivatives
    Publication number: 20180305319
    Abstract: The present invention relates to a process for the preparation of carbamoylamino pyrazole derivatives using diacetoxyiodobenzene (PhI(OAc)2) in combination with a non-nucleophilic base.
    Type: Application
    Filed: June 28, 2016
    Publication date: October 25, 2018
    Applicant: Sandoz AG
    Inventors: Olga SCHÖNE, Hans-Peter Spitzenstätter, Marius KAUFMANN
  • Synthesis of Phosphoramidates
    Publication number: 20180298045
    Abstract: A process for preparing a compound of formula (I) or a salt thereof, the process comprising providing a compound of formula (III) wherein PG is an inert electron withdrawing hydroxyl protecting group, reacting the compound of formula (III) with a fluorinating agent, obtaining a compound of formula (II) and deprotecting the compound of formula (II).
    Type: Application
    Filed: June 22, 2016
    Publication date: October 18, 2018
    Applicant: Sandoz AG
    Inventors: Olga SCHÖNE, Thorsten WILHELM
  • Synthesis of Phosphoramidates
    Publication number: 20180162896
    Abstract: A process for preparing a nucleoside phosphoramidate, in particular to a process for preparing sofosbuvir, wherein a phosphoramidate derivative is used as starting material.
    Type: Application
    Filed: May 26, 2016
    Publication date: June 14, 2018
    Applicant: Sandoz AG
    Inventors: Thorsten Wilhelm, Olga Schöne, Hans-Peter Spitzenstätter
  • Synthesis of Phosphoramidates
    Publication number: 20170218006
    Abstract: A process for the preparation of a compound of formula (I) including all isomers, stereoisomers, enantiomers and diastereomers thereof (I), and salts thereof; the process comprising providing a mixture comprising a compound of formula (II) and a compound of formula (III) subjecting the mixture provided in a) to reaction conditions in the presence of one or more Lewis acids to the mixture provided in a), obtaining a mixture comprising the compound of formula (I).
    Type: Application
    Filed: July 31, 2015
    Publication date: August 3, 2017
    Applicant: Sandoz AG
    Inventors: Thorsten Wilhelm, Hans-Peter Spitzenstätter, Olga Schöne, Frank Richter, Erwin Schreiner