Patents by Inventor Olga Timofeeva

Olga Timofeeva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods And Compositions For Cancer Therapies That Include Delivery Of Halogenated Thymidines And Thymidine Phosphorylase Inhibitors In Combination With Radiation
    Publication number: 20230302034
    Abstract: Methods and formulations are provided for treating cancer and neoplastic diseases in conjunction with radiation therapy where such methods and formulations include a combination of a radiosensitizing agent that is metabolized by thymidine phosphorylase and a thymidine phosphorylase inhibitor that increases the half-life of the radiosensitizing agent.
    Type: Application
    Filed: April 2, 2023
    Publication date: September 28, 2023
    Inventors: Scott Grindrod, Mira Jung, Olga Timofeeva, Milton Brown, Anatoly Dritschilo
  • Methods and compositions for cancer therapies that include delivery of halogenated thymidines and thymidine phosphorylase inhibitors in combination with radiation
    Patent number: 11654157
    Abstract: Methods and formulations are provided for treating cancer and neoplastic diseases in conjunction with radiation therapy where such methods and formulations include a combination of a radiosensitizing agent that is metabolized by thymidine phosphorylase and a thymidine phosphorylase inhibitor that increases the half-life of the radiosensitizing agent.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: May 23, 2023
    Assignee: Shuttle Pharmaceuticals, Inc.
    Inventors: Scott Grindrod, Mira Jung, Olga Timofeeva, Milton Brown, Anatoly Dritschilo
  • Methods And Compositions For Cancer Therapies That Include Delivery Of Halogenated Thymidines And Thymidine Phosphorylase Inhibitors In Combination With Radiation
    Publication number: 20190343859
    Abstract: Methods and formulations are provided for treating cancer and neoplastic diseases in conjunction with radiation therapy where such methods and formulations include a combination of a radiosensitizing agent that is metabolized by thymidine phosphorylase and a thymidine phosphorylase inhibitor that increases the half-life of the radiosensitizing agent.
    Type: Application
    Filed: January 9, 2018
    Publication date: November 14, 2019
    Inventors: Scott Grindrod, Mira Jung, Olga Timofeeva, Milton Brown, Anatoly Dritschilo
  • PEPTIDE-BASED STAT INHIBITOR
    Publication number: 20170204148
    Abstract: A peptide or peptidomimetic comprising the amino acid sequence of the second helix of a STAT protein, or a variant of such sequence, wherein the peptide or peptidomimetic comprises about 40 or fewer amino acids and binds to a STAT protein, as well as a method of inhibiting a STAT protein in a cell, a method of treating or preventing a disease associated with STAT overexpression in a host, and related compounds, compositions, and methods.
    Type: Application
    Filed: January 3, 2017
    Publication date: July 20, 2017
    Inventors: Nadya I. Tarasova, Olga Timofeeva, Vadim Gaponenko, Alan O. Perantoni, Sergey G. Tarasov, Christopher J. Michejda
  • Peptide-based stat inhibitor
    Patent number: 9540427
    Abstract: A peptide or peptidomimetic comprising the amino acid sequence of the second helix of a STAT protein, or a variant of such sequence, wherein the peptide or peptidomimetic comprises about 40 or fewer amino acids and binds to a STAT protein, as well as a method of inhibiting a STAT protein in a cell, a method of treating or preventing a disease associated with STAT overexpression in a host, and related compounds, compositions, and methods.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: January 10, 2017
    Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Nadya I. Tarasova, Olga Timofeeva, Vadim Gaponenko, Christopher J. Michejda, Maria Michejda, Alan O. Perantoni, Sergey G. Tarasov
  • PEPTIDE-BASED STAT INHIBITOR
    Publication number: 20100184697
    Abstract: A peptide or peptidomimetic comprising the amino acid sequence of the second helix of a STAT protein, or a variant of such sequence, wherein the peptide or peptidomimetic comprises about 40 or fewer amino acids and binds to a STAT protein, as well as a method of inhibiting a STAT protein in a cell, a method of treating or preventing a disease associated with STAT overexpression in a host, and related compounds, compositions, and methods.
    Type: Application
    Filed: May 30, 2008
    Publication date: July 22, 2010
    Applicant: THE U.S OF AMERICA, AS REPRESENTED BY THE SECRETAR
    Inventors: Nadya I. Tarasova, Olga Timofeeva, Vadim Gaponenko, Christopher J. Michejda, Maria Michejda, Alan O. Perantoni, Sergey G. Tarasov