Patents by Inventor Olha Voznyuk Wuerthinger

Olha Voznyuk Wuerthinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of making a polymersome
    Patent number: 11999829
    Abstract: The present invention provides polymersomes comprising amphiphilic block-copolymers and their use to quantify ammonia in samples (e.g., body fluid samples). More particularly, it provides a polymersome comprising (a) a membrane, which comprises a block copolymer of poly(styrene) (PS) and poly(ethylene oxide) (PEO), wherein the PS/PEO molecular weight ratio is higher than 1.0 and lower than 4.0; and (b) a core which encloses an acid and at least one pH-sensitive dye. Compositions, strips and kits comprising the polymersomes are also provided along with methods of quantifying ammonia in a sample using the polymersomes, compositions and kit.
    Type: Grant
    Filed: March 20, 2023
    Date of Patent: June 4, 2024
    Assignee: ETH ZURICH
    Inventors: Jean-Christophe Leroux, Simon Matoori, Olha Voznyuk Wuerthinger
  • TRANSMEMBRANE pH-GRADIENT POLYMERSOMES
    Publication number: 20230303778
    Abstract: The present invention provides polymersomes comprising amphiphilic block-copolymers and their use to quantify ammonia in samples (e.g., body fluid samples). More particularly, it provides a polymersome comprising (a) a membrane, which comprises a block copolymer of poly(styrene) (PS) and poly(ethylene oxide) (PEO), wherein the PS/PEO molecular weight ratio is higher than 1.0 and lower than 4.0; and (b) a core which encloses an acid and at least one pH-sensitive dye. Compositions, strips and kits comprising the polymersomes are also provided along with methods of quantifying ammonia in a sample using the polymersomes, compositions and kit.
    Type: Application
    Filed: June 2, 2023
    Publication date: September 28, 2023
    Inventors: Jean-Christophe Leroux, Simon Matoori, Olha Voznyuk Wuerthinger
  • Transmembrane pH-gradient polymersomes for the quantification of ammonia in body fluids
    Patent number: 11713376
    Abstract: The present invention provides polymersomes comprising amphiphilic block-copolymers and their use to quantify ammonia in samples (e.g., body fluid samples). More particularly, it provides a polymersome comprising (a) a membrane, which comprises a block copolymer of poly(styrene) (PS) and poly(ethylene oxide) (PEO), wherein the PS/PEO molecular weight ratio is higher than 1.0 and lower than 4.0; and (b) a core which encloses an acid and at least one pH-sensitive dye. Compositions, strips and kits comprising the polymersomes are also provided along with methods of quantifying ammonia in a sample using the polymersomes, compositions and kit.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: August 1, 2023
    Assignee: ETH ZURICH
    Inventors: Jean-Christophe Leroux, Simon Matoori, Olha Voznyuk Wuerthinger
  • METHOD OF MAKING A POLYMERSOME
    Publication number: 20230220165
    Abstract: The present invention provides polymersomes comprising amphiphilic block-copolymers and their use to quantify ammonia in samples (e.g., body fluid samples). More particularly, it provides a polymersome comprising (a) a membrane, which comprises a block copolymer of poly(styrene) (PS) and poly(ethylene oxide) (PEO), wherein the PS/PEO molecular weight ratio is higher than 1.0 and lower than 4.0; and (b) a core which encloses an acid and at least one pH-sensitive dye. Compositions, strips and kits comprising the polymersomes are also provided along with methods of quantifying ammonia in a sample using the polymersomes, compositions and kit.
    Type: Application
    Filed: March 20, 2023
    Publication date: July 13, 2023
    Inventors: Jean-Christophe Leroux, Simon Matoori, Olha Voznyuk Wuerthinger
  • TRANSMEMBRANE PH-GRADIENT POLYMERSOMES FOR THE QUANTIFICATION OF AMMONIA IN BODY FLUIDS
    Publication number: 20200283583
    Abstract: The present invention provides polymersomes comprising amphiphilic block-copolymers and their use to quantify ammonia in samples (e.g., body fluid samples). More particularly, it provides a polymersome comprising (a) a membrane, which comprises a block copolymer of poly(styrene) (PS) and poly(ethylene oxide) (PEO), wherein the PS/PEO molecular weight ratio is higher than 1.0 and lower than 4.0; and (b) a core which encloses an acid and at least one pH-sensitive dye. Compositions, strips and kits comprising the polymersomes are also provided along with methods of quantifying ammonia in a sample using the polymersomes, compositions and kit.
    Type: Application
    Filed: September 10, 2018
    Publication date: September 10, 2020
    Inventors: Jean-Christophe Leroux, Simon Matoori, Olha Voznyuk Wuerthinger