Abstract: The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Abstract: A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.

Abstract: The invention relates to an automated hand, such as a prosthetic hand. In one form, the automated hand may be fluid compatible. In one form, the automated hand may comprise features to reduce the risk of harm to motors and/or other sensitive components of the hand when subject to an impact. In one form, the hand may comprise a wrist joint configured to allow the hand to curl and flex and/or to rotate. In one form, one or more digits of the hand may be individually controlled. In one form the hand may include a thumb rotation locking mechanism. In one form the hand may be provided with removable grip plates. In one form, the hand May be configured for use as a training hand.

Abstract: Data collection devices for attachment to injection devices are disclosed. In one embodiment, the data collection device includes: a body attachable to a dial member of the injection device, a sensor arrangement comprising a sensor and a scale, and a processor. The sensor is configured to detect a rotation of the body relative to a trigger of the injection device. The processor is configured to detect a rotation of the body relative to the trigger. One of the sensor and the scale is arranged in or on the body and wherein the other one of the sensor and the scale is located on the trigger or is rotationally lockable to the trigger configured to detect a rotation of the body relative to the trigger.

Abstract: A drug delivery device for setting and dispensing doses of a liquid drug is described. The device includes a housing and a dose setting and drive mechanism with a dose setting member and a dose setting drum. The dose setting and drive mechanism is configured to perform a dose setting operation for setting a dose to be delivered by the drug delivery device by rotating the dose setting member relative to the housing and a dose delivery operation for delivering the set dose during rotation of the dose setting drum relative to dose setting member the housing. The dose setting drum includes an array of encoder features at its proximal end. The dose setting member has at least one aperture located in a proximal end surface that is coincident with at least a portion of the array of encoder features of the dose setting drum.

Abstract: The present disclosure relates to a drug delivery device for setting and dispensing doses of a liquid drug. The device comprises a housing and a dose setting and drive mechanism with a dose setting member. The dose setting and drive mechanism is, at least partially, arranged within the housing and is configured to perform a dose setting operation for selecting a dose to be delivered by the drug delivery device by moving the dose setting member relative to the housing and a dose delivery operation for delivering the set dose by axially displacing the dose setting member along an axis. The maximum radial extension perpendicular to the axis of the dose setting member is smaller than the maximum radial extension of a region of the housing located adjacent to the dose setting member.

Abstract: A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.

Abstract: The present disclosure refers to a drug delivery device for setting and dispensing doses of a liquid drug which may be used together with a module for detecting the amount of a dose selected and/or delivered. The device comprises a housing and a dose setting and drive mechanism with a dose setting member. The dose setting and drive mechanism is configured to perform a dose setting operation for selecting a dose to be delivered by rotating the dose setting member relative to the housing and a dose delivery operation for delivering the set dose by pushing the dose setting member axially towards the housing without relative rotation therebetween. The dose setting member comprises a set of axially directed stop teeth formed at its distal end which are configured to engage with a set of counterstop teeth located on the housing at the end of the dose delivery operation.

Abstract: A drug delivery device for setting and dispensing doses of a liquid drug. The device comprises a housing and a dose setting and drive mechanism with a dose setting member and a dose setting drum. The dose setting and drive mechanism is configured to perform a dose setting operation for selecting a dose to be delivered, and a dose delivery operation for delivering the set dose. The dose setting drum comprises a set of clutch teeth that are engagable with a mating set of teeth on the dose setting member. The clutch teeth and the mating teeth are engaged during a dose setting operation to prevent rotation therebetween and the clutch teeth and the mating teeth are disengaged during a dose delivery operation allowing relative rotation between the dose setting drum and the dose setting member. The clutch teeth are formed on an external surface of the dose setting drum.

Abstract: The invention relates to an automated hand, such as a prosthetic hand. In one form, the automated hand may be fluid compatible. In one form, the automated hand may comprise features to reduce the risk of harm to motors and/or other sensitive components of the hand when subject to an impact. In one form, the hand may comprise a wrist joint configured to allow the hand to curl and flex and/or to rotate. In one form, one or more digits of the hand may be individually controlled. In one form the hand may include a thumb rotation locking mechanism. In one form the hand may be provided with removable grip plates. In one form, the hand may be configured for use as a training hand.

Abstract: The disclosure relates to an injection device for setting and injecting pre-set or user-selectable doses of a medicament, the injection device comprising an elongated housing defining a longitudinal direction and configured to accommodate a cartridge containing the medicament, and a detector arrangement operable to detect a relative movement between a first element and a second element. The first element is subject to a first movement relative to the second element along a first longitudinal direction for setting of a dose, the first element is subject to a second movement relative to the second element along a second longitudinal direction for dispensing of the dose, one of the first movement and the second movement is a helical movement, and the other one of the first movement and the second movement is a sliding movement in the longitudinal direction. The second element comprises at least one reference element fixed to the second element.

Abstract: The invention relates to an automated hand, such as a prosthetic hand. In one form, the automated hand may be fluid compatible. In one form, the automated hand may comprise features to reduce the risk of harm to motors and/or other sensitive components of the hand when subject to an impact. In one form, the hand may comprise a wrist joint configured to allow the hand to curl and flex and/or to rotate. In one form, one or more digits of the hand may be individually controlled. In one form the hand may include a thumb rotation locking mechanism. In one form the hand may be provided with removable grip plates. In one form, the hand may be configured for use as a training hand.

Abstract: The disclosure relates to an injection device for setting and injecting pre-set or user-selectable doses of a medicament, the injection device comprising an elongated housing defining a longitudinal direction and configured to accommodate a cartridge containing the medicament, and a detector arrangement operable to detect a relative movement between a first element and a second element. The first element is subject to a first movement relative to the second element along a first longitudinal direction for setting of a dose, the first element is subject to a second movement relative to the second element along a second longitudinal direction for dispensing of the dose, one of the first movement and the second movement is a helical movement, and the other one of the first movement and the second movement is a sliding movement in the longitudinal direction. The second element comprises at least one reference element fixed to the second element.

Abstract: The present disclosure refers to a drug delivery device and to a method of operating the same. The device includes a housing, a dial grip manually operable by a user for setting an individual dose to be delivered by the device, a dose setting and drive mechanism, a clutch including two clutch members for rotationally coupling and de-coupling the dial grip to the housing and/or to the dose setting and drive mechanism, at least one processor, a sensor arrangement operable to generate measurement data indicative of the dose setting operation, and a power source connected to the at least one processor. The drug delivery device includes a clutch actuator operable by the at least one processor to trigger a switch of the state of the clutch. The at least one processor is configured to operate the clutch actuator if the measurement data generated by the sensor arrangement reaches a threshold.

Abstract: A method for associating dose related data captured with and stored in an add-on device to a drug delivery device by means of an external computing device is described. The method includes: providing a drug delivery device comprising identification information, providing an add-on device, comprising communication means allowing the add-on device to communicate with an external computing device, means for capturing and storing dose related data, wherein the add-on device is adapted to be releasably mounted on and in engagement with the drug delivery device, providing an external computing device comprising, means for receiving the identification information from the drug delivery device, communication means allowing the external control device to communicate with the add-on device, processor means, and storage means comprising a computer program.

Abstract: A needle actuator assembly for a drug delivery system includes a housing, a needle having retracted and extended positions, a needle actuator body received within the housing and configured to move from a pre-use position where the needle is in the retracted position to a use position where the needle is in the extended position and to a post-use position where the needle is in the retracted position, with the needle actuator having a button contact surface, and an actuator button received by the housing.

Abstract: The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Abstract: A dose counting system of an injection device or of a module configured to be used with or applied to an injection device is described. The dose counting system includes a sensor arrangement including a first sensor configured to output a first signal and a second sensor configured to output a second signal; and a processor configured to: detect a peak in the first signal when the first signal has increased by at least a predefined up threshold and the first signal exceeds the value of the second signal by more than a predetermined crossover threshold; determine that a unit of medicament has been administered when the first signal drops from the peak by more than a predefined down threshold and the preceding peak occurred in the second signal; and determine a medicament dosage administered by the injection device by counting the administered units of medicament.

Abstract: A drug delivery system for injecting a medicament includes a housing, a container configured to receive a medicament including a stopper configured to move within the container and a closure, a needle in fluid communication with the container, a spacer configured to be engaged with the stopper, a first plunger, a first spring configured to bias the first plunger in an axial direction, second plunger disposed about the first plunger, a second spring configured to bias the second plunger in an axial direction. The first plunger is configured to move the spacer and the container relative to the housing via the first spring to establish fluid communication between the container and the patient needle, and the second plunger is configured to move the spacer and the stopper relative to the container via the second spring.

Abstract: An electronic system for a drug delivery device is provided, the electronic system comprising at least one user interface member configured to be manipulated by a user for performing a dose operation, e.g.