Patents by Inventor Oliver Cooper
Oliver Cooper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240091745Abstract: A composite oxidation catalyst for use in an exhaust system for treating an exhaust gas produced by a vehicular compression ignition internal combustion engine is disclosed. The composite oxidation catalyst comprises a honeycomb flow-through substrate monolith and two catalyst washcoat zones arranged axially in series on and along the substrate surface.Type: ApplicationFiled: October 25, 2023Publication date: March 21, 2024Inventors: Andrew CHIFFEY, Kieran COLE, Oliver COOPER, Christopher DALY, Lee GILBERT, Robert HANLEY, David MICALLEF, Francois MOREAU, Paul PHILLIPS, George PLATT
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Patent number: 11845064Abstract: A composite oxidation catalyst (18, 20) for use in an exhaust system for treating an exhaust gas produced by a vehicular compression ignition internal combustion engine (30) and upstream of a particulate matter filter (44, 50) in the exhaust system comprises a substrate (5) having a total length L and a longitudinal axis and having a substrate surface extending axially between a first substrate end (I) and a second substrate end (O); and three or more catalyst washcoat zones (1, 2, 3; or 1, 2, 3, 4) arranged axially in series on and along the substrate surface, wherein a first catalyst washcoat zone (1) having a length L1, wherein L1<L, is defined at one end by the first substrate end (I) and at a second end by a first end (19, 21) of a second catalyst washcoat zone (2) having a length L2, wherein L2<L, wherein the first catalyst washcoat zone (1) comprises a first refractory metal oxide support material and two or more platinum group metal components supported thereon comprising both platinum and pallaType: GrantFiled: June 26, 2020Date of Patent: December 19, 2023Inventors: Andrew Chiffey, Kieran John Cole, Oliver Cooper, Christopher Daly, Lee Gilbert, Robert Hanley, David Micallef, Francois Moreau, Paul Phillips, George Platt
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Publication number: 20230322897Abstract: Described herein are compositions and methods for treating a subject having or at risk of developing a neurocognitive disorder, such as Alzheimer's disease or Nasu-Hakola disease. For example, using the compositions and methods of the disclosure, a subject having or at risk of developing a neurocognitive disorder may be administered one or more cells that contain a transgene encoding triggering receptor expressed on myeloid cells two (TREM2), such as a population of CD34+ hematopoietic stem or progenitor cells that express TREM2, thereby treating or preventing the disorder.Type: ApplicationFiled: June 29, 2021Publication date: October 12, 2023Inventors: Chris MASON, Oliver COOPER, Robert PLASSCHAERT
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Publication number: 20230278018Abstract: A compression ignition internal combustion engine (30) for a heavy-duty diesel vehicle comprising an exhaust system (32) comprising a composite oxidation catalyst (12, 42) and a soot filter substrate (44, 50) disposed downstream from the composite oxidation catalyst comprising: a substrate (5), preferably a honeycomb flow-through substrate monolith, having a total length L and a longitudinal axis and having a substrate surface extending axially between a first substrate end (I) and a second substrate end (O); two catalyst washcoat zones (1, 2) arranged axially in series on and along the substrate surface, wherein a first catalyst washcoat zone (1) having a length L1 and comprising a first catalyst washcoat layer (9), wherein L1<L, is defined at one end by the first substrate end (I) and at a second end by a first end (15) of a second catalyst washcoat zone (2) having a length L2 and comprising a second catalyst washcoat layer (11), wherein L2<L, wherein the second catalyst washcoat zone (2) is defined aType: ApplicationFiled: October 13, 2020Publication date: September 7, 2023Inventors: Andrew Francis CHIFFEY, Kieran COLE, Oliver COOPER, Christopher DALY, Lee Alexander GILBERT, Robert HANLEY, David MICALLEF, Francois MOREAU, Paul PHILLIPS, George PLATT
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Publication number: 20230211323Abstract: A composite, zone-coated, dual-use ammonia (AMOX) and nitric oxide oxidation catalyst (12) comprises: a substrate (5) having a total length L and a longitudinal axis and having a substrate surface extending axially between a first substrate end (I) and a second substrate end (O); two or more catalyst washcoat zones (1; 2) comprised of a first catalyst washcoat layer (9) comprising a refractory metal oxide support material and one or more platinum group metal components supported thereon and a second catalyst washcoat layer (11) different from the first catalyst washcoat layer (9) and comprising a refractory metal oxide support material and one or more platinum group metal components supported thereon, which two or more catalyst washcoat zones (1; 2) being arranged axially in series on and along the substrate surface, wherein a first catalyst washcoat zone (1) having a length L1, wherein L1<L, is defined at one end by the first substrate end (I) and at a second end (13) by a first end (15) of a second catalType: ApplicationFiled: October 16, 2020Publication date: July 6, 2023Inventors: Andrew Francis CHIFFEY, Kieran COLE, Oliver COOPER, Christopher DALY, Jonas EDVARDSSON, Lee GILLBERT, Alexander GREEN, Neil GREENHAM, Robert HANLEY, Caitlin Lucy JENKINS, Per MARSH, David MICALLEF, Francois MOREAU, George PLATT, Paul Richard PHILLIPS, James WYLIE
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Publication number: 20220280919Abstract: The present invention relates to a NOx storage material comprising a cerium-based mixed oxide comprising cerium, oxygen, and a first rare earth metal other than cerium, wherein said NOx storage material further comprises a second rare earth metal other than cerium; wherein said first rare earth metal is different to said second rare earth metal; and wherein said second rare earth metal is disposed or supported on the surface of the cerium-based mixed oxide.Type: ApplicationFiled: February 23, 2022Publication date: September 8, 2022Inventors: Yannick Bidal, Alba Castanon Rodriguez, Andrew Chiffey, Oliver Cooper, Jonathan Radcliffe
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Publication number: 20220152589Abstract: A composite oxidation catalyst (18, 20) for use in an exhaust system for treating an exhaust gas produced by a vehicular compression ignition internal combustion engine (30) and upstream of a particulate matter filter (44, 50) in the exhaust system comprises a substrate (5) having a total length L and a longitudinal axis and having a substrate surface extending axially between a first substrate end (I) and a second substrate end (O); and three or more catalyst washcoat zones (1, 2, 3; or 1, 2, 3, 4) arranged axially in series on and along the substrate surface, wherein a first catalyst washcoat zone (1) having a length L1, wherein L1<L, is defined at one end by the first substrate end (I) and at a second end by a first end (19, 21) of a second catalyst washcoat zone (2) having a length L2, wherein L2<L, wherein the first catalyst washcoat zone (1) comprises a first refractory metal oxide support material and two or more platinum group metal components supported thereon comprising both platinum and pallaType: ApplicationFiled: June 26, 2020Publication date: May 19, 2022Inventors: Andrew CHIFFEY, Kieran John COLE, Oliver COOPER, Christopher DALY, Lee GILBERT, Robert HANLEY, David MICALLEF, Francois MOREAU, Paul PHILLIPS, George PLATT
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Publication number: 20220133850Abstract: Described herein are compositions and methods for treating a subject having or at risk of developing a neurocognitive disorder, such as Alzheimer's disease or Nasu-Hakola disease. For example, using the compositions and methods of the disclosure, a subject having or at risk of developing a neurocognitive disorder may be administered one or more cells that contain a transgene encoding triggering receptor expressed on myeloid cells two (TREM2), such as a population of CD34+ hematopoietic stem or progenitor cells that express TREM2, thereby treating or preventing the disorder.Type: ApplicationFiled: January 31, 2020Publication date: May 5, 2022Inventors: Chris MASON, Oliver COOPER, Mark DEANDRADE, Robert PLASSCHAERT, Nico Peter VAN TIL
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Publication number: 20220133808Abstract: Described herein are compositions and methods for treating a patient having or at risk of developing a neurocognitive disorder, such as Alzheimer's disease, Parkinson's disease, and/or a frontotemporal lobar dementia. Using the compositions and methods of the disclosure, a patient, such as an adult human patient, may be provided one or more agents that elevate the expression and/or activity levels of a protein or series of proteins whose deficiency is associated with the corresponding disease. Exemplary agents that may be used in conjunction with the compositions and methods of the disclosure for this purpose include cells, such as cells, that contain nucleic acids encoding the protein or proteins of interest, as well as vectors, such as viral vectors, encoding the protein or proteins of interest. Additional examples of such agents include the protein or proteins themselves, as well as interfering RNA molecules that stimulate their endogenous expression.Type: ApplicationFiled: January 31, 2020Publication date: May 5, 2022Inventors: Chris MASON, Oliver COOPER, Mark DEANDRADE, Robert PLASSCHAERT, Nico Peter (Niek) VAN TIL
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Publication number: 20220111005Abstract: Described herein are methods for treating a subject having or at risk of developing a neurocognitive disorder, such as frontotemporal lobar degeneration or neuronal ceroid lipofuscinosis, by administering cells that contain a transgene encoding a progranulin (PGRN) or a granulin (GRN) or cells that express the PGRN or the GRN to the subject. Also disclosed are compositions comprising cells containing the transgene encoding the PGRN or the GRN.Type: ApplicationFiled: January 31, 2020Publication date: April 14, 2022Applicants: AvroBio, Inc., AvroBio, Inc.Inventors: Chris MASON, Oliver COOPER, Mark DEANDRADE, Robert PLASSCHAERT, Nico Peter (Niek) VAN TIL
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Publication number: 20210000929Abstract: Described herein are methods for treating a subject having or at risk of developing Parkinson's disease, by administering pluripotent cells that express glucocerebrosidase (GBA) or pluripotent cells that express GBA and one or more M2-promoting agents to the subject. Also disclosed are compositions comprising pluripotent cells expressing GBA, such as pluripotent cells expressing GBA and one or more M2-promoting agents.Type: ApplicationFiled: March 8, 2019Publication date: January 7, 2021Inventors: Chris MASON, Nico Peter VAN TIL, Oliver COOPER
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Publication number: 20190299159Abstract: An oxidation catalyst is described for treating an exhaust gas produced by a diesel engine comprising a catalytic region and a substrate, wherein the catalytic region comprises a catalytic material comprising: bismuth (Bi), antimony (Sb) or an oxide thereof; a platinum group metal (PGM) selected from the group consisting of (i) platinum (Pt), (ii) palladium (Pd) and (iii) platinum (Pt) and palladium (Pd); and a support material, which is a refractory oxide; wherein the platinum group metal (PGM) is supported on the support material; and wherein the bismuth (Bi), antimony (Sb) or an oxide thereof is supported on the support material and/or the refractory oxide comprises the bismuth, antimony or an oxide thereof.Type: ApplicationFiled: June 20, 2019Publication date: October 3, 2019Inventors: Andrew Francis Chiffey, Oliver Cooper, Christopher Daly, Mark Feaviour, Steven Merrick, Francois Moreau, Matthew O'Brien, David Thompsett
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Patent number: 10357743Abstract: An oxidation catalyst is described for treating an exhaust gas produced by a diesel engine comprising a catalytic region and a substrate, wherein the catalytic region comprises a catalytic material comprising: bismuth (Bi), antimony (Sb) or an oxide thereof; a platinum group metal (PGM) selected from the group consisting of (i) platinum (Pt), (ii) palladium (Pd) and (iii) platinum (Pt) and palladium (Pd); and a support material, which is a refractory oxide; wherein the platinum group metal (PGM) is supported on the support material; and wherein the bismuth (Bi), antimony (Sb) or an oxide thereof is supported on the support material and/or the refractory oxide comprises the bismuth, antimony or an oxide thereof.Type: GrantFiled: October 14, 2016Date of Patent: July 23, 2019Assignee: Johnson Matthey Public Limited CompanyInventors: Andrew Francis Chiffey, Oliver Cooper, Christopher Daly, Mark Feaviour, Steven Merrick, Francois Moreau, Matthew O'Brien, David Thompsett
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Publication number: 20190217278Abstract: An oxidation catalyst is described for treating an exhaust gas produced by a diesel engine comprising a catalytic region and a substrate, wherein the catalytic region comprises a catalytic material comprising: bismuth (Bi) or an oxide thereof; an alkaline earth metal or an oxide thereof; a platinum group metal (PGM) selected from the group consisting of (i) platinum (Pt), (ii) palladium (Pd) and (iii) platinum (Pt) and palladium (Pd); and a support material comprising alumina doped with silica in a total amount of 0.5 to 15% by weight of the alumina.Type: ApplicationFiled: January 15, 2019Publication date: July 18, 2019Inventors: Andrew CHIFFEY, Oliver COOPER, Christopher DALY, Francois MOREAU
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Patent number: 9968637Abstract: The present invention provides populations of neural cells derived from pluripotent cells, and methods for making and using the same. Disclosed herein are methods for generating dopaminergic neurons in vitro using a combination of agents that cause differentiation of the pluripotent cells into dopaminergic neurons. Also disclosed are methods for treating a neurodegenerative disease in a patient by generating dopaminergic neurons in vitro, and transplanting them into the brain of the patient, such that the dopaminergic neurons are sufficient to reduce or eliminate the symptoms of the neurodegenerative disease.Type: GrantFiled: May 21, 2015Date of Patent: May 15, 2018Assignee: THE MCLEAN HOSPITAL CORPORATIONInventors: Oliver Cooper, Ole Isacson
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Publication number: 20170106337Abstract: An oxidation catalyst is described for treating an exhaust gas produced by a diesel engine comprising a catalytic region and a substrate, wherein the catalytic region comprises a catalytic material comprising: bismuth (Bi), antimony (Sb) or an oxide thereof; a platinum group metal (PGM) selected from the group consisting of (i) platinum (Pt), (ii) palladium (Pd) and (iii) platinum (Pt) and palladium (Pd); and a support material, which is a refractory oxide: wherein the platinum group metal (PGM) is supported on the support material; and wherein the bismuth (Bi), antimony (Sb) or an oxide thereof is supported on the support material and/or the refractory oxide comprises the bismuth, antimony or an oxide thereof.Type: ApplicationFiled: October 14, 2016Publication date: April 20, 2017Inventors: Andrew Francis CHIFFEY, Oliver COOPER, Christopher DALY, Mark FEAVIOUR, Steven MERRICK, Francois MOREAU, Matthew O'BRIEN, David THOMPSETT
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Publication number: 20150250825Abstract: The present invention provides populations of neural cells derived from pluripotent cells, and methods for making and using the same. Disclosed herein are methods for generating dopaminergic neurons in vitro using a combination of agents that cause differentiation of the pluripotent cells into dopaminergic neurons. Also disclosed are methods for treating a neurodegenerative disease in a patient by generating dopaminergic neurons in vitro, and transplanting them into the brain of the patient, such that the dopaminergic neurons are sufficient to reduce or eliminate the symptoms of the neurodegenerative disease.Type: ApplicationFiled: May 21, 2015Publication date: September 10, 2015Applicant: THE MCLEAN HOSPITAL CORPORATIONInventors: Oliver Cooper, Ole Isacson
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Publication number: 20130108669Abstract: The present invention provides populations of neural cells derived from pluripotent cells, and methods for making and using the same. Disclosed herein are methods for generating dopaminergic neurons in vitro using a combination of agents that cause differentiation of the pluripotent cells into dopaminergic neurons. Also disclosed are methods for treating a neurodegenerative disease in a patient by generating dopaminergic neurons in vitro, and transplanting them into the brain of the patient, such that the dopaminergic neurons are sufficient to reduce or eliminate the symptoms of the neurodegenerative disease.Type: ApplicationFiled: April 15, 2011Publication date: May 2, 2013Applicant: THE MCLEAN HOSPITAL CORPORATIONInventors: Oliver Cooper, Ole Isacson