Patents by Inventor Oliver Dorigo

Oliver Dorigo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for enhanced tumor cell immunity in vivo
    Patent number: 6447769
    Abstract: The invention provides a method of preventing or reducing the severity of a cancer in a subject by stimulating the subject's immune response against the cancer. The invention provides, for example, a method of stimulating an immune response in a subject by administering to the subject tumor cells that are substantially similar to the subject's cancer cells and that are genetically modified to reduce or inhibit the expression of one or more immunosuppressive agents. The invention also provides a method of preventing or reducing the severity of cancer in a subject by stimulating the subject's immune response against the cancer by administering to the subject tumor cells that are substantially similar to the subject's cancer cells and that are genetically modified to prevent the expression of an immunosuppressive agents and, in combination with the genetically modified tumor cells, an immunostimulatory agent.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: September 10, 2002
    Assignee: Sidney Kimmel Cancer Center
    Inventors: Habib Fakhrai, Oliver Dorigo, Robert E. Sobol
  • Compositions and methods for enhanced tumor cell immunity in vivo
    Patent number: 6120763
    Abstract: The invention provides a method of preventing or reducing the severity of a cancer in a subject by stimulating the subject's immune response against the cancer. The invention provides, for example, a method of stimulating an immune response in a subject by administering to the subject tumor cells that are substantially similar to the subject's cancer cells and that are genetically modified to reduce or inhibit the expression of one or more immunosuppressive agents. The invention also provides a method of preventing or reducing the severity of cancer in a subject by stimulating the subject's immune response against the cancer by administering to the subject tumor cells that are substantially similar to the subject's cancer cells and that are genetically modified to prevent the expression of an immunosuppressive agents and, in combination with the genetically modified tumor cells, an immunostimulatory agent. The invention further provides compositions useful for practicing the claimed methods.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: September 19, 2000
    Assignee: Sidney Kimmel Cancer Center
    Inventors: Habib Fakhrai, Oliver Dorigo, Robert E. Sobol
  • Compositions and methods for enhanced tumor cell immunity in vivo
    Patent number: 5772995
    Abstract: The invention provides a method of preventing or reducing the severity of a cancer in a subject by stimulating the subject's immune response against the cancer. The invention provides, for example, a method of stimulating an immune response in a subject by administering to the subject tumor cells that are substantially similar to the subject's cancer cells and that are genetically modified to reduce or inhibit the expression of one or more immunosuppressive agents. The invention also provides a method of preventing or reducing the severity of cancer in a subject by stimulating the subject's immune response against the cancer by administering to the subject tumor cells that are substantially similar to the subject's cancer cells and that are genetically modified to prevent the expression of an immunosuppressive agents and, in combination with the genetically modified tumor cells, an immunostimulatory agent. The invention further provides compositions useful for practicing the claimed methods.
    Type: Grant
    Filed: July 18, 1994
    Date of Patent: June 30, 1998
    Assignee: Sidney Kimmel Cancer Center
    Inventors: Habib Fakhrai, Oliver Dorigo, Robert E. Sobol