Patents by Inventor Oliver Grimm
Oliver Grimm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240078670Abstract: The present disclosure is directed, among other things, to automated systems and methods for analyzing, storing, and/or retrieving information associated with biological objects including lymphocytes. In some embodiments, a shape metric is derived for each detected and segmented lymphocyte and the shape metric is stored along with other relevant data.Type: ApplicationFiled: October 30, 2023Publication date: March 7, 2024Applicant: c/o Ventana Medical systems, Inc.Inventors: Joerg Bredno, Konstanty Korski, Oliver Grimm
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Patent number: 11842483Abstract: According to various embodiments, a system and method for processing an image of a biological specimen stained for a presence of at least one lymphocyte biomarker is disclosed. The system and method are configured to detect lymphocytes in the image and compute a foreground segmentation mask based on the lymphocytes detected within the image. Outlines of the detected lymphocytes are identified in the image by filtering the image with the computed foreground segmentation mask. A shape metric may be derived for each of the detected lymphocytes based on the identified lymphocytes outlines. The derived shape metric may be associated with location information for each of the detected lymphocytes and a value of each of the derived shape metric may be compared to a predetermined threshold value. A predictive cell motility label may be assigned to each of the detected lymphocytes based on the comparison.Type: GrantFiled: October 9, 2020Date of Patent: December 12, 2023Assignee: VENTANA MEDICAL SYSTEMS, INC.Inventors: Joerg Bredno, Konstanty Korski, Oliver Grimm
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Publication number: 20230177691Abstract: Methods of generating a metric to quantitatively represent an effect of a treatment are disclosed. In one arrangement, first and second sample data units are received, each representing a segmented image of a biological sample taken from a subject. The segmentation divides the image into plural segmentation sets of regions. Each of the first and second sample data units is analysed to determine information about a spatial distribution of biomarkers relative to the segmentation sets. A metric is generated using a combination of the determined information about the spatial distribution of biomarkers relative to the segmentation sets for the first and second sample data units.Type: ApplicationFiled: January 17, 2023Publication date: June 8, 2023Applicant: HOFFMANN-LA ROCHE INC.Inventors: Oliver GRIMM, Marta CANAMERO
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Patent number: 11017533Abstract: The system is configured to receive at least one digital image of a tissue sample of a patient; analyze the at least one received image for identifying tumor cells in a region of the at least one received image; analyze the at least one received image for identifying FAP+ areas in the region, each FAP+ area being a pixel blob representing one or more cells express the fibroblast activation protein—“FAP”; analyze the at least one received image for identifying distances between the identified tumor cells and their respective nearest FAP+ area; computing a proximity measure as a function of the identified distances; process the proximity measure by a classifier for generating a classification result, the classification result indicating if the tumor of the patient can be treated by a drug or drug-component that binds to FAP; and output the classification result.Type: GrantFiled: November 2, 2017Date of Patent: May 25, 2021Assignee: HOFFMANN-LA ROCHE INC.Inventors: Fabien Gaire, Oliver Grimm, Hadassah Sumum Sade, Suzana Vega Harring
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Publication number: 20210027462Abstract: The present disclosure is directed, among other things, to automated systems and methods for analyzing, storing, and/or retrieving information associated with biological objects including lymphocytes. In some embodiments, a shape metric is derived for each detected and segmented lymphocyte and the shape metric is stored along with other relevant data.Type: ApplicationFiled: October 9, 2020Publication date: January 28, 2021Inventors: Joerg Bredno, Konstanty Korski, Oliver Grimm
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Patent number: 10500914Abstract: A connecting rod for a multiple connecting rod axle of a motor vehicle, especially a lower wishbone for a multiple connecting rod rear axle, includes a substantially Y-shaped basic framework with a first arm, the free end region of which has a first seat for linking the connecting rod to an auxiliary frame or a vehicle body, with a second arm, the free end region of which has a second seat for linking the connecting rod to the auxiliary frame rod or the vehicle body, and with a third arm, the free end region of which has a third seat for linking the connecting rod to a wheel carrier. The connecting rod is manufactured in one piece with the seats.Type: GrantFiled: January 9, 2018Date of Patent: December 10, 2019Assignee: KSM Castings Group GmbHInventors: Florian Buerger, Christian Richard, Christian Moschner, Klaus Greven, Oliver Grimm, Manikandan Loganathan
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Publication number: 20190287249Abstract: The system is configured to receive at least one digital image of a tissue sample of a patient; analyze the at least one received image for identifying tumor cells in a region of the at least one received image; analyze the at least one received image for identifying FAP+ areas in the region, each FAP+ area being a pixel blob representing one or more cells express the fibroblast activation protein—“FAP”; analyze the at least one received image for identifying distances between the identified tumor cells and their respective nearest FAP+ area; computing a proximity measure as a function of the identified distances; process the proximity measure by a classifier for generating a classification result, the classification result indicating if the tumor of the patient can be treated by a drug or drug-component that binds to FAP; and output the classification result.Type: ApplicationFiled: November 2, 2017Publication date: September 19, 2019Applicant: HOFFMANN-LA ROCHE INC.Inventors: Fabien GAIRE, Oliver GRIMM, Hadassah Sumum SADE, Suzana VEGA HARRING
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Publication number: 20190055628Abstract: The invention relates to an Al casting alloy.Type: ApplicationFiled: February 16, 2017Publication date: February 21, 2019Applicant: KSM CASTINGS GROUP GMBHInventors: Oliver GRIMM, Klaus GREVEN
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Publication number: 20180195609Abstract: A connecting rod for a multiple connecting rod axle of a motor vehicle, especially a lower wishbone for a multiple connecting rod rear axle, includes a substantially Y-shaped basic framework with a first arm, the free end region of which has a first seat for linking the connecting rod to an auxiliary frame or a vehicle body, with a second arm, the free end region of which has a second seat for linking the connecting rod to the auxiliary frame rod or the vehicle body, and with a third arm, the free end region of which has a third seat for linking the connecting rod to a wheel carrier. The connecting rod is manufactured in one piece with the seats.Type: ApplicationFiled: January 9, 2018Publication date: July 12, 2018Applicant: KSM Castings Group GmbHInventors: Florian BUERGER, Christian RICHARD, Christian MOSCHNER, Klaus GREVEN, Oliver GRIMM, Manikandan LOGANATHAN
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Patent number: 9969385Abstract: The invention relates to a method for carrying out a parking process for a vehicle (1), in which the parking process is carried out at least semi-autonomously, a parking assistance device (2) of the vehicle being able to carry out an autonomous parking process or a semi-autonomous parking process and, depending on environmental conditions of the vehicle (1), the parking assistance device (2) deciding whether a parking process is carried out autonomously or semi-autonomously.Type: GrantFiled: August 29, 2012Date of Patent: May 15, 2018Assignee: VALEO Schalter und Sensoren GmbHInventors: Nicolas Jecker, Oliver Grimm
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Patent number: 9797031Abstract: An aluminum casting alloy contains Si: 3.0 wt.-% to 3.8 wt.-% Mg: 0.3 wt.-% to 0.6 wt.-% Cr: 0.25 wt.-% to 0.35 wt.-% Fe: <0.18 wt.-% Mn: <0.06 wt.-% Ti: <0.16 wt.-% Cu: <0.006 wt.-% Sr: 0.010 wt.-% to 0.030 wt.-% Zr: <0.006 wt.-% Zn: <0.006 wt.-% Contaminants: <0.1 wt.-%, and is supplemented to 100 wt.-%, in each instance, with Al.Type: GrantFiled: August 22, 2013Date of Patent: October 24, 2017Assignee: KSM Castings Group GmbHInventors: Klaus Greven, Manikandan Loganathan, Oliver Grimm, Lutz Wolkenstein, Heinrich Hanekop, Stephan Bukowski
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Patent number: 9789904Abstract: The invention relates to a maneuvering system (2) for the automated maneuvering of a motor vehicle (1), including an on-board control device (3) which is designed to provide control signals (S) to a drive device and/or steering device (5) of the motor vehicle (1) and thereby to carry out a maneuvering operation of the motor vehicle (1) automatically, and including a portable communication device (4) which is operable by a user, which is designed to communicate wirelessly with the on-board control device (3) and thereby to enable and/or interrupt the maneuvering operation as a function of an input by the user at an operating device (8) of the portable communication device (4).Type: GrantFiled: April 10, 2013Date of Patent: October 17, 2017Assignee: VALEO Schalter und Sensoren GmbHInventors: Nicolas Jecker, Oliver Grimm, Vsevolod Vovkushevsky
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Patent number: 9656691Abstract: The invention relates to a method for performing an at least semi-autonomous parking process of a motor vehicle (1) in a garage (16), wherein the garage (16) is detected and a current position of the motor vehicle (1) relative to the garage (16) is determined by means of a parking assistance system (2) of the motor vehicle (1), and wherein following detection of the garage (16) the at least semi-autonomous parking process is carried out depending on the current position of the motor vehicle (1) relative to the garage (16), wherein an image of the garage (16) is recorded by means of a camera (8, 10, 11, 12) of the parking assistance system (2) and the detection of the garage (16) comprises subjecting the image to pattern recognition regarding the garage entrance (17) by means of an image processor (6) of the parking assistance system (2) and identifying the garage (16) by means of the pattern recognition.Type: GrantFiled: November 12, 2013Date of Patent: May 23, 2017Assignee: VALEO Schalter und Sensoren GmbHInventors: Markus Heimberger, Vsevolod Vovkushevsky, Oliver Grimm
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Publication number: 20160288833Abstract: The invention relates to a method for performing an at least semi-autonomous parking process of a motor vehicle (1) in a garage (16), wherein the garage (16) is detected and a current position of the motor vehicle (1) relative to the garage (16) is determined by means of a parking assistance system (2) of the motor vehicle (1), and wherein following detection of the garage (16) the at least semi-autonomous parking process is carried out depending on the current position of the motor vehicle (1) relative to the garage (16), wherein an image of the garage (16) is recorded by means of a camera (8, 10, 11, 12) of the parking assistance system (2) and the detection of the garage (16) comprises subjecting the image to pattern recognition regarding the garage entrance (17) by means of an image processor (6) of the parking assistance system (2) and identifying the garage (16) by means of the pattern recognition.Type: ApplicationFiled: November 12, 2013Publication date: October 6, 2016Applicant: VALEO Schalter und Sensoren GmbHInventors: Markus Heimberger, Vsevolod Vovkushevsky, Oliver Grimm
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Patent number: 9415804Abstract: The invention relates to a device and a method for displaying objects in the surroundings of a vehicle having a sensor arrangement, in order to sense objects in the surroundings of the vehicle and to determine the position thereof relative to the vehicle, wherein the sensor arrangement covers, with its detection range, only a partial area of the surroundings of the vehicle; in order to improve the assistance provided to the driver during parking processes and the processes of removing a vehicle from a parking space, the processing device is designed to determine the area of the surroundings of the vehicle for which no object information is yet available, since said area has not yet been passed over by the detection range of the sensor arrangement, and the display device is designed to display the extent of this area.Type: GrantFiled: June 7, 2010Date of Patent: August 16, 2016Assignee: VALEO Schalter und Sensoren GmbHInventors: Nicolas Jecker, Oliver Grimm, Vsevolod Vovkushevsky, Tobias Geiger
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Patent number: 9351498Abstract: The present invention concerns an apparatus and a corresponding method for non-contact identifying of red tissue structures in products of slaughtered animal bodies, comprising a conveying device for continuous conveyance of the products in a conveying direction, a light source configured to generate a flat light field which is designed and adapted to form a light line running transversely to the conveying direction of the product from the flat light field, a detecting device for identifying the red tissue structures, which comprises at least one optical sensor for recording the portions of light reflected by the product, wherein the light source is configured as an infrared light source and the light source is arranged such that the plane of the flat light field relative to the conveying direction is tilted by a light field angle of less than 90°.Type: GrantFiled: January 14, 2014Date of Patent: May 31, 2016Assignee: Nordischer Maschinenbau Rud. Baader GmbH + Co. KGInventors: Oliver Grimm, Björn Rünger, Arne Irmler
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Publication number: 20150342202Abstract: The present invention concerns an apparatus and a corresponding method for non-contact identifying of red tissue structures in products of slaughtered animal bodies, comprising a conveying device for continuous conveyance of the products in a conveying direction, a light source configured to generate a flat light field which is designed and adapted to form a light line running transversely to the conveying direction of the product from the flat light field, a detecting device for identifying the red tissue structures, which comprises at least one optical sensor means for recording the portions of light reflected by the product, wherein the light source is configured as an infrared light source and the light source is arranged such that the plane of the flat light field relative to the conveying direction is tilted by a light field angle of less than 90°.Type: ApplicationFiled: January 14, 2014Publication date: December 3, 2015Inventors: Oliver Grimm, Björn Rünger, Arne Irmler
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Patent number: 9174676Abstract: The invention relates to a method for executing an at least semi-autonomous parking process of a vehicle (13) by means of a parking assistance system (15), in which ambient conditions of the vehicle (13) are sensed as it travels past a potential parking space (3), and a parking path is determined as a function of the ambient conditions and of the parking space (3), wherein the ambient conditions comprise at least one obstacle (18, 18?, 18?) which is external to the parking space and does not directly bound the parking space (3) and is detected as near to the vehicle and is taken into account in the determination of the parking path (3), wherein the parking process is executed in a plurality of maneuvers (26, 27, 29; 34, 38, 39), and at least one maneuver (26, 27, 29; 34, 38, 39) which is executed with an autonomous steering intervention is determined in terms of its profile as a function of the obstacle (18, 18?, 18?). The invention also relates to a parking assistance system (15) for a vehicle (13).Type: GrantFiled: June 7, 2010Date of Patent: November 3, 2015Assignee: VALEO Schalter und Sensoren GmbHInventors: Nicolas Jecker, Oliver Grimm, Tobias Geiger
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Patent number: 9140553Abstract: The invention relates to a method for assisting a driver of a motor vehicle (1) when parking in a parking space (19), in particular in a garage (18), using a driver assistance device (2) of the motor vehicle (1), wherein: in a learning mode of the driver assistance device (2), reference data related to the surrounding area (22) of the parking space (19) are recorded and stored using a sensor device (7) of the driver assistance device (2), while the motor vehicle (1) is parked in the parking space (19) while controlled by the driver, a reference target position (27), which is reached by the motor vehicle (1) in the learning mode, is recorded by the driver assistance device (2) and data with information about this reference target position (27) are stored, in a subsequent operating mode of the driver assistance device (2) different from the learning mode, sensor data are detected by the sensor device (7) and compared with the reference data, wherein depending on this comparison the surrounding area (22) of tType: GrantFiled: May 24, 2011Date of Patent: September 22, 2015Assignee: VALEO Schalter und Sensoren GmbHInventors: Oliver Grimm, Nicolas Jecker
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Publication number: 20150127208Abstract: The invention relates to a manoeuvring system (2) for the automated manoeuvring of a motor vehicle (1), including an on-board control device (3) which is designed to provide control signals (S) to a drive device and/or steering device (5) of the motor vehicle (1) and thereby to carry out a manoeuvring operation of the motor vehicle (1) automatically, and including a portable communication device (4) which is operable by a user, which is designed to communicate wirelessly with the on-board control device (3) and thereby to enable and/or interrupt the manoeuvring operation as a function of an input by the user at an operating device (8) of the portable communication device (4).Type: ApplicationFiled: April 10, 2013Publication date: May 7, 2015Applicant: VALEO Schalter und Sensoren GmbHInventors: Nicolas Jecker, Oliver Grimm, Vsevolod Vovkushevsky