Patents by Inventor Oliver Grimm

Oliver Grimm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240078670
    Abstract: The present disclosure is directed, among other things, to automated systems and methods for analyzing, storing, and/or retrieving information associated with biological objects including lymphocytes. In some embodiments, a shape metric is derived for each detected and segmented lymphocyte and the shape metric is stored along with other relevant data.
    Type: Application
    Filed: October 30, 2023
    Publication date: March 7, 2024
    Applicant: c/o Ventana Medical systems, Inc.
    Inventors: Joerg Bredno, Konstanty Korski, Oliver Grimm
  • Patent number: 11842483
    Abstract: According to various embodiments, a system and method for processing an image of a biological specimen stained for a presence of at least one lymphocyte biomarker is disclosed. The system and method are configured to detect lymphocytes in the image and compute a foreground segmentation mask based on the lymphocytes detected within the image. Outlines of the detected lymphocytes are identified in the image by filtering the image with the computed foreground segmentation mask. A shape metric may be derived for each of the detected lymphocytes based on the identified lymphocytes outlines. The derived shape metric may be associated with location information for each of the detected lymphocytes and a value of each of the derived shape metric may be compared to a predetermined threshold value. A predictive cell motility label may be assigned to each of the detected lymphocytes based on the comparison.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: December 12, 2023
    Assignee: VENTANA MEDICAL SYSTEMS, INC.
    Inventors: Joerg Bredno, Konstanty Korski, Oliver Grimm
  • Publication number: 20230177691
    Abstract: Methods of generating a metric to quantitatively represent an effect of a treatment are disclosed. In one arrangement, first and second sample data units are received, each representing a segmented image of a biological sample taken from a subject. The segmentation divides the image into plural segmentation sets of regions. Each of the first and second sample data units is analysed to determine information about a spatial distribution of biomarkers relative to the segmentation sets. A metric is generated using a combination of the determined information about the spatial distribution of biomarkers relative to the segmentation sets for the first and second sample data units.
    Type: Application
    Filed: January 17, 2023
    Publication date: June 8, 2023
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Oliver GRIMM, Marta CANAMERO
  • Patent number: 11017533
    Abstract: The system is configured to receive at least one digital image of a tissue sample of a patient; analyze the at least one received image for identifying tumor cells in a region of the at least one received image; analyze the at least one received image for identifying FAP+ areas in the region, each FAP+ area being a pixel blob representing one or more cells express the fibroblast activation protein—“FAP”; analyze the at least one received image for identifying distances between the identified tumor cells and their respective nearest FAP+ area; computing a proximity measure as a function of the identified distances; process the proximity measure by a classifier for generating a classification result, the classification result indicating if the tumor of the patient can be treated by a drug or drug-component that binds to FAP; and output the classification result.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: May 25, 2021
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Fabien Gaire, Oliver Grimm, Hadassah Sumum Sade, Suzana Vega Harring
  • Publication number: 20210027462
    Abstract: The present disclosure is directed, among other things, to automated systems and methods for analyzing, storing, and/or retrieving information associated with biological objects including lymphocytes. In some embodiments, a shape metric is derived for each detected and segmented lymphocyte and the shape metric is stored along with other relevant data.
    Type: Application
    Filed: October 9, 2020
    Publication date: January 28, 2021
    Inventors: Joerg Bredno, Konstanty Korski, Oliver Grimm
  • Patent number: 10500914
    Abstract: A connecting rod for a multiple connecting rod axle of a motor vehicle, especially a lower wishbone for a multiple connecting rod rear axle, includes a substantially Y-shaped basic framework with a first arm, the free end region of which has a first seat for linking the connecting rod to an auxiliary frame or a vehicle body, with a second arm, the free end region of which has a second seat for linking the connecting rod to the auxiliary frame rod or the vehicle body, and with a third arm, the free end region of which has a third seat for linking the connecting rod to a wheel carrier. The connecting rod is manufactured in one piece with the seats.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: December 10, 2019
    Assignee: KSM Castings Group GmbH
    Inventors: Florian Buerger, Christian Richard, Christian Moschner, Klaus Greven, Oliver Grimm, Manikandan Loganathan
  • Publication number: 20190287249
    Abstract: The system is configured to receive at least one digital image of a tissue sample of a patient; analyze the at least one received image for identifying tumor cells in a region of the at least one received image; analyze the at least one received image for identifying FAP+ areas in the region, each FAP+ area being a pixel blob representing one or more cells express the fibroblast activation protein—“FAP”; analyze the at least one received image for identifying distances between the identified tumor cells and their respective nearest FAP+ area; computing a proximity measure as a function of the identified distances; process the proximity measure by a classifier for generating a classification result, the classification result indicating if the tumor of the patient can be treated by a drug or drug-component that binds to FAP; and output the classification result.
    Type: Application
    Filed: November 2, 2017
    Publication date: September 19, 2019
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Fabien GAIRE, Oliver GRIMM, Hadassah Sumum SADE, Suzana VEGA HARRING
  • Publication number: 20190055628
    Abstract: The invention relates to an Al casting alloy.
    Type: Application
    Filed: February 16, 2017
    Publication date: February 21, 2019
    Applicant: KSM CASTINGS GROUP GMBH
    Inventors: Oliver GRIMM, Klaus GREVEN
  • Publication number: 20180195609
    Abstract: A connecting rod for a multiple connecting rod axle of a motor vehicle, especially a lower wishbone for a multiple connecting rod rear axle, includes a substantially Y-shaped basic framework with a first arm, the free end region of which has a first seat for linking the connecting rod to an auxiliary frame or a vehicle body, with a second arm, the free end region of which has a second seat for linking the connecting rod to the auxiliary frame rod or the vehicle body, and with a third arm, the free end region of which has a third seat for linking the connecting rod to a wheel carrier. The connecting rod is manufactured in one piece with the seats.
    Type: Application
    Filed: January 9, 2018
    Publication date: July 12, 2018
    Applicant: KSM Castings Group GmbH
    Inventors: Florian BUERGER, Christian RICHARD, Christian MOSCHNER, Klaus GREVEN, Oliver GRIMM, Manikandan LOGANATHAN
  • Patent number: 9969385
    Abstract: The invention relates to a method for carrying out a parking process for a vehicle (1), in which the parking process is carried out at least semi-autonomously, a parking assistance device (2) of the vehicle being able to carry out an autonomous parking process or a semi-autonomous parking process and, depending on environmental conditions of the vehicle (1), the parking assistance device (2) deciding whether a parking process is carried out autonomously or semi-autonomously.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: May 15, 2018
    Assignee: VALEO Schalter und Sensoren GmbH
    Inventors: Nicolas Jecker, Oliver Grimm
  • Patent number: 9797031
    Abstract: An aluminum casting alloy contains Si: 3.0 wt.-% to 3.8 wt.-% Mg: 0.3 wt.-% to 0.6 wt.-% Cr: 0.25 wt.-% to 0.35 wt.-% Fe: <0.18 wt.-% Mn: <0.06 wt.-% Ti: <0.16 wt.-% Cu: <0.006 wt.-% Sr: 0.010 wt.-% to 0.030 wt.-% Zr: <0.006 wt.-% Zn: <0.006 wt.-% Contaminants: <0.1 wt.-%, and is supplemented to 100 wt.-%, in each instance, with Al.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: October 24, 2017
    Assignee: KSM Castings Group GmbH
    Inventors: Klaus Greven, Manikandan Loganathan, Oliver Grimm, Lutz Wolkenstein, Heinrich Hanekop, Stephan Bukowski
  • Patent number: 9789904
    Abstract: The invention relates to a maneuvering system (2) for the automated maneuvering of a motor vehicle (1), including an on-board control device (3) which is designed to provide control signals (S) to a drive device and/or steering device (5) of the motor vehicle (1) and thereby to carry out a maneuvering operation of the motor vehicle (1) automatically, and including a portable communication device (4) which is operable by a user, which is designed to communicate wirelessly with the on-board control device (3) and thereby to enable and/or interrupt the maneuvering operation as a function of an input by the user at an operating device (8) of the portable communication device (4).
    Type: Grant
    Filed: April 10, 2013
    Date of Patent: October 17, 2017
    Assignee: VALEO Schalter und Sensoren GmbH
    Inventors: Nicolas Jecker, Oliver Grimm, Vsevolod Vovkushevsky
  • Patent number: 9656691
    Abstract: The invention relates to a method for performing an at least semi-autonomous parking process of a motor vehicle (1) in a garage (16), wherein the garage (16) is detected and a current position of the motor vehicle (1) relative to the garage (16) is determined by means of a parking assistance system (2) of the motor vehicle (1), and wherein following detection of the garage (16) the at least semi-autonomous parking process is carried out depending on the current position of the motor vehicle (1) relative to the garage (16), wherein an image of the garage (16) is recorded by means of a camera (8, 10, 11, 12) of the parking assistance system (2) and the detection of the garage (16) comprises subjecting the image to pattern recognition regarding the garage entrance (17) by means of an image processor (6) of the parking assistance system (2) and identifying the garage (16) by means of the pattern recognition.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: May 23, 2017
    Assignee: VALEO Schalter und Sensoren GmbH
    Inventors: Markus Heimberger, Vsevolod Vovkushevsky, Oliver Grimm
  • Publication number: 20160288833
    Abstract: The invention relates to a method for performing an at least semi-autonomous parking process of a motor vehicle (1) in a garage (16), wherein the garage (16) is detected and a current position of the motor vehicle (1) relative to the garage (16) is determined by means of a parking assistance system (2) of the motor vehicle (1), and wherein following detection of the garage (16) the at least semi-autonomous parking process is carried out depending on the current position of the motor vehicle (1) relative to the garage (16), wherein an image of the garage (16) is recorded by means of a camera (8, 10, 11, 12) of the parking assistance system (2) and the detection of the garage (16) comprises subjecting the image to pattern recognition regarding the garage entrance (17) by means of an image processor (6) of the parking assistance system (2) and identifying the garage (16) by means of the pattern recognition.
    Type: Application
    Filed: November 12, 2013
    Publication date: October 6, 2016
    Applicant: VALEO Schalter und Sensoren GmbH
    Inventors: Markus Heimberger, Vsevolod Vovkushevsky, Oliver Grimm
  • Patent number: 9415804
    Abstract: The invention relates to a device and a method for displaying objects in the surroundings of a vehicle having a sensor arrangement, in order to sense objects in the surroundings of the vehicle and to determine the position thereof relative to the vehicle, wherein the sensor arrangement covers, with its detection range, only a partial area of the surroundings of the vehicle; in order to improve the assistance provided to the driver during parking processes and the processes of removing a vehicle from a parking space, the processing device is designed to determine the area of the surroundings of the vehicle for which no object information is yet available, since said area has not yet been passed over by the detection range of the sensor arrangement, and the display device is designed to display the extent of this area.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: August 16, 2016
    Assignee: VALEO Schalter und Sensoren GmbH
    Inventors: Nicolas Jecker, Oliver Grimm, Vsevolod Vovkushevsky, Tobias Geiger
  • Patent number: 9351498
    Abstract: The present invention concerns an apparatus and a corresponding method for non-contact identifying of red tissue structures in products of slaughtered animal bodies, comprising a conveying device for continuous conveyance of the products in a conveying direction, a light source configured to generate a flat light field which is designed and adapted to form a light line running transversely to the conveying direction of the product from the flat light field, a detecting device for identifying the red tissue structures, which comprises at least one optical sensor for recording the portions of light reflected by the product, wherein the light source is configured as an infrared light source and the light source is arranged such that the plane of the flat light field relative to the conveying direction is tilted by a light field angle of less than 90°.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: May 31, 2016
    Assignee: Nordischer Maschinenbau Rud. Baader GmbH + Co. KG
    Inventors: Oliver Grimm, Björn Rünger, Arne Irmler
  • Publication number: 20150342202
    Abstract: The present invention concerns an apparatus and a corresponding method for non-contact identifying of red tissue structures in products of slaughtered animal bodies, comprising a conveying device for continuous conveyance of the products in a conveying direction, a light source configured to generate a flat light field which is designed and adapted to form a light line running transversely to the conveying direction of the product from the flat light field, a detecting device for identifying the red tissue structures, which comprises at least one optical sensor means for recording the portions of light reflected by the product, wherein the light source is configured as an infrared light source and the light source is arranged such that the plane of the flat light field relative to the conveying direction is tilted by a light field angle of less than 90°.
    Type: Application
    Filed: January 14, 2014
    Publication date: December 3, 2015
    Inventors: Oliver Grimm, Björn Rünger, Arne Irmler
  • Patent number: 9174676
    Abstract: The invention relates to a method for executing an at least semi-autonomous parking process of a vehicle (13) by means of a parking assistance system (15), in which ambient conditions of the vehicle (13) are sensed as it travels past a potential parking space (3), and a parking path is determined as a function of the ambient conditions and of the parking space (3), wherein the ambient conditions comprise at least one obstacle (18, 18?, 18?) which is external to the parking space and does not directly bound the parking space (3) and is detected as near to the vehicle and is taken into account in the determination of the parking path (3), wherein the parking process is executed in a plurality of maneuvers (26, 27, 29; 34, 38, 39), and at least one maneuver (26, 27, 29; 34, 38, 39) which is executed with an autonomous steering intervention is determined in terms of its profile as a function of the obstacle (18, 18?, 18?). The invention also relates to a parking assistance system (15) for a vehicle (13).
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: November 3, 2015
    Assignee: VALEO Schalter und Sensoren GmbH
    Inventors: Nicolas Jecker, Oliver Grimm, Tobias Geiger
  • Patent number: 9140553
    Abstract: The invention relates to a method for assisting a driver of a motor vehicle (1) when parking in a parking space (19), in particular in a garage (18), using a driver assistance device (2) of the motor vehicle (1), wherein: in a learning mode of the driver assistance device (2), reference data related to the surrounding area (22) of the parking space (19) are recorded and stored using a sensor device (7) of the driver assistance device (2), while the motor vehicle (1) is parked in the parking space (19) while controlled by the driver, a reference target position (27), which is reached by the motor vehicle (1) in the learning mode, is recorded by the driver assistance device (2) and data with information about this reference target position (27) are stored, in a subsequent operating mode of the driver assistance device (2) different from the learning mode, sensor data are detected by the sensor device (7) and compared with the reference data, wherein depending on this comparison the surrounding area (22) of t
    Type: Grant
    Filed: May 24, 2011
    Date of Patent: September 22, 2015
    Assignee: VALEO Schalter und Sensoren GmbH
    Inventors: Oliver Grimm, Nicolas Jecker
  • Publication number: 20150127208
    Abstract: The invention relates to a manoeuvring system (2) for the automated manoeuvring of a motor vehicle (1), including an on-board control device (3) which is designed to provide control signals (S) to a drive device and/or steering device (5) of the motor vehicle (1) and thereby to carry out a manoeuvring operation of the motor vehicle (1) automatically, and including a portable communication device (4) which is operable by a user, which is designed to communicate wirelessly with the on-board control device (3) and thereby to enable and/or interrupt the manoeuvring operation as a function of an input by the user at an operating device (8) of the portable communication device (4).
    Type: Application
    Filed: April 10, 2013
    Publication date: May 7, 2015
    Applicant: VALEO Schalter und Sensoren GmbH
    Inventors: Nicolas Jecker, Oliver Grimm, Vsevolod Vovkushevsky