Patents by Inventor Oliver J. Ratcliffe
Oliver J. Ratcliffe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240124885Abstract: The present disclosure identifies new genes which have the potential to increase broad acre yield in crops. This disclosure is based upon our fundamental knowledge of light signal transduction and our understanding of the roles these genes play in regulating plant growth and development in response to light. Transgenic plants with gain- or loss-of-function of one of these genes, or in combination, are expected to show significant improvements in broad acre yield and stress tolerance.Type: ApplicationFiled: September 12, 2023Publication date: April 18, 2024Inventors: Rajnish Khanna, Brent A. Kronmiller, Oliver J. Ratcliffe, T. Lynne Reuber, Marie E. Petracek, Robert J. Meister, Sasha Preuss, Amanda McClerren, Qungang Qi
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Publication number: 20240093219Abstract: Polynucleotides incorporated into nucleic acid constructs have been introduced into plants and were ectopically expressed. The encoded polypeptides of the invention have been shown to confer at least one regulatory activity and confer earlier flowering, longer floral organ retention, increased cold tolerance, greater tolerance to water deprivation, altered carbon-nitrogen balance sensing, increased low nitrogen tolerance, and/or increased tolerance to hyperosmotic stress as compared to a control plant.Type: ApplicationFiled: September 6, 2023Publication date: March 21, 2024Inventors: Jose Luis Riechmann, Oliver J. Ratcliffe, T. Lynne Reuber, Katherine Krolikowski, Jacqueline E. Heard, Omaira Pineda, Cai-Zhong Jiang, Robert A. Creelman, Roderick W. Kumimoto, Paul S. Chomet
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Publication number: 20220220492Abstract: Polynucleotides incorporated into nucleic acid constructs have been introduced into plants and were ectopically expressed. The encoded polypeptides of the invention have been shown to confer at least one regulatory activity and confer earlier flowering, longer floral organ retention, increased cold tolerance, greater tolerance to water deprivation, altered carbon-nitrogen balance sensing, increased low nitrogen tolerance, and/or increased tolerance to hyperosmotic stress as compared to a control plant.Type: ApplicationFiled: September 1, 2020Publication date: July 14, 2022Inventors: Jose Luis Riechmann, Oliver J. Ratcliffe, T. Lynne Reuber, Katherine Krolikowski, Jacqueline E. Heard, Omaira Pineda, Cai-Zhong Jiang, Robert A. Creelman, Roderick W. Kumimoto, Paul S. Chomet
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Publication number: 20220042029Abstract: The present disclosure identifies new genes which have the potential to increase broad acre yield in crops. This disclosure is based upon our fundamental knowledge of light signal transduction and our understanding of tile roles these genes play in regulating plant growth and development in response to light. Transgenic plants with gain- or loss-of-function of one of these genes, or in combination, are expected to show significant improvements in broad acre yield and stress tolerance.Type: ApplicationFiled: August 17, 2021Publication date: February 10, 2022Inventors: Rajnish Khanna, Brent A. Kronmiller, Oliver J. Ratcliffe, T. Lynne Reuber, Marie E. Petracek, Robert J. Meister, Sasha Preuss, Amanda McClerren, Qungang Qi
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Patent number: 10982218Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.Type: GrantFiled: November 20, 2018Date of Patent: April 20, 2021Assignee: Mendel Biotechnology, Inc.Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
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Publication number: 20210054397Abstract: Polynucleotides and polypeptides incorporated into expression vectors have been introduced into plants and were ectopically expressed. The polypeptides of the invention have been shown to confer at least one regulatory activity and confer increased yield, greater height, greater early season growth, greater canopy coverage, greater stem diameter, greater late season vigor, increased secondary rooting, more rapid germination, greater cold tolerance, greater tolerance to water deprivation, reduced stomatal conductance, altered C/N sensing, increased low nitrogen tolerance, increased low phosphorus tolerance, or increased tolerance to hyperosmotic stress as compared to the control plant as compared to a control plant.Type: ApplicationFiled: September 8, 2020Publication date: February 25, 2021Inventors: Robert A. Creelman, Neal I. Gutterson, Oliver J. Ratcliffe, T. Lynne Reuber, Richard Eric Cerny, Kimberly Faye Zobrist Duff, Susanne Kjemtrup-Lovelace, Robert J. Meister, Marie E. Petracek, Thomas Ruff, Qingzhang Xu
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Patent number: 10815493Abstract: Polynucleotides incorporated into nucleic acid constructs have been introduced into plants and were ectopically expressed. The encoded polypeptides of the invention have been shown to confer at least one regulatory activity and confer earlier flowering, longer floral organ retention, increased cold tolerance, greater tolerance to water deprivation, altered carbon-nitrogen balance sensing, increased low nitrogen tolerance, and/or increased tolerance to hyperosmotic stress as compared to a control plant.Type: GrantFiled: February 7, 2019Date of Patent: October 27, 2020Assignees: Mendel Biotechnology, Inc., Monsanto Technology LLCInventors: Jose Luis Riechmann, Oliver J. Ratcliffe, T. Lynne Reuber, Katherine Krolikowski, Jacqueline E. Heard, Omaira Pineda, Cai-Zhong Jiang, Robert A. Creelman, Roderick W. Kumimoto, Paul S. Chomet
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Patent number: 10787677Abstract: Polynucleotides and polypeptides incorporated into expression vectors have been introduced into plants and were ectopically expressed. The polypeptides of the invention have been shown to confer at least one regulatory activity and confer increased yield, greater height, greater early season growth, greater canopy coverage, greater stem diameter, greater late season vigor, increased secondary rooting, more rapid germination, greater cold tolerance, greater tolerance to water deprivation, reduced stomatal conductance, altered C/N sensing, increased low nitrogen tolerance, increased low phosphorus tolerance, or increased tolerance to hyperosmotic stress as compared to the control plant as compared to a control plant.Type: GrantFiled: May 7, 2018Date of Patent: September 29, 2020Assignees: Mendel Biotechnology, Inc., Monsanto Technology LLCInventors: Robert A. Creelman, Neal I. Gutterson, Oliver J. Ratcliffe, T. Lynne Reuber, Richard Eric Cerny, Kimberly Faye Zobrist Duff, Susanne Kjemtrup-Lovelace, Robert J. Meister, Marie E. Petracek, Thomas Ruff, Qingzhang Xu
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Publication number: 20200010844Abstract: The application describes producing polynucleotide variants of the AtHB 17 clade members and introducing the mutant variants into plants to improve plant traits. The mutant polynucleotides encode polypeptides that comprise mutations in the EAR motifs.Type: ApplicationFiled: July 16, 2019Publication date: January 9, 2020Inventors: Robert A. Creelman, Marjorie R. Lundgren, Suqin Cai, Hans E. Holtan, Graham J. Hymus, Oliver J. Ratcliffe, T. Lynne Reuber, Amanda J. Burek, Shiv B. Tiwari, Luc J. Adam, Colleen M. Marion, Megan Lau, Bonnie R. Brayton, Yu Shen
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Publication number: 20190367565Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.Type: ApplicationFiled: April 23, 2019Publication date: December 5, 2019Inventors: Jacqueline E. Heard, Jose Luis Riechmann, Robert A. Creelman, Oliver J. Ratcliffe, Roger D. Canales, Peter P. Repetti, Roderick W. Kumimoto, Neal I. Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S. Century, Luc Adam, James Z Zhang, Frederick D. Hempel, Jeffrey M. Libby
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Publication number: 20190338303Abstract: Polynucleotides and polypeptides incorporated into expression vectors are introduced into plants and were ectopically expressed. These polypeptides may confer at least one regulatory activity and increased yield, increased resource use efficiency, increased water use efficiency, increased light use efficiency, increased photosynthetic capacity, increased photosynthetic rate, increased photosynthetic resource use efficiency, greater vigor, and/or greater biomass as compared to a control plant.Type: ApplicationFiled: July 3, 2019Publication date: November 7, 2019Inventors: Graham J. Hymus, T. Lynne Reuber, Colleen M. Marion, Oliver J. Ratcliffe, Jeffrey M. Libby
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Patent number: 10407689Abstract: The application describes producing polynucleotide variants of the AtHB 17 clade members and introducing the mutant variants into plants to improve plant traits. The mutant polynucleotides encode polypeptides that comprise mutations in the EAR motifs.Type: GrantFiled: August 7, 2017Date of Patent: September 10, 2019Assignee: Mendel Biotechnology, Inc.Inventors: Robert A. Creelman, Marjorie R. Lundgren, Suqin Cai, Hans E. Holtan, Graham J. Hymus, Oliver J. Ratcliffe, T. Lynne Reuber, Amanda J. Burek, Shiv B. Tiwari, Luc J. Adam, Colleen M. Marion, Megan Lau, Bonnie R. Brayton, Yu Shen
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Patent number: 10385356Abstract: This disclosure provides transgenic plants, including crop plants and methods for their production. The transgenic plants comprise recombinant DNA constructs for the expression of polypeptides encoded by the DNA constructs. The polypeptides are capable of conferring improved traits to the transgenic plants when expressed under the control of a tissue-enhanced promoter. This disclosure also pertains to transgenic plants and their progeny plants, wherein the transgenic or progeny plants comprise the recombinant DNA constructs and are selected for having enhanced nitrogen use efficiency and/or nitrogen uptake. Seed of the transgenic plants that can be grown into a plant that comprise the disclosed recombinant DNA constructs and exhibits having enhanced nitrogen use efficiency, and which may be selected for this trait, are also envisioned.Type: GrantFiled: November 13, 2018Date of Patent: August 20, 2019Assignee: KOCH BIOLOGICAL SOLUTIONS, LLCInventors: Robert A. Creelman, Suqin Cai, Hans E. Holtan, T. Lynne Reuber, Oliver J. Ratcliffe
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Publication number: 20190233833Abstract: Polynucleotides incorporated into nucleic acid constructs have been introduced into plants and were ectopically expressed. The encoded polypeptides of the invention have been shown to confer at least one regulatory activity and confer earlier flowering, longer floral organ retention, increased cold tolerance, greater tolerance to water deprivation, altered carbon-nitrogen balance sensing, increased low nitrogen tolerance, and/or increased tolerance to hyperosmotic stress as compared to a control plant.Type: ApplicationFiled: February 7, 2019Publication date: August 1, 2019Inventors: Jose Luis Riechmann, Oliver J. Ratcliffe, T. Lynne Reuber, Katherine Krolikowski, Jacqueline E. Heard, Omaira Pineda, Cai-Zhong Jiang, Robert A. Creelman, Roderick W. Kumimoto, Paul S. Chomet
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Patent number: 10344294Abstract: Polynucleotides and polypeptides incorporated into expression vectors are introduced into plants and were ectopically expressed. These polypeptides may confer at least one regulatory activity and increased yield, increased resource use efficiency, increased water use efficiency, increased light use efficiency, increased photosynthetic capacity, increased photosynthetic rate, increased photosynthetic resource use efficiency, greater vigor, and/or greater biomass as compared to a control plant.Type: GrantFiled: September 17, 2018Date of Patent: July 9, 2019Assignee: Koch Biological Solutions, LLCInventors: Graham J. Hymus, T. Lynne Reuber, Colleen M. Marion, Oliver J. Ratcliffe, Jeffrey M. Libby
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Publication number: 20190194682Abstract: Polynucleotides and polypeptides incorporated into expression vectors are introduced into plants and were ectopically expressed. These polypeptides may confer at least one regulatory activity and increased yield, increased light use efficiency, increased photosynthetic capacity, increased photosynthetic rate, increased photosynthetic resource use efficiency, greater vigor, and/or greater biomass as compared to a control plant.Type: ApplicationFiled: March 12, 2019Publication date: June 27, 2019Inventors: Graham J. Hymus, T. Lynne Reuber, Colleen M. Marion, Oliver J. Ratcliffe, Jeffrey M. Libby
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Patent number: 10316325Abstract: This disclosure provides transgenic plants, including crop plants and methods for their production. The transgenic plants comprise recombinant DNA constructs for the expression of polypeptides encoded by the DNA constructs. The polypeptides are capable of conferring improved traits to the transgenic plants when expressed under the control of a tissue-enhanced promoter. This disclosure also pertains to transgenic plants and their progeny plants, wherein the transgenic or progeny plants comprise the recombinant DNA constructs and are selected for having enhanced nitrogen use efficiency and/or nitrogen uptake. Seed of the transgenic plants that can be grown into a plant that comprise the disclosed recombinant DNA constructs and exhibits having enhanced nitrogen use efficiency, and which may be selected for this trait, are also envisioned.Type: GrantFiled: March 11, 2015Date of Patent: June 11, 2019Assignee: Koch Biological Solutions, LLCInventors: Robert A. Creelman, Suqin Cai, Hans E. Holtan, T. Lynne Reuber, Oliver J. Ratcliffe
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Publication number: 20190153457Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.Type: ApplicationFiled: November 20, 2018Publication date: May 23, 2019Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
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Publication number: 20190127749Abstract: Polynucleotides and polypeptides incorporated into expression vectors are introduced into plants and were ectopically expressed. These polypeptides may confer at least one regulatory activity and increased yield, increased resource use efficiency, increased water use efficiency, increased light use efficiency, increased photosynthetic capacity, increased photosynthetic rate, increased photosynthetic resource use efficiency, greater vigor, and/or greater biomass as compared to a control plant.Type: ApplicationFiled: September 17, 2018Publication date: May 2, 2019Inventors: Graham J. Hymus, T. Lynne Reuber, Colleen M. Marion, Oliver J. Ratcliffe, Jeffrey M. Libby
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Patent number: 10273497Abstract: Polynucleotides incorporated into nucleic acid constructs have been introduced into plants and were ectopically expressed. The encoded polypeptides of the invention have been shown to confer at least one regulatory activity and confer earlier flowering, longer floral organ retention, increased cold tolerance, greater tolerance to water deprivation, altered carbon-nitrogen balance sensing, increased low nitrogen tolerance, and/or increased tolerance to hyperosmotic stress as compared to a control plant.Type: GrantFiled: September 22, 2017Date of Patent: April 30, 2019Assignees: Mendel Biotechnology, Inc., Monsanto Technology LLCInventors: Jose Luis Riechmann, Oliver J. Ratcliffe, T. Lynne Reuber, Katherine Krolikowski, Jacqueline E. Heard, Omaira Pineda, Cai-Zhong Jiang, Robert A. Creelman, Roderick W. Kumimoto, Paul S. Chomet