Patents by Inventor Oliver Kerscher

Oliver Kerscher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR VISUALIZING SUMO
    Publication number: 20220235105
    Abstract: The present disclosure describes pan-SUMO trapping proteins and fusion proteins comprising the pan-SUMO trapping proteins that are stable and bind SUMO-modified proteins with high avidity. The proteins described herein can be used to detect the localization of SUMO-modified proteins cells. The proteins described herein can be used to identify biomarkers for diseases associated with oxidative stress. They can also be used to diagnose and monitor diseases associated with genotoxic and/or proteotoxic stress conditions.
    Type: Application
    Filed: April 4, 2022
    Publication date: July 28, 2022
    Applicant: College of William & Mary
    Inventors: Oliver Kerscher, Rui Yin
  • METHODS AND COMPOSITIONS FOR VISUALIZING SUMO
    Publication number: 20200231641
    Abstract: The present disclosure describes pan-SUMO trapping proteins and fusion proteins comprising the pan-SUMO trapping proteins that are stable and bind SUMO-modified proteins with high avidity. The proteins described herein can be used to detect the localization of SUMO-modified proteins cells. The proteins described herein can be used to identify biomarkers for diseases associated with oxidative stress. They can also be used to diagnose and monitor diseases associated with genotoxic and/or proteotoxic stress conditions.
    Type: Application
    Filed: January 16, 2020
    Publication date: July 23, 2020
    Applicant: College of William & Mary
    Inventors: Oliver Kerscher, Rui Yin
  • SUMO-SPECIFIC AFFINITY TAG
    Publication number: 20130017554
    Abstract: A new SUMO-specific affinity tag is described herein, based on the amino acid sequence from 403-621 of the SUMO protease Ulp1, and containing a crucial substitution of serine for cysteine. This affinity tag is particularly useful for a range of applications, including detection and affinity purification of sumoylated proteins from cell extracts.
    Type: Application
    Filed: June 22, 2012
    Publication date: January 17, 2013
    Applicant: COLLEGE OF WILLIAM AND MARY
    Inventors: Oliver Kerscher, Megan Donaher, Zachary C. Elmore