Abstract: A computer-implemented method is for providing radiomics-related information. In an embodiment, the computer-implemented method includes receiving radiomics-related data; determining, based on the radiomics-related data and an assistance algorithm, a function for processing the radiomics-related data; calculating, based on the radiomics-related data and the function for processing the radiomics-related data, the radiomics-related information; and providing the radiomics-related information.

Abstract: Disclosed is a process for the production of synthesis gas by plasma gasification of solid and/or liquid carbon-containing or hydrocarbon-containing material comprising the steps: (i) providing a solid and/or liquid feedstock comprising particulate carbon- or hydrocarbon-containing material or a mixture of both, (ii) providing a carrier gas and combining this with the solid or liquid feedstock, (iii) feeding said solid or liquid feedstock and said carrier gas as a feed stream into a reactor comprising a reaction chamber or into a vaporizer which is arranged upstream to said reactor, (iv) introducing a swirl gas into the reactor which swirls around the feed stream and covers the interior walls of the reactor, (v) treating said feed stream downstream the introduction of the swirl gas into the reactor with a hot plasma to generate a product stream comprising synthesis gas from said carbon- or hydrocarbon-containing material in the reaction chamber, (vi) removing the product stream from the reaction chamber, and

Abstract: A method for sequencing nucleic acid molecules a) amplifies nucleic acid molecules and b) sequences the amplified nucleic acid molecules. Steps (a) and (b) are carried out on an array of field effect transistor (FET) sensor elements, comprising an array of nanowires. Within the array, each FET may include at least one nanowire, or one each FETs can lie between two nanowires, or one nanowire of a nanowire pair is a nanowire FET, with nucleic acids bound to a nanowire surface. A chip includes one or more arrays of field effect transistor sensor elements. A kit for sequencing nucleic acid molecules, may include one or more amplifying reagents or sequencing reagents.

Abstract: A method for producing a radioactively marked peptide, uses a precursor molecule that is prepared in an organic solvent. A radioactively marked compound having a carboxyl function is added. The carboxyl function is activated, and the activated radioactively marked compound is bonded to the precursor molecule in order to form the radioactively marked peptide. The radioactively marked compound is an isocyanocarboxylic acid. A radioactively marked isocyanocarboxylic acid is used for producing a radioactively marked peptide.

Abstract: A method produces a radioactively marked carboxylate, at least one precursor molecule of the carboxylate being prepared in a solvent including a conductive salt. Radioactively marked carbon dioxide is fed into the solvent. The precursor molecule is electrochemically reacted with the radioactively marked carbon dioxide to form the radioactively marked carboxylate. The radioactively marked carbon dioxide is completely dissolved in the solvent when the precursor molecule is reacted. The radioactively marked carbon dioxide is used for electrochemically synthesizing a radioactively marked carboxylate, the carbon dioxide being completely dissolved in a solvent during synthesis. A microstructure is used for electrochemically synthesizing the radioactively marked carboxylate, radioactively marked carbon dioxide being reacted.

Abstract: A therapeutically active ingredient is administered to the human or animal body. The active ingredient contains an ?-hydroxy acid, an ?-amino acid, a peptide or a protein, the component being radiolabeled with 11C and the radioactive atom replacing the C atom of the carboxyl group or of a peptide bond in the a position. The labeled therapeutically active ingredient which is chemically identical to the active ingredient to be used for therapeutic purposes can be advantageously used in tests which allow a dispersion of the active ingredient to be tested in tissue samples or in the human or animal body by positron emission tomography. The complementary information can for example help to accelerate the approval procedure for medicaments.

Abstract: A method produces a radiopharmaceutical. In the method, an H—Li exchange is made by adding an alkyllithium to an isocyanide, wherein the ?-H atom of the isocyanide is replaced with an Li atom. 11CO2 is added and bonded to the ?-C atom of the isocyanide. By a two-stage hydrolysis, the Li atom is replaced with an H atom and an amino group is formed from the isocyanide group, for example, by adding NH4Cl and HI. The reaction is continuously performed in particular in a microfluidic structure so that reaction times of less than 300 seconds can be achieved for the partial steps. Because the produced radiopharmaceutical has only a low half-life, the short production time has a positive effect on the yield of radioactive pharmaceutical.

Abstract: A microfluidic reactor has a reaction chamber which is configured as an annular channel. It is provided that segments have been formed in the annular channel such that a sequence of inlets and outlets (allows an alternation between the process fluids (A and B) to take place. Furthermore, particles which circulate in the annular channel and can be used, for example, for the adsorption and desorption of ions may be provided in the annular channel. In this way, the ions concerned can, for example, be extracted from the process fluid (A) and transferred into the process fluid (B). In a method, the reactor can be used for example for the purpose of obtaining 18F? ions from water enriched therewith and feeding them to a solvent such as acetonitrile. In the further course of the method, the 18F? ions can be used for producing a radiopharmaceutical (for example FDG).

Abstract: The invention involves a micro-fluidic separation device for liquid mixtures with different boiling points. According to the invention it is intended that a head and a sump are formed in a separating channel; further intended is a thermo unit along the entire length of the separating channel consisting preferably of individually controllable heating and/or cooling elements. This makes it advantageously possible to perform a rectification of the liquid mixture with the separating device where individual fractions of the liquid mixture may be removed via the outlets. This allows continuous operations of the separating device at a simultaneously high degree of efficiency of the separation.