Abstract: A blood circulation assist system comprising an inflow cannula having a lumen and an insertion device configured to be received therein and to facilitate insertion of a portion of the inflow cannula into a heart chamber. The insertion device includes a shaft having distal and proximal end portions and a plurality of lumens. A first lumen is configured to receive a guidewire and a second lumen is configured to receive a pressurized fluid. A tip connected to the distal end portion of the shaft is configured for insertion into the heart chamber. The tip has a hollow interior communicating with the first shaft lumen. An inflatable member is coupled to the distal end portion of the shaft and includes a hollow interior in fluid communication with the second shaft lumen. The inflatable member is movable between deflated and inflated configurations for releasably securing the insertion device to the inflow cannula.

Abstract: A cannula for moving fluids between a pump and the circulatory system of a patient. The cannula includes a liner having an intermediate portion between a proximal portion and a distal portion, and a lumen extending between the proximal and distal portions. At least the intermediate portion of the liner is constructed from a tissue in-growth material for supporting the growth of endothelial cells. A jacket surrounds at least part of the liner.

Abstract: Devices, systems and methods for establishing a blood flow conduit between a chamber in a heart of a patient and a remote location. A blood inflow cannula having an outer surface and proximal and distal end portions. The distal end portion is configured for insertion into the chamber of the heart. First and second anchor elements have respective maximum width dimensions extending outwardly from the outer surface of the cannula. The first anchor element is positioned more distally than the second anchor element defining a tissue receiving space therebetween. The maximum width dimension of the first anchor element may be larger than the maximum width dimension of the second anchor element in use. The first anchor element is configured to be positioned inside the heart chamber and the second anchor element is configured to be positioned outside the heart chamber with heart tissue held in the tissue receiving space therebetween.

Abstract: A blood circulation assist system comprising an inflow cannula having a lumen and an insertion device configured to be received therein and to facilitate insertion of a portion of the inflow cannula into a heart chamber. The insertion device includes a shaft having distal and proximal end portions and a plurality of lumens. A first lumen is configured to receive a guidewire and a second lumen is configured to receive a pressurized fluid. A tip connected to the distal end portion of the shaft is configured for insertion into the heart chamber. The tip has a hollow interior communicating with the first shaft lumen. An inflatable member is coupled to the distal end portion of the shaft and includes a hollow interior in fluid communication with the second shaft lumen. The inflatable member is movable between deflated and inflated configurations for releasably securing the insertion device to the inflow cannula.

Abstract: The invention relates to a blood pump made of titanium with a measuring device for determining flow based on acoustic flow measurement methods, and a blood pump with a temperature sensor and/or a pressure sensor, and a system with a blood pump and an inlet cannula and/or an outlet connector and a method for producing a blood pump with a measuring device.

Abstract: Devices, systems and methods for establishing a blood flow conduit between a chamber in a heart of a patient and a remote location. A blood inflow cannula having an outer surface and proximal and distal end portions. The distal end portion is configured for insertion into the chamber of the heart. First and second anchor elements have respective maximum width dimensions extending outwardly from the outer surface of the cannula. The first anchor element is positioned more distally than the second anchor element defining a tissue receiving space therebetween. The maximum width dimension of the first anchor element may be larger than the maximum width dimension of the second anchor element in use. The first anchor element is configured to be positioned inside the heart chamber and the second anchor element is configured to be positioned outside the heart chamber with heart tissue held in the tissue receiving space therebetween.

Abstract: A blood circulation assist system comprising an inflow cannula having a lumen and an insertion device configured to be received therein and to facilitate insertion of a portion of the inflow cannula into a heart chamber. The insertion device includes a shaft having distal and proximal end portions and a plurality of lumens. A first lumen is configured to receive a guidewire and a second lumen is configured to receive a pressurized fluid. A tip connected to the distal end portion of the shaft is configured for insertion into the heart chamber. The tip has a hollow interior communicating with the first shaft lumen. An inflatable member is coupled to the distal end portion of the shaft and includes a hollow interior in fluid communication with the second shaft lumen. The inflatable member is movable between deflated and inflated configurations for releasably securing the insertion device to the inflow cannula.

Abstract: A cannula for moving fluids between a pump and the circulatory system of a patient. The cannula includes a liner having an intermediate portion between a proximal portion and a distal portion, and a lumen extending between the proximal and distal portions. At least the intermediate portion of the liner is constructed from a tissue in-growth material for supporting the growth of endothelial cells. A jacket surrounds at least part of the liner.

Abstract: A fluid flow system for a patient comprises a controller and an implantable pump assembly. The controller comprises a processing unit and a battery. The processing unit includes a signal generator and one or more pump operational parameters. The signal generator provides a drive signal. The battery provides power to the processing unit. The implantable pump assembly receives the drive signal from the processing unit and propels fluid based on the drive signal. The system includes a local communication device and a remote communication device that each include a unique identifier produced by a security key generator. The remote communication device includes a code generator that produces encrypted commands. The local communication device receives the encrypted commands and modifies a pump operational parameter of the processing unit based on the received encrypted command.

Abstract: The invention relates to a blood pump made of titanium with a measuring device for determining flow based on acoustic flow measurement methods and a blood pump with a temperature sensor and/or a pressure sensor, and a system with a blood pump and an inlet cannula and/or an outlet connector and a method for producing a blood pump with a measuring device.

Abstract: A cannula for insertion through a biologic tissue. The cannula includes a shaft having proximal and distal end portions with a lumen therebetween. The cannula further includes a tip having a proximal end portion, a distal tip end, and a lumen therebetween. The proximal end portion of the tip is secured to the distal end portion of the shaft so that the lumen of the tip is in fluid communication with the lumen of the shaft. The tip includes an opening that extends proximally relative to the distal tip end to permit the flow of fluid into the lumen of the tip even in the event that the distal tip end becomes obstructed.

Abstract: A cannula for implantation into a chamber of a heart includes an elongate body having a lumen extending along a longitudinal axis, a first end, and a second end. The first and second ends define openings into the lumen and the second end includes a flat portion. A flared tip portion extends from the flat portion of the second end in a direction toward the first end, and flares radially outward from the longitudinal axis and in such direction. A ring member extends around the axis of the elongate body and is spaced from the flared tip portion, and the ring member is adapted for retaining the elongate body in a position relative to a wall of the chamber. An embodiment of a flared tip portion may further include a barbed surface configured to contact tissue around an aperture in the wall of the heart when the cannula travels through the aperture.

Abstract: A fluid flow system for a patient comprises a controller and an implantable pump assembly. The controller comprises a processing unit and a battery. The processing unit includes a signal generator and one or more pump operational parameters. The signal generator provides a drive signal. The battery provides power to the processing unit. The implantable pump assembly receives the drive signal from the processing unit and propels fluid based on the drive signal. The system includes a local communication device and a remote communication device that each include a unique identifier produced by a security key generator. The remote communication device includes a code generator that produces encrypted commands. The local communication device receives the encrypted commands and modifies a pump operational parameter of the processing unit based on the received encrypted command.

Abstract: The invention relates to an arrangement having a blood pump and a gas exchanger for extracorporeal membrane oxygenation. According to the invention, the blood pump is designed as a pulsatile blood pump and is arranged with the gas exchanger in the same housing. The pulsatile blood pump and the gas exchanger are preferably connected to the same gas source so that the blood pump can be pneumatically driven. The novel ECMO system has a simple design, is flexible, and in particular can be used directly on the patient.

Abstract: A system for facilitating fluid connection between cannulae and a blood pump. The system includes a cannula having proximal and distal ends. The distal end of the cannula adapted to be in fluid communication with the circulatory system. The proximal end of the cannula configured to couple to an inlet of the blood pump. The system further includes a tunneling device configured to be inserted into a body of a patient to direct the proximal end of the cannula adjacent to the inlet for connection thereto. The cannula further includes a first connecting structure. The tunneling device further includes a second connecting structure. The first and second connecting structures are selectively engageable to allow connection and disconnection between the cannula and tunneling device.

Abstract: The invention relates to an arrangement having a blood pump and a gas exchanger for extracorporeal membrane oxygenation. According to the invention, the blood pump is designed as a pulsatile blood pump and is arranged with the gas exchanger in the same housing. The pulsatile blood pump and the gas exchanger are preferably connected to the same gas source so that the blood pump can be pneumatically driven. The novel ECMO system has a simple design, is flexible, and in particular can be used directly on the patient.

Abstract: A system for pumping blood in a patient comprises multiple components including a rotational drive assembly; a fluid drive element; a housing, an inflow cannula assembly and an outflow graft assembly. The inflow cannula assembly comprises an inflow conduit and an inflow connector. The outlet graft assembly comprises an outflow conduit and an outflow connector. The housing surrounds the fluid drive element and comprises an inflow port and an outflow port. The inflow conduit comprises a first end operably attachable to the inflow port and a second end fluidly connectable to a source of oxygenated blood. The outflow conduit comprises a first end operably attachable to the outflow port and a second end fluidly connectable to a blood vessel. The inflow connector operably connects the inflow conduit to the inflow port. The outflow connector operably connects the outflow conduit to the outflow port.

Abstract: An implantable blood pump, a blood pump system, and a method for data transfer in a blood pump system. By integrating the electronic components into the blood pump, they are located in the direct vicinity of corresponding component parts. An accumulation of heat is prevented by arranging the electronics on blood-guiding components of the blood pump, in particular on the cannula. This results in efficient cooling of the electronic components.

Abstract: A cannula for insertion through a biologic tissue. The cannula includes a shaft having proximal and distal end portions with a lumen therebetween. The cannula further includes a tip having a proximal end portion, a distal tip end, and a lumen therebetween. The proximal end portion of the tip is secured to the distal end portion of the shaft so that the lumen of the tip is in fluid communication with the lumen of the shaft. The tip includes an opening that extends proximally relative to the distal tip end to permit the flow of fluid into the lumen of the tip even in the event that the distal tip end becomes obstructed.

Abstract: A cannula for insertion through a biologic tissue. The cannula includes a shaft having proximal and distal end portions with a lumen therebetween. The cannula further includes a tip having a proximal end portion, a distal tip end, and a lumen therebetween. The proximal end portion of the tip is secured to the distal end portion of the shaft so that the lumen of the tip is in fluid communication with the lumen of the shaft. The tip includes an opening that extends proximally relative to the distal tip end to permit the flow of fluid into the lumen of the tip even in the event that the distal tip end becomes obstructed.