Abstract: There is disclosed a photogrammetry system for tracking the position of targets in real-time, using an extensible network of nodes, each of which comprises a stereoscopic camera assembly and a processor configured to process stereoscopic images to generate target data representing the positions of the targets. The target data may then be sent to a hub controller for determining global positions of the targets based on the target data generated at each node.

Abstract: A powder for use in a powder jet device for cleaning tooth surfaces by powder spraying, where the powder comprises at least 90 wt.-% of particles of a first material and 0.1-10 wt.-% of a second material, where the second material is coated on a surface of the particles of the first material and a solubility of the first material in water is ?1 g/L.

Abstract: An input system according to one aspect of the present disclosure comprises an electronic pen having a pen tip; and an electronic device configured to detect a pointed position of the electronic pen based on a detection signal received pursuant to an approach by the pen tip toward the electronic device. The electronic device includes: a planar sensor configured to acquire the detection signal; a flexible cover provided above the planar sensor and exposed to the outside; an actuator configured to displace the cover at each of multiple positions in an area defined by the planar sensor in at least a direction normal to the planar sensor; and a drive controller configured to perform drive control of the actuator so as to form local unevenness at a position of the cover corresponding to the pointed position of the electronic pen.

Abstract: The present invention relates to 1,3-thiazol-2-yl substituted benzamide compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neurogenic disorder, as a sole agent or in combination with other active ingredients.

Abstract: The present invention covers P2X3 inhibitor compounds of general formula (I) in which R1 and R2 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic disorders, as a sole agent or in combination with other active ingredients.

Abstract: A method of recovering organic components from an aqueous biomass in the method includes: (i) providing an aqueous biomass containing organic components; (ii) treatment of the aqueous biomass to release intracellular organic components from within cells of the biomass to form a biomass suspension; addition of a water-immiscible component to the biomass suspension to form a mixture comprising biomass and water-immiscible component; (iv) subjecting the mixture comprising biomass and water-immiscible component to high shear to form a water-in-water-immiscible-component emulsion; and (v) separating the water-immiscible component phase from the water/aqueous phase.

Abstract: The present invention is related to agonist of adiponectin receptor 1 (AdipoR1) and/or adiponectin receptor 2 (AdipoR2) for the treatment and/or prevention of polycystic ovary syndrome (PCOS).

Abstract: The present invention covers substituted. Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.

Abstract: An input system according to one aspect of the present disclosure comprises an electronic pen having a pen tip; and an electronic device configured to detect a pointed position of the electronic pen based on a detection signal received pursuant to an approach by the pen tip toward the electronic device. The electronic device includes: a planar sensor configured to acquire the detection signal; a flexible cover provided above the planar sensor and exposed to the outside; an actuator configured to displace the cover at each of multiple positions in an area defined by the planar sensor in at least a direction normal to the planar sensor; and a drive controller configured to perform drive control of the actuator so as to form local unevenness at a position of the cover corresponding to the pointed position of the electronic pen.

Abstract: An input system according to one aspect of the present disclosure comprises an electronic pen having a pen tip; and an electronic device configured to detect a pointed position of the electronic pen based on a detection signal received pursuant to an approach by the pen tip toward the electronic device. The electronic device includes: a planar sensor configured to acquire the detection signal; a flexible cover provided above the planar sensor and exposed to the outside; an actuator configured to displace the cover at each of multiple positions in an area defined by the planar sensor in at least a direction normal to the planar sensor; and a drive controller configured to perform drive control of the actuator so as to form local unevenness at a position of the cover corresponding to the pointed position of the electronic pen.

Abstract: An input system according to one aspect of the present disclosure comprises an electronic pen having a pen tip; and an electronic device configured to detect a pointed position of the electronic pen based on a detection signal received pursuant to an approach by the pen tip toward the electronic device. The electronic device includes: a planar sensor configured to acquire the detection signal; a flexible cover provided above the planar sensor and exposed to the outside; an actuator configured to displace the cover at each of multiple positions in an area defined by the planar sensor in at least a direction normal to the planar sensor; and a drive controller configured to perform drive control of the actuator so as to form local unevenness at a position of the cover corresponding to the pointed position of the electronic pen.

Abstract: The present invention covers substituted. Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.

Abstract: The present invention relates to 1,3-thiazol-2-yl substituted benzamide compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neurogenic disorder, as a sole agent or in combination with other active ingredients.

Abstract: The present invention relates to use 1,3-thiazol-2-yl substituted benzamide compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds for the treatment or prophylaxis of diseases which are associated with nerve fiber sensitization, and/or other pathological conditions associated with autonomic imbalance caused by increased chemoreceptor sensitivity, in particular for the treatment of breathing disorders, Cheyne Stokes respiration, central and obstructive sleep apnea, cardiovascular disease, hypertension, resistant hypertension, and heart failure, which are related to increased activity of P2X3 receptors.

Abstract: The present invention relates to use 1,3-thiazol-2-yl substituted benzamide compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds for the treatment or prophylaxis of diseases which are associated with nerve fibre sensitization, in particular for treatment and prophylaxis of Chronic Cough (CC), Idiopathic Pulmonary Fibrosis (IPF), Chronic Obstructive Pulmonary Disorder (COPD), and asthma.

Abstract: The invention relates to a process for methanol synthesis comprising the steps of providing a syngas feed stream comprising hydrogen and a mixture of carbon dioxide and carbon monoxide, wherein carbon dioxide represents from 1 to 50 mol % of the total molar content of the feed stream, carbon monoxide is contained from 0.1 to 85 mol % of the total molar content, and H2 is comprised from 5 to 95 mol % of the total molar content of the feed stream; providing an indium oxide catalyst selected from a bulk catalyst and a supported catalyst comprising indium oxide (In2O3) as the main active phase; putting in contact said stream with said catalyst at a reaction temperature of at least 373 K (99.85° C.) and under a pressure ranging of at least 1 MPa; and recovering the methanol effluents. The invention also relates to an indium oxide based catalyst.

Abstract: The invention relates to a process for methanol synthesis comprising the steps of providing a syngas feed stream comprising hydrogen and carbon oxides selected from carbon dioxide or a mixture of carbon dioxide and carbon monoxide, wherein carbon dioxide represents from 1 to 50 mol % of the total molar content of the feed stream, carbon monoxide is contained from 0 to 85 mol % of the total molar content, and H2 is comprised from 5 to 95 mol % of the total molar content of the feed stream, and a catalyst comprising indium oxide (In2O3) on a support wherein the support comprises zirconium dioxide or is zirconium dioxide; putting in contact said stream with said supported catalyst at a reaction temperature of at least 373 K (99.85° C.) and under a pressure ranging of at least 1 MPa; and recovering the methanol effluents. The invention also relates to a supported indium oxide catalyst.

Abstract: The present invention relates to 1,3-thiazol-2-yl substituted benzamide compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neurogenic disorder, as a sole agent or in combination with other active ingredients.

Abstract: A system for controlling movement of a device comprises at least one processor configured to receive a first input from a sensor upon detection of an obstacle in a first region of the device and a different second input from the sensor upon detection of the object in a different second region of the device and further configured to transmit a first signal to at least one actuator upon receiving the first input from the sensor, the first signal including a strength of first value and transmit a second signal upon receiving the second input from the sensor, the second value being greater than the first value.

Abstract: The invention relates to a process for methanol synthesis comprising the steps of providing a syngas feed stream comprising hydrogen and carbon oxides selected from carbon dioxide or a mixture of carbon dioxide and carbon monoxide, wherein carbon dioxide represents from 1 to 50 mol % of the total molar content of the feed stream, carbon monoxide is contained from 0 to 85 mol % of the total molar content, and H2 is comprised from 5 to 95 mol % of the total molar content of the feed stream, and a catalyst comprising indium oxide (In2O3) on a support wherein the support comprises zirconium dioxide or is zirconium dioxide; putting in contact said stream with said supported catalyst at a reaction temperature of at least 373 K (99.85° C.) and under a pressure ranging of at least 1 MPa; and recovering the methanol effluents. The invention also relates to a supported indium oxide catalyst.