Abstract: The invention provides gene therapy vectors, such as adeno-associated vims (AAV) vectors, expressing a functional fragment of the miniaturized human micro-dystrophin gene and method of using these vectors to express the fragment of micro-dystrophin in skeletal muscles including diaphragm and cardiac muscle and to protect muscle fibers from injury, increase muscle strength and reduce and/or prevent fibrosis in subjects suffering from muscular dystrophy.

Abstract: The invention relates to an assembly module (20) for a motor vehicle (1), comprising an optical sensor system (30) which can be used a) to monitor a detection area (150) on the outside of the motor vehicle (1) in order to determine the proximity of a user (10), b) to measure the distance to the user (10) within the detection area (150) and c) to release a signal for carrying out an action on the motor vehicle (1) in the event a user (10) is detected in a predefined actuation area (180) within the detection area (150).

Abstract: The invention relates to an assembly module (20) for a motor vehicle, comprising an optical sensor system (30), which can be used to a) monitor a detection area (21) on the outside of the motor vehicle (1) in order to determine the proximity of a user (10), b) in the event a user (10) is detected in the detection area (21), a signal for starting an authentication test between an ID transmitter (13) and an access control system (14) of the motor vehicle (1) is triggered.

Abstract: The invention relates to an emblem (80) for a motor vehicle (1), comprising an optical sensor system (30) which is suitable for a) monitoring a detection region (21) lying outside of the motor vehicle (1), b) triggering a signal for starting an authentication check between an ID transmitter (13) and the motor vehicle (1) in the event that a user (10) is detected in the detection region (21), c) monitoring an actuation region (22) which lies outside of the motor vehicle (1) and which differs from the detection region (21), and d) providing an operating signal for the motor vehicle (1) in the event that a user (10) is detected in the actuation region (22).

Abstract: The disclosure relates to a pixel array for an electrofluidic display element, comprising a plurality of adjacent pixels that form the pixel array, each pixel having a pixel chamber with a polygonal, preferably rectangular, pixel surface and a height. Each pixel has at least one main reservoir channel which opens, via a first width (D) and length (L), into the pixel chamber and a single- or multi-part reservoir channel which surrounds the chamber, borders the pixel surface and opens, along its length and a second width into the pixel chamber. A polar and/or electrically conductive liquid is or can be held in the pixels, said liquid being capable of motion back-and-forth between the reservoir channels and the pixel chamber by the application of an electric field, and the reservoir channels surrounding adjacent pixels run towards each other in a corner region in which the adjacent pixels border one another.

Abstract: A diamine compound of formula (I) is proposed as well as polymers, copolymers, polyamic acids, polyamic acid esters, or polyimides based on such compound.

Abstract: The invention concerns a method (70) for preparing an operating signal for a motor vehicle (1), the method involving the following steps: (a) obtaining a signal indicating that an authorized user (10) has been authenticated; (b) monitoring an actuating region (22) located outside the motor vehicle (1) by means of an optical sensor system (30); (c) measuring a distance (a) between an object (18) in the actuating region (22) and an optical sensor (50) by means of the optical sensor system (30); (d) comparing the distance (a) with a default by means of the optical sensor system (30); and (e) preparing an operating signal if the default is satisfied.

Abstract: The present invention relates to Abhydrolase containing domain 5 (ABHDS) and N-terminal fragments of HDAC4 (HDAC4-NT) and variants of the aforementioned peptides for the treatment and prevention of heart failure. The present invention further provides vectors for the cardiomyocyte-specific expression of said peptides and a test system comprising ABHDS for the identification of novel compounds which are useful for the treatment of heart failure.

Abstract: The invention relates to an assembly module (20) for a motor vehicle (1), said assembly module having an optical sensor system (30) which is suitable a) for monitoring an activation region (22) outside of the motor vehicle (1) during an activation duration in order to identify a user's intention in the activation region (22), b) for providing a working signal in the case that a user's intention has been identified. According to the invention, auxiliary means (31, 43, 45, 80) are provided which help the user (10) to make the user's intention in the activation region (22, 28) known so that the working signal can be provided.

Abstract: The invention relates to an assembly module (20) for a motor vehicle (1), comprising an optical sensor system (30) which is suitable for: a) monitoring a detection region (150) lying outside of the motor vehicle (1) in order to determine the proximity of a user (10), b) in the event of a detection of the user (10) in the detection region (150), monitoring an activation region (160) arranged within the detection region (150) in order to determine whether the user (10) is located within the activation region (160), and c) in the event of a detection of the user (10) in the activation region (160), triggering a signal for the execution of an action at the motor vehicle (1).

Abstract: The present invention relates to Abhydrolase containing domain 5 (ABHD5) and N-terminal fragments of HDAC4 (HDAC4-NT) and variants of the aforementioned peptides for the treatment and prevention of heart failure. The present invention further provides vectors for the cardiomyocyte-specific expression of said peptides and a test system comprising ABHD5 for the identification of novel compounds which are useful for the treatment of heart failure.

Abstract: The invention concerns an electrically controllable display element (1) for an optical display device, with a structured layer (2) that has a plurality pixels (3), and with at least one electrode layer (6) directly or indirectly over a structured side (2.1) of the structured layer (2), as well as with an active matrix (7) having thin film transistors, which has selectively controllable electrodes, such that individual or multiple particular pixels (3) can be charged with an electric field, characterized by the fact that the at least one electrode layer (6) extends in one piece over the structured side (2.1) of the structured layer (2), and that the active matrix (7) in the viewing direction is arranged on the display element (1) above the electrode layer (6).

Abstract: The invention relates to an assembly module (20) for a motor vehicle (1), comprising an optical sensor system (30) which is suitable for: a) monitoring a detection region (150) lying outside of the motor vehicle (1) in order to determine the proximity of a user (10), b) in the event of a detection of the user (10) in the detection region (150), monitoring an activation region (160) arranged within the detection region (150) in order to determine whether the user (10) is located within the activation region (160), and c) in the event of a detection of the user (10) in the activation region (160), triggering a signal for the execution of an action at the motor vehicle (1).

Abstract: The invention relates to an assembly module (20) for a motor vehicle (1), comprising an optical sensor system (30) which can be used a) to monitor a detection area (150) on the outside of the motor vehicle (1) in order to determine the proximity of a user (10), b) to emit a flash of laser light within the detection area (150), c) to detect a reflection of the flash of laser light (122) from the user (10) and d) to release a signal for carrying out an action on the motor vehicle (1) in the event a user (10) is detected in a predefined actuation area (180) within the detection area (150).

Abstract: The invention relates to a mounted module (20) for a motor vehicle (1), comprising an optical sensor system (3) that is suitable for a) monitoring a detection area (21) located outside the vehicle (1), b) triggering a signal for starting an authentication process between an ID generator (13) and the motor vehicle (1) if a user (10) is detected in the detection area (21), c) monitoring an actuation area (22) which is located outside the vehicle (1) and differs from the detection area (21), d) providing an operating signal for the vehicle (1) if a user is detected in the actuation area (22).

Abstract: The invention relates to an emblem (80) for a motor vehicle (1), comprising an optical sensor system (30) which is suitable for a) monitoring a detection region (21) lying outside of the motor vehicle (1), b) triggering a signal for starting an authentication check between an ID transmitter (13) and the motor vehicle (1) in the event that a user (10) is detected in the detection region (21), c) monitoring an actuation region (22) which lies outside of the motor vehicle (1) and which differs from the detection region (21), and d) providing an operating signal for the motor vehicle (1) in the event that a user (10) is detected in the actuation region (22).

Abstract: The invention relates to an assembly module (20) for a motor vehicle (1), comprising an optical sensor system (30) which is suitable a) for monitoring a detection area (21) located outside of the vehicle (1), b) if a user (10) is detected in the detection area (21), for triggering a signal to commence an authentication check between an ID transponder (13) and the motor vehicle (1), c) for monitoring an actuation area (22) which is located outside of the vehicle (1) and which is different from the detection area (21), d) if a user (10) is detected in the actuation area (22), for providing a working signal for the vehicle (1), wherein an emergency actuation means (90) is provided for additionally triggering the working signal, which emergency actuation means is suitable e) for providing a working signal for the vehicle (1) via an activation of the emergency actuation means (90) by a body part (11, 12) of the user (10).

Abstract: The invention relates to an assembly module (20) for a motor vehicle, comprising an optical sensor system (30), which can be used to a) monitor a detection area (21) on the outside of the motor vehicle (1) in order to determine the proximity of a user (10), b) in the event a user (10) is detected in the detection area (21), a signal for starting an authentication test between an ID transmitter (13) and an access control system (14) of the motor vehicle (1) is triggered.

Abstract: The invention relates to an assembly module (20) for a motor vehicle (1), comprising an optical sensor system (30) which can be used a) to monitor a detection area (150) on the outside of the motor vehicle (1) in order to determine the proximity of a user (10), b) to measure the distance to the user (10) within the detection area (150) and c) to release a signal for carrying out an action on the motor vehicle (1) in the event a user (10) is detected in a predefined actuation area (180) within the detection area (150).

Abstract: The invention relates to an assembly module (20) for a motor vehicle (1), said assembly module having an optical sensor system (30) which is suitable a) for monitoring an activation region (22) outside of the motor vehicle (1) during an activation duration in order to identify a user's intention in the activation region (22), b) for providing a working signal in the case that a user's intention has been identified. According to the invention, auxiliary means (31, 43, 45, 80) are provided which help the user (10) to make the user's intention in the activation region (22, 28) known so that the working signal can be provided.