Patents by Inventor Oliver Ploettner
Oliver Ploettner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230279109Abstract: The invention provides anti-TIM3 antibodies and methods of using the same.Type: ApplicationFiled: March 20, 2023Publication date: September 7, 2023Applicant: Hoffmann-La Roche Inc.Inventors: Valeria Lifke, Guy Georges, Victor Levitsky, Oliver Ploettner, Stefan Seeber, Barbara Weiser, Ildiko Wuensche, Adrian Zwick
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Publication number: 20230183349Abstract: The present invention relates to anti-PD1 antibodies and methods of using the same.Type: ApplicationFiled: March 3, 2023Publication date: June 15, 2023Applicant: Hoffmann-La Roche Inc.Inventors: Joerg BENZ, Laura CODARRI DEAK, Stefan DENGL, Sebastian FENN, Jens FISCHER, Guy GEORGES, Christian KLEIN, Viktor LEVITSKI, Valeria LIFKE, Oliver PLOETTNER, Stefan SEEBER, Barbara WEISER, Ildiko WUENSCHE, Adrian ZWICK
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Publication number: 20230143310Abstract: The present invention relates to anti-PD1 antibodies and methods of using the same.Type: ApplicationFiled: June 30, 2022Publication date: May 11, 2023Applicant: Hoffmann-La Roche Inc.Inventors: JOERG BENZ, LAURA CODARRI DEAK, STEFAN DENGL, SEBASTIAN FENN, JENS FISCHER, GUY GEORGES, CHRISTIAN KLEIN, VIKTOR LEVITSKI, VALERIA LIFKE, OLIVER PLOETTNER, STEFAN SEEBER, BARBARA WEISER, ILDIKO WUENSCHE, ADRIAN ZWICK
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Patent number: 11591383Abstract: Herein is reported a nucleic acid comprising in 5? to 3? direction i) a first nucleic acid fragment encoding a polypeptide of interest without an in frame translational stop codon, ii) a second nucleic acid fragment operably linked to said first nucleic acid fragment which is beginning with the 5? splice donor site of an immunoglobulin heavy chain CH3 or CH4 domain and which is terminated by the 3? splice acceptor site of the succeeding immunoglobulin heavy chain transmembrane domain exon M1 and which comprises in frame translational stop codon and a polyadenylation signal, and iii) a third nucleic acid fragment operably linked to said second nucleic acid encoding at least a fragment of a transmembrane domain, wherein the second nucleic acid fragment has at its 3? terminus the nucleotide sequence CTACCACCCCCTTCCTGTCCAG (SEQ ID NO: 29) or TGACCACGCCAATCGTGTCCAG (SEQ ID NO: 14) or CTACCACGCCAATCGTGTCCAG (SEQ ID NO: 31).Type: GrantFiled: March 28, 2019Date of Patent: February 28, 2023Assignee: Hoffmann-La Roche Inc.Inventors: Erhard Kopetzki, Oliver Ploettner
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Publication number: 20220363755Abstract: The invention provides anti-TIM3 antibodies and methods of using the same.Type: ApplicationFiled: December 20, 2021Publication date: November 17, 2022Applicant: Hoffmann-La Roche Inc.Inventors: Valeria Lifke, Guy Georges, Victor Levitsky, Oliver Ploettner, Stefan Seeber, Barbara Weiser, Ildiko Wuensche, Adrian Zwick
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Publication number: 20200157189Abstract: Herein is reported a nucleic acid comprising in 5? to 3? direction i) a first nucleic acid fragment encoding a polypeptide of interest without an in frame translational stop codon, ii) a second nucleic acid fragment operably linked to said first nucleic acid fragment which is beginning with the 5? splice donor site of an immunoglobulin heavy chain CH3 or CH4 domain and which is terminated by the 3? splice acceptor site of the succeeding immunoglobulin heavy chain transmembrane domain exon M1 and which comprises in frame translational stop codon and a polyadenylation signal, and iii) a third nucleic acid fragment operably linked to said second nucleic acid encoding at least a fragment of a transmembrane domain, wherein the second nucleic acid fragment has at its 3? terminus the nucleotide sequence CTACCACCCCCTTCCTGTCCAG (SEQ ID NO: 29) or TGACCACGCCAATCGTGTCCAG (SEQ ID NO: 14) or CTACCACGCCAATCGTGTCCAG (SEQ ID NO: 31).Type: ApplicationFiled: March 28, 2019Publication date: May 21, 2020Applicant: Hoffmann-La Roche Inc.Inventors: Erhard Kopetzki, Oliver Ploettner
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Publication number: 20190382480Abstract: The invention provides anti-TIM3 antibodies and methods of using the same.Type: ApplicationFiled: February 6, 2019Publication date: December 19, 2019Applicant: Hoffmann-La Roche Inc.Inventors: Valeria Lifke, Guy Georges, Victor Levitsky, Oliver Ploettner, Stefan Seeber, Barbara Weiser, Ildiko Wuensche, Adrian Zwick
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Publication number: 20190382489Abstract: The present invention relates to anti-PD1 antibodies and methods of using the same.Type: ApplicationFiled: December 18, 2018Publication date: December 19, 2019Applicant: Hoffmann-La Roche Inc.Inventors: JOERG BENZ, LAURA CODARRI DEAK, STEFAN DENGL, SEBASTIAN FENN, JENS FISCHER, GUY GEORGES, CHRISTIAN KLEIN, VIKTOR LEVITSKI, VALERIA LIFKE, OLIVER PLOETTNER, STEFAN SEEBER, BARBARA WEISER, ILDIKO WUENSCHE, ADRIAN ZWICK
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Publication number: 20180072804Abstract: The invention provides anti-TIM3 antibodies and methods of using the same.Type: ApplicationFiled: April 21, 2017Publication date: March 15, 2018Applicant: Hoffmann-La Roche Inc.Inventors: Valeria Lifke, Guy Georges, Victor Levitsky, Oliver Ploettner, Stefan Seeber, Barbara Weiser, Ildiko Wuensche, Adrian Zwick
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Publication number: 20170247454Abstract: The present invention relates to anti-PD1 antibodies and methods of using the same.Type: ApplicationFiled: September 29, 2016Publication date: August 31, 2017Applicant: Hoffmann-La Roche Inc.Inventors: Joerg Benz, Laura Codarri Deak, Stefan Dengl, Sebastian Fenn, Jens Fischer, Guy Georges, Christian Klein, Viktor Levitski, Valeria Lifke, Oliver Ploettner, Stefan Seeber, Barbara Weiser, Ildiko Wuensche, Adrian Zwick
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Publication number: 20160257749Abstract: The invention provides anti-TIM3 antibodies and methods of using the same.Type: ApplicationFiled: November 6, 2015Publication date: September 8, 2016Applicant: HOFFMANN-LA ROCHE, INC.Inventors: Valeria Lifke, Guy Georges, Victor Levitsky, Oliver Ploettner, Stefan Seeber, Barbara Weiser, Ildiko Wuensche, Adrian Zwick
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Patent number: 8541204Abstract: The current invention describes a nucleic acid comprising in a 5? to 3? direction a) a first nucleic acid encoding a heterologous polypeptide without an in frame stop codon, b) a second nucleic acid beginning with a 5? splice donor site and terminated by a 3? splice acceptor site comprising an in frame translational stop codon and a polyadenylation signal, and c) a nucleic acid encoding i) at least a fragment of a transmembrane domain, or ii) a signal peptide for a GPI-anchor.Type: GrantFiled: December 5, 2012Date of Patent: September 24, 2013Assignee: Hoffmann-La Roche Inc.Inventors: Josef Endl, Erhard Kopetzki, Oliver Ploettner, Ursula Schwarz, Georg Tiefenthaler
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Patent number: 8354516Abstract: The current invention describes a nucleic acid comprising in a 5? to 3? direction a) a first nucleic acid encoding a heterologous polypeptide without an in frame stop codon, b) a second nucleic acid beginning with a 5? splice donor site and terminated by a 3? splice acceptor site comprising an in frame translational stop codon and a polyadenylation signal, and c) a nucleic acid encoding i) at least a fragment of a transmembrane domain, or ii) a signal peptide for a GPI-anchor.Type: GrantFiled: May 15, 2007Date of Patent: January 15, 2013Assignee: Hoffmann-La Roche Inc.Inventors: Josef Endl, Erhard Kopetzki, Oliver Ploettner, Ursula Schwarz, Georg Tiefenthaler
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Patent number: 8314225Abstract: The current invention comprises a nucleic acid encoding the amino acid sequence of the C-terminal part of the CH3-domain of an immunoglobulin of the class IgA or IgG, or the C-terminal part of the CH4-domain of an immunoglobulin of the class IgE or IgM, wherein the glycine-lysine-dipeptide comprised in the amino acid sequence of the C-terminal part of the CH3- or CH4-domain is encoded by the nucleic acid ggaaaa, or the nucleic acid ggcaaa, or the nucleic acid gggaaa, or the nucleic acid gggaag, or the nucleic acid ggcaag, or the nucleic acid ggaaag.Type: GrantFiled: June 25, 2008Date of Patent: November 20, 2012Assignee: Hoffman-La Roche Inc.Inventors: Ulrich Goepfert, Silke Hansen, Hendrik Knoetgen, Erhard Kopetzki, Oliver Ploettner
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Publication number: 20100184144Abstract: The current invention comprises a nucleic acid encoding the amino acid sequence of the C-terminal part of the CH3-domain of an immunoglobulin of the class IgA or IgG, or the C-terminal part of the CH4-domain of an immunoglobulin of the class IgE or IgM, wherein the glycine-lysine-dipeptide comprised in the amino acid sequence of the C-terminal part of the CH3- or CH4-domain is encoded by the nucleic acid ggaaaa, or the nucleic acid ggcaaa, or the nucleic acid gggaaa, or the nucleic acid gggaag, or the nucleic acid ggcaag, or the nucleic acid ggaaag.Type: ApplicationFiled: June 25, 2008Publication date: July 22, 2010Inventors: Ulrich Goepfert, Silke Hansen, Hendrik Knoetgen, Erhard Kopetzki, Oliver Ploettner
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Publication number: 20090311725Abstract: The current invention describes a nucleic acid comprising in a 5? to 3? direction a) a first nucleic acid encoding a heterologous polypeptide without an in frame stop codon, b) a second nucleic acid beginning with a 5? splice donor site and terminated by a 3? splice acceptor site comprising an in frame translational stop codon and a polyadenylation signal, and c) a nucleic acid encoding i) at least a fragment of a transmembrane domain, or ii) a signal peptide for a GPI-anchor.Type: ApplicationFiled: May 15, 2007Publication date: December 17, 2009Inventors: Josef Endl, Erhard Kopetzki, Oliver Ploettner, Ursula Schwarz, Georg Tiefenthaler