Abstract: The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.

Abstract: The present invention relates to bispecific antibodies against ROR1 and CD3, their manufacture and use.

Abstract: Mixtures along with processes for making and uses for the same. The mixtures include organosilicon compounds, organic fibers, and/or thermoplastic polymers. The mixtures may optionally include polyolefins substituted by carboxylic acid anhydride groups and/or additives.

Abstract: A dialysis machine includes a leakage construction having a leakage collecting device and a leakage connector. The leakage connector is preferably a leakage adapter arranged between an opening of the leakage collecting device and a hose. The leakage connector has a main body to which a seal is attached, which can be brought into sealing contact with the leakage collecting device.

Abstract: A vehicle steering wheel system is provided. The system includes a steering wheel body with a hub region for attachment to a steering shaft of a vehicle steering system, a steering wheel rim and at least one spoke for attaching the steering wheel rim to the hub region; an electromechanical triggering device for triggering an acoustic output by means of an acoustic warning device of the vehicle, wherein the triggering device has an impact absorber cover and at least one force transducer wherein a force value threshold is predefined for each force transducer, and a wake-up signal is transmitted via the data connection to the evaluation unit if the force value threshold is exceeded by at least one force value, so that the latter changes from the energy-saving mode into the operating mode in which an actuating force value is determined by force value measured by the at least one force transducer.

Abstract: A composition includes thermoplastic polymers and at least one organosilicon compound of the general formula R3-a-b(OR1)aR2bSi[OSiR2]p[OSiRR2]q[OSiR22]rOSiR3-a-b(OR1)aR2b (I), wherein a+b is ?3 and at least one R2 radical is present.

Abstract: Low molecular weight silicone copolymers prepared by reacting an oxamido ester-terminated silicone with a polyetheramine and a primary or secondary amine are useful in treating fabrics to obtain a soft hand and also hydrophilicity, and can be prepared without the use of highly toxic reagents.

Abstract: A carrier-rail bus assembly including a number of n mechanically contiguous bus-circuit-plate sections electrically connected via bus-circuit paths and installed in a carrier rail, an electronic control unit being configured such that it detects whether an apparatus is inserted in an installation position i, respective installation position i being allotted a bus address, which is assigned to the apparatus inserted on the carrier rail on the respective bus-circuit-plate section in respective installation position i. A related method for assigning a bus address is also disclosed.

Abstract: Compositions having polyester-polysiloxane copolymers, containing (A) polyolefins which can optionally be substituted and (B) at least one organosilicon compound of the general formula R3-a-b(OR1)aR2 bSi[OSiR2]p[OSiRR2]q[OSiR2 2]rOSiR3-a-b(OR1)aR2 b (I). Along with methods of making the same and products made from the same.

Abstract: Oxamide-functional siloxanes are prepared by reacting (A) silanes of the general formula (I) with (B) siloxanes selected from (B1) linear siloxanes of the general formula HO[SiR2O]tH??(II) and (B2) cyclic compounds of the general formula (SiR42O)s??(III), in the presence of (C) catalysts.

Abstract: A colorant-containing composition includes (D) at least one colorant, (E) at least one siloxane-polyoxamide copolymer according to the general formula (IV), and optionally (F) additives. A process for producing a colorant-containing composition is also provided.

Abstract: Aqueous emulsions contain (A) oxamidoester-functionalized organopolysiloxanes having units of the formula R1a(OR2)bZcSiO(4?a?b?c)/2??(I) where Z is a group of the formula —Y—NRX—CO—CO—O—R3??(II), with the proviso that the sum a+b+c is ?3 and each molecule contains at least one radical Z. (B) emulsifiers and (C) water.

Abstract: Oxamidoester-functional alkylalkoxysilanes are prepared in high yield by the reaction of an alkylalkoxysilane with an oxalic diester.

Abstract: Methods and devices for insulation monitoring of an ungrounded IT power supply system having at least two phase conductors includes determining an insulation resistance separately for each phase conductor using a separate response value. In one embodiment of the invention, relevant current and voltage distributions are calculated. In another embodiment, a change time window is set within which a second response value is activated. In yet another embodiment, an option of shutting down/continuing operation of the IT power supply system is offered.

Abstract: A circuit arrangement (20) having an active measuring voltage (UG) for determining an insulation resistance (RF) or a complex-valued insulation impedance (ZF) of an ungrounded power supply system (12) against ground potential (PE), the circuit arrangement (20) having a measuring path (24) which runs between an active conductor (L1, L2) of the power supply system (12) and the ground potential (PE) and includes a measuring-voltage generator (VG) for generating the measuring voltage (UG), a measuring resistance (RM) for capturing a measured voltage (UM) and a coupling resistance (RA), the circuit arrangement (20) having a signal evaluation circuit (26) which includes a signal input for evaluating the measured voltage (UM) and a ground connection (GND). The ground connection (GND) is connected to a ground potential (PE).

Abstract: A carrier-rail bus assembly including a number of n mechanically contiguous bus-circuit-plate sections electrically connected via bus-circuit paths and installed in a carrier rail, an electronic control unit being configured such that it detects whether an apparatus is inserted in an installation position i, respective installation position i being allotted a bus address, which is assigned to the apparatus inserted on the carrier rail on the respective bus-circuit-plate section in respective installation position i. A related method for assigning a bus address is also disclosed.

Abstract: The disclosure relates to a drive means for non-resonant linear and/or rotary positioning of an object, comprising at least two piezoelectric or electrostrictive actuator groups, where-in a first actuator group moves a first runner portion relative to a stationary base of the drive means according to the principle of an inertia drive, and by means of the second actuator group a second runner portion is moved relative to the first runner portion with a limited range of movement in the high-resolution scan mode, wherein a common electrical control signal is applied to the first and second actuator groups.

Abstract: Oxamide-functional siloxanes are prepared by reacting (A) silanes of the general formula (I) with (B) siloxanes selected from (B1) linear siloxanes of the general formula HO[SiR2O]tH??(II) and (B2) cyclic compounds of the general formula (SiR42O)s??(III), in the presence of (C) catalysts.

Abstract: A method and device for determining a division of a total insulation resistance and of a total system leakage capacitance in an ungrounded power supply system. The basic idea is to determine how the total insulation resistance is divided into partial insulation resistances and how the total system leakage capacitance is divided into partial system leakage capacitances between the active conductors of the ungrounded power supply system from displacement voltages measured between each of the active conductors of the ungrounded power supply system based on values determined in advance for the total insulation resistance and for the total system leakage capacitance of the ungrounded power supply system. By evaluating the displacement voltages in terms of their changes in amplitude, their frequency and their phasing, conclusions can be drawn as to the division of the total insulation resistance and of the total system leakage capacitance between the individual active conductors.

Abstract: Low molecular weight silicone copolymers prepared by reacting an oxamido ester-terminated silicone with a polyetheramine and a primary or secondary amine are useful in treating fabrics to obtain a soft hand and also hydrophilicity, and can be prepared without the use of highly toxic reagents.