Abstract: Establishing communication between first and second digital twins, a first REST-based API assigned to the first digital twin and a second REST-based API assigned to the second digital twin includes transmitting a request to an endpoint of the first API and receiving a response therefrom, and transmitting a request to an endpoint of the second API and receiving a response therefrom. The responses are compared and analyzed. A mapping model is created on the basis of the comparing and analyzing, the mapping model containing semantic and technical requirements of the first API and of the second API. The mapping model is used for mutual communication between the first digital twin and the second digital twin, the mapping model translating a data transfer from one of the two digital twins in a manner conforming to the technical and semantic requirements of the API of the other of the two digital twins.

Abstract: A compound of Formula (1) is provided that has been shown to be useful for treating a disease caused by a viral infection: wherein R1, R2, R3, A, L, m, n, p and q are as defined herein.

Abstract: An optical monitoring system serves to monitor surroundings, having a monitoring apparatus, the visual or scanning field of which is captured by a lens, and a protection panel (112) which protects the lens from precipitation and covers at least the visual or scanning field of the monitoring apparatus. In order to avoid the signal quality of the monitoring apparatus being impaired by precipitation on the protection panel, it is proposed that the protection panel (12; 112; 218; 318) is acoustically coupled to at least one ultrasonic transducer (10). The optical monitoring system can be included into the control system of a vehicle for autonomous driving, wherein, overall, it is possible to obtain increased safety of the control system.

Abstract: A compound of Formula (I) is provided that has been shown to be useful for treating a disease caused by a viral infection: (I) wherein R1, R2, R3, A, L, m, n, p and q are as defined herein.

Abstract: A method of keeping a viewing area through a transparent element (10) of an optical monitoring device (100) clear, comprising the steps of: Forming a closed film (50) of a liquid on the transparent element (10); Coupling ultrasonic waves (64) into the transparent element (10), wherein loosening of contaminations (70) and/or adhesions to the transparent element (10) is promoted by the ultrasonic waves (64) coupled into the liquid film (50) and/or the transparent element (10).

Abstract: An optical monitoring system serves to monitor surroundings, having a monitoring apparatus, the visual or scanning field of which is captured by a lens, and a protection panel (112) which protects the lens from precipitation and covers at least the visual or scanning field of the monitoring apparatus. In order to avoid the signal quality of the monitoring apparatus being impaired by precipitation on the protection panel, it is proposed that the protection panel (12; 112; 218; 318) is acoustically coupled to at least one ultrasonic transducer (10). The optical monitoring system can be included into the control system of a vehicle for autonomous driving, wherein, overall, it is possible to obtain increased safety of the control system.

Abstract: An optical monitoring system serves to monitor surroundings, having a monitoring apparatus, the visual or scanning field of which is captured by a lens, and a protection panel (112) which protects the lens from precipitation and covers at least the visual or scanning field of the monitoring apparatus. In order to avoid the signal quality of the monitoring apparatus being impaired by precipitation on the protection panel, it is proposed that the protection panel (12; 112; 218; 318) is acoustically coupled to at least one ultrasonic transducer (10). The optical monitoring system can be included into the control system of a vehicle for autonomous driving, wherein, overall, it is possible to obtain increased safety of the control system.

Abstract: A vaporizer for vaporizing a liquid comprises a heating element for receiving electrical power and for delivering thermal power to a liquid to be vaporized and a temperature sensor for sensing the temperature of the heating element. The temperature sensor and the heating element are directly mechanically connected and thermally coupled.

Abstract: Aspects of the disclosure relate to cleaning rotating sensors having a sensor housing with a sensor input surface. For instance, a first signal indicating that there is a contaminant on the sensor input surface may be received. In response to receiving the first signal, a second signal may be sent in order to cause one or more transducers to generate waves in order to attempt to remove the contaminant from the sensor input surface.

Abstract: A device (1) for eliminating deposits and/or precipitation on a substrate (10, 110) comprises at least one transducer (20, 120) captively connected to the substrate (10, 110) by a connection layer (30), wherein the connection layer (30) is arranged between the substrate (10, 110) and the transducer (20, 120). The invention provides for the connection layer (30) to comprise a connection material (31) and a filling material (32). Furthermore, an optical system for environment monitoring comprising an optical monitoring device comprising a lens and/or an observation window and the above device is provided, wherein the lens or the observation window is formed by the substrate.

Abstract: Aspects of the disclosure relate to cleaning rotating sensors having a sensor housing with a sensor input surface. For instance, a first signal indicating that there is a contaminant on the sensor input surface may be received. In response to receiving the first signal, a second signal may be sent in order to cause one or more transducers to generate waves in order to attempt to remove the contaminant from the sensor input surface.

Abstract: A device (1) for eliminating deposits and/or precipitation on a substrate (10, 110) comprises at least one transducer (20, 120) captively connected to the substrate (10, 110) by a connection layer (30), wherein the connection layer (30) is arranged between the substrate (10, 110) and the transducer (20, 120). The invention provides for the connection layer (30) to comprise a connection material (31) and a filling material (32). Furthermore, an optical system for environment monitoring comprising an optical monitoring device comprising a lens and/or an observation window and the above device is provided, wherein the lens or the observation window is formed by the substrate.

Abstract: A compound of Formula (I) is provided that has been shown to be useful for treating a disease caused by a viral infection: (I) wherein R1, R2, R3, A, L, m, n, p and q are as defined herein.

Abstract: An optical monitoring system serves to monitor surroundings, having a monitoring apparatus, the visual or scanning field of which is captured by a lens, and a protection panel (112) which protects the lens from precipitation and covers at least the visual or scanning field of the monitoring apparatus. In order to avoid the signal quality of the monitoring apparatus being impaired by precipitation on the protection panel, it is proposed that the protection panel (12; 112; 218; 318) is acoustically coupled to at least one ultrasonic transducer (10). The optical monitoring system can be included into the control system of a vehicle for autonomous driving, wherein, overall, it is possible to obtain increased safety of the control system.

Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a Plasmodium parasite, such as malaria.

Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a Plasmodium parasite, such as malaria.

Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a Plasmodium parasite, such as malaria.

Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a Plasmodium parasite, such as malaria.

Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a Plasmodium parasite, such as malaria.

Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a Plasmodium parasite, such as malaria.