Abstract: This invention relates to compounds that can be used to treat viral infections. The compounds are papain-like protease (PLpro) inhibitors.

Abstract: Photodiode systems, methods, devices, and circuitries are provided for determining a material property and/or determining environmental characteristics. In one embodiment, a measurement device includes a first member, a second member rotatably coupled to the first member at a pivot that affixes the first member to the second member. The first member and the second member are configured to pivot between a closed position, where the first member and the second member contact one another, and an open position where the first member is rotatably separated from the second member. An infrared emitter is disposed within the first member, the infrared emitter faces the second member. An infrared sensor is disposed within the second member facing the first member, where when the first member and the second member are in the closed position, the infrared emitter and the infrared sensor are misaligned.

Abstract: Systems, methods, devices, and circuitries are provided for determining a material property. In one embodiment, a method includes applying non-thermal energy to a first side of a material sample; sensing, a response of the material sample to the non-thermal energy; generating non-thermal data indicative of the response; and determining a thermal property of the material sample based on the non-thermal data. In one embodiment, the method also includes determining an environmental characteristic; determining a suitability of the material sample based on the thermal property and the environmental characteristic; and displaying information related to the suitability.

Abstract: Acoustic systems, methods, devices, and circuitries are provided for determining a material property. In one embodiment, a method for a measurement system includes receiving a measurement report including acoustic data. The acoustic data is based on an acoustic signal received through a material sample. The method includes determining a first thermal property value of the material sample based on the acoustic data of the measurement report and generating an indication of the first thermal property value.

Abstract: Photodiode systems, methods, devices, and circuitries are provided for determining a material property and/or determining environmental characteristics. In one embodiment, a measurement device includes a first member, a second member rotatably coupled to the first member at a pivot that affixes the first member to the second member. The first member and the second member are configured to pivot between a closed position, where the first member and the second member contact one another, and an open position where the first member is rotatably separated from the second member. An infrared emitter is disposed within the first member, the infrared emitter faces the second member. An infrared sensor is disposed within the second member facing the first member, where when the first member and the second member are in the closed position, the infrared emitter and the infrared sensor are misaligned.

Abstract: Systems, methods, devices, and circuitries are provided for determining environmental characteristics. In one embodiment, a measurement device includes a housing. The housing includes a first member and a second member, where the first member and the second member are attached to one another by a clamping mechanism. A handle mechanism is connected to the clamping mechanism, where the clamping mechanism is between the handle mechanism and the first and second members. The handle mechanism has a first handle portion arranged over a second handle portion, and the first handle portion is separated from the second handle portion by a gap. A first environmental sensor is disposed within one of the first member or the second member, and a second environmental sensor is disposed within or protruding from the housing.

Abstract: Disclosed herein are expanding spinal fusion cage embodiments including an expandable cage assembly configured to expand from a collapsed state to an expanded state in an intervertebral space when inflated with a material. The assembly can include an inflatable section defining an interior volume configured to receive the material and expand the interior volume in response to a pressure from the received material to cause the expandable cage assembly to transition from the collapsed state to the expanded state, and a stabilization section configured to restrain the inflatable section during inflation.

Abstract: Systems, methods, devices, and circuitries are provided for determining a material property. In one embodiment, a method includes applying non-thermal energy to a first side of a material sample; sensing, a response of the material sample to the non-thermal energy; generating non-thermal data indicative of the response; and determining a thermal property of the material sample based on the non-thermal data.

Abstract: Systems, methods, devices, and circuitries are provided for determining a material property. In one embodiment, a method includes receiving an environmental characteristic value from a user; determining garment suitability information for the environmental characteristic value; and providing an indication of the garment suitability information to the user.

Abstract: Systems, methods, devices, and circuitries are provided for determining a material property. In one embodiment, a measurement device includes analysis circuitry and indicia circuitry. The analysis circuitry is configured to determine a sample thermal property value of a material sample; determine an environmental characteristic value; identify a range of environmental characteristic values mapped to the sample thermal property value; determine a suitability result corresponding to a suitability of the material sample to the environmental characteristic value based on whether the environmental characteristic value falls within the identified range of environmental characteristic values. The indicia circuitry is configured to communicate the suitability result.

Abstract: Disclosed herein are expanding spinal fusion cage embodiments including an expandable cage assembly configured to expand from a collapsed state to an expanded state in an intervertebral space when inflated with a material. The assembly can include an inflatable section defining an interior volume configured to receive the material and expand the interior volume in response to a pressure from the received material to cause the expandable cage assembly to transition from the collapsed state to the expanded state, and a stabilization section configured to restrain the inflatable section during inflation.

Abstract: Systems, methods, devices, and circuitries are provided for determining a material property. In one embodiment, a method includes applying non-thermal energy to a first side of a material sample; sensing, a response of the material sample to the non-thermal energy; generating non-thermal data indicative of the response; and determining a thermal property of the material sample based on the non-thermal data. In one embodiment, the method also includes determining an environmental characteristic; determining a suitability of the material sample based on the thermal property and the environmental characteristic; and displaying information related to the suitability.

Abstract: A medical ventilator (100, 200) including a first user interface (114) having a touch-sensitive display having a display area; and at least one controller (104) which determines whether a second user interface (122, 222) having a touch-sensitive display is coupled to the medical ventilator, enables the first user interface when it is determined that the second user interface is not coupled to the medical ventilator, and enables the second user interface when it is determined that the second user interface is coupled to the medical ventilator.

Abstract: The instant disclosure is directed to a method of lubricating a sump-lubricated, high efficiency, gasoline-fueled internal combustion engine. Said method involves supplying to the engine a lubricating composition comprising an oil of lubricating viscosity, an anti-wear agent, an ashless antioxidant, a metal-containing detergent, an ashless polyolefin dispersant, and (f) a polymeric viscosity modifier. The disclosure further provides a method of operating a high efficiency sump-lubricated gasoline-fueled internal combustion engine while maintaining or improving at least one of durability, deposit control, oxidation control, fuel economy, and resistance to knock and stochastic pre-ignition.

Abstract: A stretching machine of two seat having bases and backrests which is pivotally mounted to the base including a first leg platform having a pivot end and a free end, the pivot end being connected to the base of the seat and a second leg platform having a pivot end and a free end, the pivot end being connected to the base of the seat. The stretching machine includes a mechanism for rotating the backrest relative to the seat as well as a mechanism for rotating the leg platforms about their respective pivot ends such that the free ends move in a generally arcuate path.

Abstract: A medical ventilator (100, 200) including a first user interface (114) having a touch-sensitive display having a display area; and at least one controller (104) which determines whether a second user interface (122, 222) having a touch-sensitive display is coupled to the medical ventilator, enables the first user interface when it is determined that the second user interface is not coupled to the medical ventilator, and enables the second user interface when it is determined that the second user interface is coupled to the medical ventilator.

Abstract: Ultrasonic measurement apparatus 10 includes a transmitter 14 to transmit an ultrasonic signal 16 into an item 12. A receiver 18 receives echoes 20 from the item 12. The apparatus 10 measures the frequency spectrum of the echo 20 and makes a comparison with another frequency spectrum to extract information relating to a change in the item 12. For example, the item 12 may wear during use. A comparison of the frequency spectrum, with previous frequency spectra, allows changes of dimension of the item 12 to be identified. Changes in amplitudes of the frequency spectrum allow changes in roughness to be detected.