Patents by Inventor Oliver T. BRUNS

Oliver T. BRUNS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Short-wavelength infrared (SWIR) fluorescence in vivo and intravital imaging with semiconductor nanocrystals
    Patent number: 11077213
    Abstract: InAs based core-shell particles which leads to tunable, narrow emitting semiconductor nanocrystals with a very high quantum yield which can be preserved in physiological buffers with long stability can used for short wavelength infrared (SWIR) imaging. Increased resolution with reduced read time and increased imaging frequency can provide advantages in in vivo applications.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: August 3, 2021
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Moungi G. Bawendi, Daniel K. Harris, Oliver T. Bruns, Thomas S. Bischof
  • Nanoparticles for magnetic resonance imaging applications
    Patent number: 10758633
    Abstract: A method of preparing a coated nanoparticle can include decomposing a compound to produce a nanoparticle, oxidizing the nanoparticle to produce an oxidized nanoparticle, and coating the oxidized nanoparticle with a zwitterionic ligand to produce the coated nanoparticle. The coated nanoparticle or the nanoparticle can be used in magnetic resonance imaging.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: September 1, 2020
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: He Wei, Oliver T. Bruns, Ou Chen, Moungi G. Bawendi
  • TINY NANOPARTICLES FOR MAGNETIC RESONANCE IMAGING APPLICATIONS
    Publication number: 20200023084
    Abstract: A method of preparing a coated nanoparticle can include decomposing a compound to produce a nanoparticle, oxidizing the nanoparticle to produce an oxidized nanoparticle, and coating the oxidized nanoparticle with a zwitterionic ligand to produce the coated nanoparticle. The coated nanoparticle or the nanoparticle can be used in magnetic resonance imaging.
    Type: Application
    Filed: November 8, 2018
    Publication date: January 23, 2020
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Moungi G. Bawendi, He Wei, Oliver T. Bruns, Eric C. Hansen
  • NANOPARTICLES FOR MAGNETIC RESONANCE IMAGING APPLICATIONS
    Publication number: 20190022258
    Abstract: A method of preparing a coated nanoparticle can include decomposing a compound to produce a nanoparticle, oxidizing the nanoparticle to produce an oxidized nanoparticle, and coating the oxidized nanoparticle with a zwitterionic ligand to produce the coated nanoparticle. The coated nanoparticle or the nanoparticle can be used in magnetic resonance imaging.
    Type: Application
    Filed: October 1, 2018
    Publication date: January 24, 2019
    Applicant: Massachusetts Institute of Technology
    Inventors: He Wei, Oliver T. Bruns, Ou Chen, Moungi G. Bawendi
  • Nanoparticles for magnetic resonance imaging applications
    Patent number: 10086094
    Abstract: A method of preparing a coated nanoparticle can include decomposing a compound to produce a nanoparticle, oxidizing the nanoparticle to produce an oxidized nanoparticle, and coating the oxidized nanoparticle with a zwitterionic ligand to produce the coated nanoparticle. The coated nanoparticle or the nanoparticle can be used in magnetic resonance imaging.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: October 2, 2018
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: He Wei, Oliver T. Bruns, Ou Chen, Moungi G. Bawendi
  • NANOPARTICLES FOR MAGNETIC PARTICLE IMAGING APPLICATIONS
    Publication number: 20160136307
    Abstract: One method of preparing a nanoparticle can include decomposing a compound at a high temperature, adding an acid to the solvent to form a reaction mixture, increasing the temperature of the reaction mixture to boiling point of the reaction mixture, and heating the reaction mixture at the boiling point for 60 to 120 minutes to produce the nanoparticle. The coated nanoparticle or the nanoparticle can be used in magnetic particles imaging.
    Type: Application
    Filed: November 13, 2015
    Publication date: May 19, 2016
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: He Wei, Oliver T. Bruns, Ou Chen, Moungi G. Bawendi
  • NANOPARTICLES FOR MAGNETIC RESONANCE IMAGING APPLICATIONS
    Publication number: 20160074538
    Abstract: A method of preparing a coated nanoparticle can include decomposing a compound to produce a nanoparticle, oxidizing the nanoparticle to produce an oxidized nanoparticle, and coating the oxidized nanoparticle with a zwitterionic ligand to produce the coated nanoparticle. The coated nanoparticle or the nanoparticle can be used in magnetic resonance imaging.
    Type: Application
    Filed: September 11, 2015
    Publication date: March 17, 2016
    Inventors: He Wei, Oliver T. Bruns, Ou Chen, Moungi G. Bawendi
  • SHORT-WAVELENGTH INFRARED (SWIR) FLUORESCENCE IN VIVO AND INTRAVITAL IMAGING WITH SEMICONDUCTOR NANOCRYSTALS
    Publication number: 20150273085
    Abstract: InAs based core-shell particles which leads to tunable, narrow emitting semiconductor nanocrystals with a very high quantum yield which can be preserved in physiological buffers with long stability can used for short wavelength infrared (SWIR) imaging. Increased resolution with reduced read time and increased imaging frequency can provide advantages in in vivo applications.
    Type: Application
    Filed: April 22, 2014
    Publication date: October 1, 2015
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Moungi G. BAWENDI, Daniel K. HARRIS, Oliver T. BRUNS, Thomas S. BISCHOF