Patents by Inventor Oliver Thomas Bruns

Oliver Thomas Bruns has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Device and method for imaging shortwave infrared fluorescence
    Patent number: 11579088
    Abstract: Systems and methods for measuring short wave infrared fluorescence and autofluorescent signals are disclosed. In some embodiments, for example, a method may include exposing a portion of tissue that does not include a fluorescent probe to an excitation source of the tissue, wherein at least a portion of the tissue has an autofluorescence spectrum which includes wavelengths greater than 900 nm, and imaging the tissue with a detector that is sensitive to electromagnetic radiation with wavelengths greater than or equal to 900 nm. In certain other embodiments, a system comprises a fluorescent probe including a fluorescent component attached to a carrier, an excitation source, and a detector that detects a tail portion of the fluorescence of the fluorescent component. Methods associated with such a system are also disclosed.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: February 14, 2023
    Assignees: Massachusetts Institute of Technology, The General Hospital Corporation
    Inventors: Moungi G. Bawendi, Oliver Thomas Bruns, Jessica Ann Carr, Klaus van Leyen, Yi Zheng, Marianne Aellen
  • Device and method for imaging shortwave infrared fluorescence
    Patent number: 10996170
    Abstract: Systems and methods for measuring short wave infrared fluorescence and autofluorescent signals are disclosed.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: May 4, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Moungi G. Bawendi, Oliver Thomas Bruns, Tulio A. Valdez, Jessica Ann Carr, Daniel Franke, Marianne Aellen
  • DEVICE AND METHOD FOR IMAGING SHORTWAVE INFRARED FLUORESCENCE
    Publication number: 20200041417
    Abstract: Systems and methods for measuring short wave infrared fluorescence and autofluorescent signals are disclosed.
    Type: Application
    Filed: March 10, 2017
    Publication date: February 6, 2020
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Moungi G. Bawendi, Oliver Thomas BRUNS, Tulio A. VALDEZ, Jessica, Ann CARR, Daniel FRANKE, Marianne AELLEN
  • DEVICE AND METHOD FOR DETECTING DISEASE STATES ASSOCIATED WITH LIPOPIGMENTS
    Publication number: 20190307390
    Abstract: Systems and methods for measuring autofluorescent signals from lipopigments associated with various disease states are disclosed.
    Type: Application
    Filed: April 9, 2019
    Publication date: October 10, 2019
    Applicants: Massachusetts Institute of Technology, The General Hospital Corporation
    Inventors: Moungi G. Bawendi, Rakesh Jain, Oliver Thomas Bruns, Jessica Ann Carr, Klaus van Leyen, Wilhelmus Kwanten, Ivy Xiaoyu Chen
  • DEVICE AND METHOD FOR IMAGING SHORTWAVE INFRARED FLUORESCENCE
    Publication number: 20190079010
    Abstract: Systems and methods for measuring short wave infrared fluorescence and autofluorescent signals are disclosed.
    Type: Application
    Filed: March 10, 2017
    Publication date: March 14, 2019
    Applicants: Massachusetts Institute of Technology, The General Hospital Corporation d/b/a Massachusets General Hospital
    Inventors: Moungi G. Bawendi, Oliver Thomas Bruns, Jessica Ann Carr, Klaus van Leyen, Yi Zheng, Marianne Aellen
  • Metal oxide particles coated with polyethylene glycol and their synthesis
    Publication number: 20120201760
    Abstract: A T1 blood pool contrast agent comprising very small iron oxide nanoparticles are coated with poly(ethylene glycol) (PEG) based ligands. Core size and length of the PEG chain were optimized according to stability, relaxometric properties, cytotoxicity and unspecified cell uptake.
    Type: Application
    Filed: August 9, 2010
    Publication date: August 9, 2012
    Inventors: Ulrich Ingmar Tromsdorf, Oliver Thomas Bruns, Horst Weller