Patents by Inventor Oliver Wagner

Oliver Wagner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220313805
    Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
    Type: Application
    Filed: March 4, 2022
    Publication date: October 6, 2022
    Inventors: Andrea MAHR, Toni WEINSCHENK, Oliver SCHOOR, Jens FRITSCHE, Harpreet SINGH, Claudia WAGNER, Julia LEIBOLD, Colette SONG
  • Publication number: 20220285307
    Abstract: A semiconductor device includes a semiconductor wafer or a single semiconductor chip or die, and a layer stack. The layer stack comprises a first layer comprising NiSi, and a second layer comprising NiV, wherein the second layer is arranged between the first layer and the semiconductor wafer or single semiconductor chip or die.
    Type: Application
    Filed: March 7, 2022
    Publication date: September 8, 2022
    Inventors: Paul Frank, Thomas Heinelt, Oliver Schilling, Sven Schmidbauer, Frank Wagner
  • Patent number: 11399895
    Abstract: A method performed by a computing system comprises receiving, from a fluoroscopic imager, having a first set of parameters, first fluoroscopic image data of a first fiducial marker within a surgical coordinate space. The method comprises receiving a configuration of the first fiducial marker within the surgical coordinate space. The method comprises determining a second set of parameters of the fluoroscopic imager in the surgical coordinate space based on the first fluoroscopic image data and the configuration of the first fiducial marker. In some embodiments, determining the second set of parameters comprises developing a calibrated model of the fiducial marker in the surgical coordinate space from the first fluoroscopic image data and the configuration of the first fiducial marker.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: August 2, 2022
    Assignee: INTUITIVE SURGICAL OPERATIONS, INC.
    Inventors: Timothy D. Soper, Federico Barbagli, Caitlin Q. Donhowe, Vincent Duindam, Michael D. Paris, Oliver Wagner, Tao Zhao
  • Patent number: 11389268
    Abstract: A computer-assisted medical device includes a control unit, first and second articulated arms, a first imaging device mounted to the first articulated arm, and a medical tool mounted to the second articulated arm. The control unit obtains first images from a second imaging device using a first imaging modality, determines first coordinates of multi-modal anatomical markers secured to a patient based on the first images, obtains second images from the first imaging device using a second imaging modality, determines second coordinates of the multi-modal markers relative to the medical tool based on the second images, at least one of the multi-modal markers including a body comprising a first region observable by the first imaging modality and a second region observable by the second imaging modality, and registers the medical tool to the patient based on the first and second coordinates and kinematic models of the first and second articulated arms.
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: July 19, 2022
    Assignee: INTUITIVE SURGICAL OPERATIONS, INC.
    Inventors: Mahdi Azizian, Oliver Wagner
  • Publication number: 20220214158
    Abstract: An optical force sensor along with an optical processing apparatus and method are disclosed. The optical force sensor includes an optical fiber, a core included in the optical fiber, an instrument including the optical fiber, the instrument having a distal region, and a tubular structure encasing an end of the optical fiber and secured to the first conduit at the distal region of the instrument. When an optical interferometric system is coupled to the optical fiber, it processes reflected light from a portion of the core included within the tubular structure that does not include Bragg gratings to produce a measurement of a force present at the distal region of the instrument.
    Type: Application
    Filed: March 21, 2022
    Publication date: July 7, 2022
    Inventors: Dawn K. Gifford, Federico Barbagli, Samuel Chang, Anoop B. Kowshik, Oliver Wagner, Michael Paris, Mark Froggatt
  • Publication number: 20220211833
    Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
    Type: Application
    Filed: March 11, 2022
    Publication date: July 7, 2022
    Inventors: Andrea MAHR, Toni WEINSCHENK, Oliver SCHOOR, Jens FRITSCHE, Harpreet SINGH, Claudia WAGNER, Julia LEIBOLD, Colette SONG
  • Patent number: 11378020
    Abstract: A method for operating a reciprocating internal combustion engine in an engine braking mode includes, in a working cycle of the engine braking mode, a first outlet valve of a first cylinder is closed for a first time, then opened for a first time, and subsequently closed for a second time, and then opened for a second time, in order to thereby discharge gas that has been compressed in the first cylinder from the first cylinder by a cylinder piston. The outlet valve is held open after the first opening and prior to the second closing long enough for the cylinder to be filled with gas that flows out of a second cylinder via at least one outlet channel, where when the engine braking mode is activated, at least one camshaft for activating at least one gas exchange valve of the reciprocating internal combustion engine is adjusted.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: July 5, 2022
    Assignee: Daimler AG
    Inventor: Marc Oliver Wagner
  • Patent number: 11352914
    Abstract: A valve train of an internal combustion engine of a motor vehicle includes a rocker arm assigned to a first combustion chamber of the internal combustion engine where via the rocker arm a gas exchange valve assigned to the first combustion chamber is actuatable. An actuating device is assigned to a second combustion chamber of the internal combustion engine where via the actuating device, by supplying the actuating device with a hydraulic fluid, the second combustion chamber is switchable between a firing mode for fired operation and a braking mode for an engine braking operation of the internal combustion engine. A supply of the hydraulic fluid to the actuating device assigned to the second combustion chamber is adjustable by the rocker arm assigned to the first combustion chamber.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: June 7, 2022
    Assignee: Daimler AG
    Inventors: Marc Oliver Wagner, Josef Astner
  • Patent number: 11346415
    Abstract: A brake disc is provided for a disc brake, which consists of a brake disc chamber and at least one friction ring connected to the latter via connecting devices. A jacket of the brake disc chamber is provided with sections of reduced wall thickness and/or apertures. These sections and/or apertures are axially directed material recesses which are located on the outer circumference of the brake disc chamber jacket and serve for placing the connecting devices as close as possible to the brake disc chamber jacket.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: May 31, 2022
    Assignee: Bayerische Motoren Werke Aktiengesellschaft
    Inventors: Oliver Wagner, Thomas Graf, Kordian Kokott, Ulf Schulz, Matthias Stangl, Thomas Bambl, Richard Wagner, Stefan Bergmaier
  • Patent number: 11313674
    Abstract: An optical force sensor along with an optical processing apparatus and method are disclosed. The optical force sensor includes an optical fiber, a core included in the optical fiber, an instrument including the optical fiber, the instrument having a distal region, and a tubular structure encasing an end of the optical fiber and secured to the first conduit at the distal region of the instrument. When an optical interferometric system is coupled to the optical fiber, it processes reflected light from a portion of the core included within the tubular structure that does not include Bragg gratings to produce a measurement of a force present at the distal region of the instrument.
    Type: Grant
    Filed: December 8, 2020
    Date of Patent: April 26, 2022
    Assignee: Intuitive Surgical Operations, Inc.
    Inventors: Dawn K. Gifford, Federico Barbagli, Samuel Chang, Anoop B. Kowshik, Oliver Wagner, Michael Paris, Mark E. Froggatt
  • Publication number: 20210381400
    Abstract: A valve train of an internal combustion engine of a motor vehicle includes a rocker arm assigned to a first combustion chamber of the internal combustion engine where via the rocker arm a gas exchange valve assigned to the first combustion chamber is actuatable. An actuating device is assigned to a second combustion chamber of the internal combustion engine where via the actuating device, by supplying the actuating device with a hydraulic fluid, the second combustion chamber is switchable between a firing mode for fired operation and a braking mode for an engine braking operation of the internal combustion engine. A supply of the hydraulic fluid to the actuating device assigned to the second combustion chamber is adjustable by the rocker arm assigned to the first combustion chamber.
    Type: Application
    Filed: October 15, 2019
    Publication date: December 9, 2021
    Inventors: Marc Oliver WAGNER, Josef ASTNER
  • Publication number: 20210317794
    Abstract: A method for operating an internal combustion engine, in particular of a motor vehicle, in an engine braking operating, having at least one engine braking mode and having at least one cylinder at least of a first cylinder bank, where the at least one cylinder has at least one outlet valve and at least one inlet valve, where, in a first engine braking mode, an outlet stroke of all outlet valves of the at least one cylinder of the first cylinder bank of the internal combustion engine is permanently switched off.
    Type: Application
    Filed: July 4, 2019
    Publication date: October 14, 2021
    Applicant: Daimler AG
    Inventors: Marc Oliver WAGNER, Thomas SCHUHMACHER
  • Patent number: 11136926
    Abstract: A method for operating a reciprocating piston internal combustion engine in an engine braking mode includes moving an outlet valve of a first cylinder for a first time into a closed position, subsequently for a first time into an open position, subsequently in a direction of the closed position, and subsequently for a second time into the open position. The outlet valve is held open during the moving in the direction of the closed position for such a long time that the first cylinder is filled with gas which flows via an outlet duct out of a second cylinder. The outlet valve is moved, during the moving in the direction of the closed position, into an intermediate position which lies between the open position and the closed position, where from the intermediate position the outlet valve is moved for the second time into the open position.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: October 5, 2021
    Assignee: Daimler AG
    Inventors: Thomas Schuhmacher, Marc Oliver Wagner
  • Publication number: 20210231432
    Abstract: An optical force sensor along with an optical processing apparatus and method are disclosed. The optical force sensor includes an optical fiber, a core included in the optical fiber, an instrument including the optical fiber, the instrument having a distal region, and a tubular structure encasing an end of the optical fiber and secured to the first conduit at the distal region of the instrument. When an optical interferometric system is coupled to the optical fiber, it processes reflected light from a portion of the core included within the tubular structure that does not include Bragg gratings to produce a measurement of a force present at the distal region of the instrument.
    Type: Application
    Filed: December 8, 2020
    Publication date: July 29, 2021
    Inventors: Dawn K. Gifford, Federico Barbagli, Samuel Chang, Anoop B. Kowshik, Oliver Wagner, Michael Paris, Mark E. Froggatt
  • Publication number: 20210131357
    Abstract: A method for operating a reciprocating piston internal combustion engine in an engine braking mode includes moving an outlet valve of a first cylinder for a first time into a closed position, subsequently for a first time into an open position, subsequently in a direction of the closed position, and subsequently for a second time into the open position. The outlet valve is held open during the moving in the direction of the closed position for such a long time that the first cylinder is filled with gas which flows via an outlet duct out of a second cylinder. The outlet valve is moved, during the moving in the direction of the closed position, into an intermediate position which lies between the open position and the closed position, where from the intermediate position the outlet valve is moved for the second time into the open position.
    Type: Application
    Filed: September 20, 2017
    Publication date: May 6, 2021
    Applicant: Daimler AG
    Inventors: Thomas SCHUHMACHER, Marc Oliver WAGNER
  • Patent number: 10876831
    Abstract: An optical force sensor along with an optical processing apparatus and method are disclosed. The optical force sensor includes an optical fiber, a core included in the optical fiber, an instrument including the optical fiber, the instrument having a distal region, and a tubular structure encasing an end of the optical fiber and secured to the first conduit at the distal region of the instrument. When an optical interferometric system is coupled to the optical fiber, it processes reflected light from a portion of the core included within the tubular structure that does not include Bragg gratings to produce a measurement of a force present at the distal region of the instrument.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: December 29, 2020
    Assignee: Intuitive Surgical Operation, Inc.
    Inventors: Dawn K. Gifford, Federico Barbagli, Samuel Chang, Anoop B. Kowshik, Oliver Wagner, Michael Paris, Mark E. Froggatt
  • Patent number: 10598099
    Abstract: A method for operating a reciprocating internal combustion engine in an engine braking mode of operation is provided. The method includes closing, for a first time, at least one exhaust valve of at least one cylinder in the engine braking mode of operation within a working cycle, and opening for a first time, and closing, for a second time, the at least one exhaust valve of the at least one cylinder, and opening for a second time to thereby discharge compressed gas in the cylinder via a piston of the cylinder from the cylinder. After the first opening and before the second closing, the exhaust valve is kept open, until the cylinder is filled with gas which flows through at least one exhaust channel from at least one second cylinder of the reciprocating internal combustion engine.
    Type: Grant
    Filed: December 4, 2014
    Date of Patent: March 24, 2020
    Assignee: Daimler AG
    Inventors: Marc Oliver Wagner, Alexander Zink
  • Publication number: 20190331478
    Abstract: An optical force sensor along with an optical processing apparatus and method are disclosed. The optical force sensor includes an optical fiber, a core included in the optical fiber, an instrument including the optical fiber, the instrument having a distal region, and a tubular structure encasing an end of the optical fiber and secured to the first conduit at the distal region of the instrument. When an optical interferometric system is coupled to the optical fiber, it processes reflected light from a portion of the core included within the tubular structure that does not include Bragg gratings to produce a measurement of a force present at the distal region of the instrument.
    Type: Application
    Filed: July 9, 2019
    Publication date: October 31, 2019
    Inventors: Dawn K. Gifford, Federico Barbagli, Samuel Chang, Anoop B. Kowshik, Oliver Wagner, Michael Paris, Mark E. Froggatt
  • Patent number: 10443454
    Abstract: A valve drive device for an internal combustion engine is disclosed. The valve drive device has an axially displaceable cam element and an adjusting device with a first engagement element which displaces the cam element axially into a first switching position and a second engagement element which displaces the cam element axially into a second switching position. The adjusting device has a first slotted guide track in which the first engagement element is guided in the first switching position and a second slotted guide track in which the second engagement element is guided in the second switching position. The first engagement element is positively coupled to the second engagement element. The adjusting device includes a triggering device which holds the first engagement element fixedly in the second switching position counter to a restoring force. A method for axial displacement of a rotating cam element is also disclosed.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: October 15, 2019
    Assignee: Daimler AG
    Inventors: Juergen Bauer, Matthias Lahr, Marc Oliver Wagner, Benjamin Zeller
  • Publication number: 20190038365
    Abstract: A method performed by a computing system comprises receiving, from a fluoroscopic imager, having a first set of parameters, first fluoroscopic image data of a first fiducial marker within a surgical coordinate space. The method comprises receiving a configuration of the first fiducial marker within the surgical coordinate space. The method comprises determining a second set of parameters of the fluoroscopic imager in the surgical coordinate space based on the first flouroscopic image data and the configuration of the first fiducial marker. In some embodiments, determining the second set of parameters comprises developing a calibrated model of the fiducial marker in the surgical coordinate space from the first fluoroscopic image data and the configuration of the first fiducial marker.
    Type: Application
    Filed: February 10, 2017
    Publication date: February 7, 2019
    Applicant: INTUITIVE SURGICAL OPERATIONS, INC
    Inventors: Timothy D. Soper, Federico Barbagli, Caitlin Q. Donhowe, Vicent Duindam, Michael D. Paris, Oliver Wagner, Tao Zhao